TOP-5 dietary supplements for testosterone: comparison and analysis

TOP-5 dietary supplements for testosterone: comparison and analysis

I. D-asparaginic acid (D-ASPARTIC Acid-DAA)

1.1. The mechanism of action:

D-asparaginic acid (DAA) is an amino acid that is mainly found in neuroendocrine tissues involved in the production of hormones. Its proposed mechanism of action is associated with several key stages of hormonal synthesis and regulation.

• Stimulation of the hypothalamus and pituitary gland: DAA is considered a stimulant of the hypothalamic-pituitary system (GGS). The hypothalamus plays a central role in hormonal regulation, secreting a hormone releasing gonadotropins (GNRG). Grg, in turn, affects the pituitary gland, stimulating the release of luteinizing hormone (LH) and follicle -stimulating hormone (FSH).
• Increase in LH production: LH is a key hormone affecting the production of testosterone in Leydig’s cells located in the testicles in men. DAA presumably increases the secretion of LH with a pituitary gland, thereby increasing the stimulation of Leydig’s cells.
• Stimulation of testosterone production in Leydig’s cells: DAA can directly affect Lydig’s cells, enhancing the process of testosterone synthesis. This mechanism may be associated with the activation of enzymes involved in steroidogenesis, or with an increase in the sensitivity of Leydig’s cells to LH.
• The role of NMDA receptors: DAA is also an agonist of NMDA receptors (N-methyl-D-aspartat), which play an important role in neurotransmissia and regulation of hormonal secretion. Activation of NMDA receptors can contribute to the release of GNRG and LH, thereby increasing testosterone production.

1.2. Scientific research:

The effectiveness of the DAA in increasing the level of testosterone was investigated in several scientific works, the results of which were ambiguous.

• Positive results: Some studies have shown that DAA can significantly increase testosterone levels in men with a low level of this hormone. For example, in one study, the participants took 3 grams of DAA per day for 12 days. The results showed an increase in testosterone level by an average of 42%. Also, improvements were recorded in spermatogenesis.
• Ambiguous results: Other studies have not confirmed such a pronounced effect. In some works it was shown that the DAA can increase the level of testosterone only in the short term, and then the effect is reduced. It was also found that DAA can be more effective in men with an initially low level of testosterone.
• Lack of effect: In a number of studies, DAA did not demonstrate a significant impact on testosterone levels or muscle strength among trained men with a normal hormone level. This may indicate that the DAA can be ineffective for people with the optimal level of testosterone.
• Meta-analysis: The meta-analyzes that combine the results of several studies also provided ambiguous conclusions. Some meta-analyzes showed a moderate increase in testosterone levels when taking DAA, while others did not reveal a statistically significant effect.

1.3. Dosage and method of application:

• Recommended dosage: The most commonly recommended DAA dosage is 2-3 grams per day. The dosage can be divided into several techniques during the day.
• Method of application: DAA is usually taken orally, washed down with water. It can be consumed both on an empty stomach and during food.
• Duration of the course: The DAA method is usually from 2 to 12 weeks. After completing the course, it is recommended to take a break to prevent the body with the addiction and reduce the risk of side effects.
• Cycling: Some experts recommend cycling DAA, alternating periods of admission and breaks. For example, you can take DAA for 4 weeks, and then take a break for 2-4 weeks.
• Combining with other additives: DAA is often combined with other additives such as zinc, magnesium and vitamin D, to enhance the effect.

1.4. Possible side effects:

DAA is usually considered a safe addition subject to the recommended dosages. However, in some cases, side effects may occur.

• Gastrointestinal disorders: Some people may experience disorders of the gastrointestinal tract, such as nausea, diarrhea or abdominal pain.
• Headaches: In rare cases, DAA can cause headaches.
• Irritability: In some people, DAA can cause irritability or increased anxiety.
• Acne: In rare cases, the appearance of acne can be observed.
• Interaction with drugs: DAA can interact with some drugs, so before the reception it is recommended to consult a doctor, especially if you take any drugs.

1.5. Contraindications:

• Pregnancy and lactation: DAA is not recommended for pregnant and nursing women, since its influence on the development of the fetus and baby has not been studied.
• Individual intolerance: People with individual intolerance to DAA or other components of the additive should avoid its use.
• Kidney and liver diseases: People with kidney and liver diseases should consult a doctor before taking DAA.

II. Tribulus Tribulus Terrestris)

2.1. The mechanism of action:

Tribulus Terrestris is a plant traditionally used in Ayurvedic and Chinese medicine. It is believed that its impact on testosterone levels is associated with saponins contained in it, in particular, protorescine.

• Stimulation of LH production (debatable): Initially, it was believed that Tribulus Terrestris stimulates the production of luteinizing hormone (LH), which, in turn, stimulates Leydig’s cells in testos for the production of testosterone. However, later studies in public have not confirmed this theory.
• Impact on androgenic receptors (possibly): Some studies suggest that the active components of Tribulus Terrestris can have a direct effect on androgenic receptors, enhancing sensitivity to testosterone. This can lead to an improvement in sports indicators and libido, even without a significant increase in testosterone levels.
• Antioxidant properties: Tribulus Terrestris has antioxidant properties that can protect Leydig’s cells from damage caused by oxidative stress. Oxidizing stress can negatively affect the production of testosterone.
• Influence on libido: The most studied and confirmed effect of Tribulus Terrestris is its positive effect on libido and sexual function. The mechanism of this effect may be associated with an increase in the level of nitrogen oxide (NO), which improves blood flow in the genitals.

2.2. Scientific research:

Scientific data on the effectiveness of Tribulus Terrestris in increasing the level of testosterone in healthy men remain contradictory.

• Lack of significant influence on testosterone: Most studies did not show a significant increase in testosterone levels in healthy men taking Tribulus Terrestris. In some works, a slight increase in the level of testosterone was noted, but it was not statistically significant.
• A positive effect on libido and sexual function: Many studies have confirmed the positive effect of Tribulus Terrestris on libido and sexual function in men and women. Improving sexual function may be associated with an increase in nitrogen oxide (NO) and improving blood flow in the genitals.
• Improving sports indicators (dispute): Some studies have shown that Tribulus Terrestris can improve sports indicators such as strength and endurance, but these results are not stable and require further study.
• Animal research: Animal studies have shown that Tribulus Terrestris can increase testosterone levels, but the results of these studies are not always applicable to people.
• Quality of additives: It is important to note that the quality of Tribulus Terrestris additives can vary greatly. Some additives may contain a low concentration of active substances or be contaminated.

2.3. Dosage and method of application:

• Recommended dosage: The recommended Tribulus Terrestris dosage varies depending on the concentration of saponins in the extract. Usually the dosage is from 250 to 750 mg per day.
• Saponinov concentration: It is important to choose Tribulus Terrestris additives with a high concentration of saponins (at least 40%). The higher the concentration of saponins, the more effective the addition can be.
• Method of application: Tribulus Terrestris is usually taken orally, washed down with water. It can be consumed both on an empty stomach and during eating.
• Duration of the course: Tribulus Terrestris is usually from 4 to 12 weeks. After completing the course, it is recommended to take a break.
• Cycling: Some experts recommend cycling Tribulus Terrestris, alternating periods of admission and breaks.

2.4. Possible side effects:

Tribulus Terrestris is usually considered a safe addition subject to the recommended dosages. However, in some cases, side effects may occur.

• Gastrointestinal disorders: Some people may experience disorders of the gastrointestinal tract, such as nausea, diarrhea or abdominal pain.
• Insomnia: In rare cases, Tribulus Terrestris can cause insomnia.
• Irritability: In some people, Tribulus Terrestris can cause irritability or increased anxiety.
• Increased prostate (debatable): In some studies on animals, it was shown that Tribulus Terrestris can increase the size of the prostate. However, studies in public have not confirmed this effect.
• Interaction with drugs: Tribulus Terrestris can interact with some drugs, so before the intake it is recommended to consult a doctor, especially if you take any drugs.

2.5. Contraindications:

• Pregnancy and lactation: Tribulus Terrestris is not recommended for pregnant and lactating women, since its influence on the development of the fetus and baby has not been studied.
• Individual intolerance: People with individual intolerance to Tribulus Terrestris or other components of the additive should avoid taking it.
• Prostate diseases: People with prostate diseases should consult a doctor before taking Tribulus Terrestris.

III. Fenugreek

3.1. The mechanism of action:

Penalty (Trigonella Foenum-Graecum) is a plant whose seeds are traditionally used in cooking and medicine. It is believed that its influence on testosterone levels is associated with saponins contained in it, in particular, in fourostanol saponins.

• Aromatase inhibiting: The fencing can inhibit the enzyme aromatase, which turns testosterone into estrogen. Inhibition of aromatase can lead to an increase in testosterone levels and a decrease in estrogen levels.
• Improving the level of free testosterone: The fencing can increase the level of free testosterone, which is a biologically active form of testosterone. This can happen by reducing the level of globulin connecting sex hormones (GSPG). GSPG binds testosterone, making it less accessible to tissues of the body.
• Strengthening the action of testosterone: The fencing can enhance the action of testosterone, increasing the sensitivity of androgen receptors.
• Antioxidant properties: The fencing has antioxidant properties that can protect the Lydig cells from damage caused by oxidative stress.
• Impact of insulin: The fencing can improve insulin sensitivity, which can have a positive effect on testosterone levels. Insulin resistance can lead to a decrease in testosterone levels.

3.2. Scientific research:

Scientific data on the effectiveness of the fencing in increasing the level of testosterone in men are quite convincing.

• Improving the level of general testosterone: Many studies have shown that the fencing can increase the level of general testosterone in men.
• Improving the level of free testosterone: Studies also have shown that the fencing can increase the level of free testosterone.
• Improving libido and sexual function: The fencing showed a positive effect on libido and sexual function in men.
• Increase in muscle mass and strength: Some studies have shown that the fencing can help increase muscle mass and strength in combination with strength training.
• Improving the composition of the body: The fencing can help improve the composition of the body, a decrease in the percentage of fat and increase muscle mass.
• Safety: The fencing is usually considered a safe addition subject to the recommended dosages.

3.3. Dosage and method of application:

• Recommended dosage: The recommended dosage of the fencing is from 500 to 600 mg of extract per day.
• Saponinov concentration: It is important to choose the additives of a fencing with a high concentration of saponins (at least 50%).
• Method of application: The fences are usually taken orally, washed down with water. It can be consumed both on an empty stomach and during eating.
• Duration of the course: The course of reception of fences is usually from 8 to 12 weeks.
• Combination with nutrition: To achieve the best results, the fencing is recommended to combine with a balanced diet and regular physical exercises.

3.4. Possible side effects:

The fencing is usually considered a safe addition subject to the recommended dosages. However, in some cases, side effects may occur.

• Gastrointestinal disorders: Some people may experience disorders of the gastrointestinal tract, such as nausea, diarrhea or abdominal pain.
• Specific smell of the body: The fencing can give the body a specific smell, similar to the smell of maple syrup.
• Allergic reactions: In rare cases, allergic reactions to the fencil may occur.
• Reducing blood sugar: The fencing can reduce blood sugar, so people with diabetes should be careful when taking it.
• Interaction with drugs: The fencing can interact with some drugs, so before the reception it is recommended to consult a doctor, especially if you take any drugs.

3.5. Contraindications:

• Pregnancy: The car is not recommended for pregnant women, as it can stimulate uterine contractions.
• Individual intolerance: People with individual intolerance to the fencing or other components of the additive should avoid its use.
• Thyroid diseases: People with thyroid diseases should consult a doctor before taking a fenced party.

Iv. Zinc (Zinc)

4.1. The mechanism of action:

Zinc is an important trace element necessary for many biological processes in the body, including testosterone production.

• The role in the development of LH: Zinc is involved in the regulation of the production of luteinizing hormone (LH) with a pituitary gland. LG, as we already know, stimulates Lydig’s cells in testicles for the production of testosterone. Zinc deficiency can violate LH production and, therefore, reduce testosterone levels.
• Impact on aromatase: Zinc can inhibit an aromatase enzyme that turns testosterone into estrogen. Maintaining the optimal level of zinc can help reduce estrogen levels and increase testosterone levels.
• Maintaining the integrity of Leydig’s cells: Zinc plays an important role in maintaining the integrity and functioning of Leydig’s cells. Zinc deficiency can lead to damage to Leydig cells and a decrease in testosterone production.
• Antioxidant properties: Zinc has antioxidant properties that can protect Leydig cells from damage caused by oxidative stress.
• Role in spermatogenesis: Zinc plays an important role in spermatogenesis, the process of formation of sperm. Zinc deficiency can lead to a decrease in the quantity and quality of sperm.

4.2. Scientific research:

Scientific data confirm the important role of zinc in maintaining the normal level of testosterone.

• Zinc deficiency and low level of testosterone: Studies have shown that zinc deficiency is often associated with a low level of testosterone in men.
• Restoration of testosterone levels for deficiency: Zinc supplements can help restore the normal level of testosterone in men with a deficiency of this trace element.
• Impact of spermatogenes: Studies have confirmed the positive effect of zinc on spermatogenesis, an improvement in the quantity and quality of sperm.
• Influence on sports indicators (indirectly): Zinc can have an indirect impact on sports indicators by maintaining the normal level of testosterone and improving recovery after training.
• Additional research: Additional studies are needed to determine the optimal dosage of zinc to maintain the normal level of testosterone in various population groups.

4.3. Dosage and method of application:

• Recommended dosage: The recommended daily dose of zinc is 11 mg for men. However, with zinc deficiency or to achieve certain goals, the dosage can be increased to 25-40 mg per day.
• Forms of zinc: There are various forms of zinc, such as zinc gluconate, zinc picoline, zinc citrate and zinc oxide. Qing Picoline and Zinc Citrate are considered the most bioavailable forms.
• Method of application: Zinc is usually taken orally, washed down with water. It is recommended to take zinc while eating to improve its absorption.
• Duration of admission: The duration of zinc administration depends on the purpose of admission and individual needs.
• Combination with nutrition: It is important to take into account that some products, such as phitat contained in grain and legumes, can worsen the absorption of zinc.

4.4. Possible side effects:

Zinc is usually considered a safe addition subject to the recommended dosages. However, in some cases, side effects may occur.

• Gastrointestinal disorders: When taking high doses of zinc, disorders of the gastrointestinal tract, such as nausea, vomiting, diarrhea and abdominal pain, can occur.
• Copper deficiency: Long -term intake of high doses of zinc can lead to a shortage of copper. Copper is an important trace element necessary for many biological processes.
• Reduced immunity: In rare cases, taking high doses of zinc can reduce immunity.
• Metal taste in the mouth: Some people may experience a metal taste in the mouth when taking zinc.
• Interaction with drugs: Zinc can interact with some drugs, so before the start of taking, it is recommended to consult a doctor, especially if you take any drugs.

4.5. Contraindications:

• Individual intolerance: People with individual intolerance to zinc or other components of the additive should avoid its use.
• Kidney diseases: People with kidney diseases should consult a doctor before taking zinc.
• Crime metabolism: People with a violation of copper metabolism should be careful when taking zinc.

V. Vitamin D (Vitamin D)

5.1. The mechanism of action:

Vitamin D is a fat -soluble vitamin that plays an important role in the regulation of many biological processes in the body, including testosterone production. In fact, vitamin D acts as a run.

• Influence of Ladyiga cells: Vitamin D has a direct effect on Leydig’s cells in the testicles, stimulating the production of testosterone. Leydig cells have receptors to vitamin D, which allows it to directly affect their function.
• Influence on hypothalamus and pituitary gland: Vitamin D can affect the hypothalamic-pituitary system (GGS), adjusting the production of luteinizing hormone (LH).
• Reducing the level of GSPG: Vitamin D can reduce the level of globulin connecting sex hormones (GSPG). Reducing the level of GSPG leads to an increase in the level of free testosterone.
• Antioxidant properties: Vitamin D has antioxidant properties that can protect the lidig cells from damage caused by oxidative stress.
• Impact of insulin: Vitamin D can improve insulin sensitivity, which can have a positive effect on testosterone levels.

5.2. Scientific research:

Scientific data confirm the important role of vitamin D in maintaining the normal level of testosterone.

• Vitamin D deficiency and low testosterone level: Studies have shown that vitamin D deficiency is often associated with a low level of testosterone in men.
• Restoration of testosterone levels for deficiency: Vitamin D additives can help restore the normal level of testosterone in men with a deficiency of this vitamin.
• Influence on muscle mass and strength: Some studies have shown that vitamin D can help increase muscle mass and strength.
• Influence on sports indicators: Vitamin D can have a positive effect on sports indicators, such as endurance and strength.
• Additional research: Additional studies are needed to determine the optimal dosage of vitamin D to maintain the normal level of testosterone in various population groups.

5.3. Dosage and method of application:

• Recommended dosage: The recommended daily dose of vitamin D varies depending on the age, state of health and level of vitamin D in the blood. The usually recommended dose is from 600 to 2000 IU (international units) per day.
• Determination of vitamin D level: Before taking vitamin D additives, it is recommended to determine the level of vitamin D in the blood using analysis.
• Vitamin D forms: There are two main forms of vitamin D: vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). Vitamin D3 is considered more effective than vitamin D2.
• Method of application: Vitamin D is usually taken orally, washed down with water. It is recommended to take vitamin D during food containing fats to improve its absorption.
• Duration of admission: The duration of the intake of vitamin D depends on the purpose of admission and individual needs.
• Combining with other vitamins and minerals: Vitamin D is recommended to be taken in combination with vitamin K2 to improve its absorption and prevent vascular calcification.

5.4. Possible side effects:

Vitamin D is usually considered a safe addition subject to the recommended dosages. However, in some cases, side effects may occur.

• Hypercalcemia: When taking high doses of vitamin D, hypercalcemia (an increased level of calcium in the blood) can occur.
• Nausea, vomiting, constipation: With hypercalcemia, nausea, vomiting and constipation may occur.
• Weakness, fatigue: With hypercalcemia, weakness and fatigue can occur.
• Renal failure: In rare cases, taking high doses of vitamin D can lead to renal failure.
• Interaction with drugs: Vitamin D can interact with some drugs, so before the reception it is recommended to consult a doctor, especially if you take any drugs.

5.5. Contraindications:

• Hypercalcemia: People with hypercalcemia should avoid taking vitamin D.
• Individual intolerance: People with individual intolerance to vitamin D or other components of the additive should avoid its use.
• Kidney diseases: People with kidney diseases should consult a doctor before taking vitamin D.
• Sarcoidosis: People with sarcoidosis should be careful when taking vitamin D.

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