Natural dietary supplements for joint treatment: Full review
Section 1: Understanding the pain in the joints and the role of dietary supplements
Joint pain is a common phenomenon affecting millions of people around the world. They can vary from mild discomfort to exhausting pain, significantly reducing the quality of life. The causes of joint pain are diverse and include:
- Osteoarthritis (OA): Degenerative joint disease, characterized by gradual destruction of cartilage.
- Rheumatoid arthritis (RA): Autoimmune disease causing inflammation of the joints and other tissues.
- Gout: The type of arthritis caused by the accumulation of uric acid crystals in the joints.
- Injuries: Stretches, dislocations, fractures and other injuries can lead to joint pain.
- Bursit: Inflammation of the brush, a small bag filled with liquid, which softens the movement between bones, tendons and muscles.
- Tendinitis: Inflammation of the tendons connecting the muscles to the bones.
- Volchanka: Autoimmune disease that can affect joints, skin, kidneys and other organs.
- Fibromyalgia: A chronic disease characterized by common pain in muscles and joints, fatigue and sleep problems.
Traditional methods of treating joint pain often include painkillers, non -steroidal anti -inflammatory drugs (NSAIDs), corticosteroids and physiotherapy. However, these methods can have side effects, and some people are looking for alternative or additional approaches, such as the use of biologically active additives (BADs).
Bades are products designed to supplement the diet and contain vitamins, minerals, herbs or other substances. Some dietary supplements are positioned as means to relieve joint pain, reduce inflammation and improve joint function. It is important to understand that dietary supplements are not medicines and are not intended for the treatment or cure of any diseases. However, some studies show that certain dietary supplements can have a positive effect on the health of the joints.
Section 2: Glucosamine and Chondroitin: Classic components
Glucosamine and chondroitin are the two most common and studied dieters for treating joint pain, especially with osteoarthritis.
- Glucosamine: The natural substance that is produced in the body and is a building block for cartilage. It is assumed that glucosamine helps restore damaged cartilage and reduce pain and inflammation. There are various forms of glucosamine, including glucosamine sulfate, hydrochloride glucosamine and n-acetylhlucosamine. Glucosamine sulfate is the most studied form.
- Chondroitin: Another natural substance that is part of the cartilage. Chondroitin helps to retain water in cartilage, which contributes to its elasticity and resistance to loads. It is assumed that chondroitin also has anti -inflammatory properties.
The mechanism of action:
Glucosamine and chondroitin work synergically, complementing each other’s effect. Glucosamine provides the body with building blocks to restore cartilage, and chondroitin helps to protect cartilage from further destruction. In addition, both substances have anti -inflammatory properties that can help reduce pain and edema in the joints.
Research:
The research results of glucosamine and chondroitin are contradictory. Some studies show that they can help reduce pain and improve joint function in people with osteoarthritis, while other studies do not detect a significant effect. Differences in the results can be associated with differences in the design of research, dosages of the drugs used, type of glucosamine and chondroitin, as well as in patient characteristics.
Side effects:
Glucosamine and chondroitin are usually considered safe, but can cause some side effects, such as nausea, diarrhea, constipation and heartburn. People with allergies for seafood should be cautioned when taking glucosamine, as it is often obtained from mollusks. It is also necessary to take into account the interaction with anticoagulants (drugs that thin the blood).
Dosage:
The recommended dosage of glucosamine is usually 1,500 mg per day, divided into several tricks. The recommended dosage of chondroitin is usually 1200 mg per day, divided into several tricks. It is important to follow the instructions on the packaging of the product and consult a doctor before the reception.
Section 3: Methyl sulfonylmetatan (MSM): Sera for the joints
Methyl sulfonylmetatan (MSM) is an organic compound of sulfur, which is naturally found in plants, animals and humans. Sure is an important component of connective tissue, including cartilage, ligaments and tendons. MSM is often used as a dietary supplement to relieve joint pain, reduce inflammation and improve mobility.
The mechanism of action:
MSM has several mechanisms of action that can be useful for joint health:
- Anti -inflammatory action: MSM can help reduce inflammation, inhibiting the release of inflammatory mediators.
- Antioxidant action: MSM has antioxidant properties that can help protect the cells from damage to free radicals.
- Improving collagen synthesis: MSM can contribute to the synthesis of collagen, an important protein, which forms the basis of cartilage, ligaments and tendons.
- Reducing pain sensitivity: MSM can help reduce pain sensitivity by blocking the transmission of pain signals.
Research:
Some studies show that MSM can help reduce pain and improve joint function in people with osteoarthritis. For example, one study showed that the intake of MSM for 12 weeks significantly reduced the pain and improved the joint function in people with osteoarthritis of the knee joint.
Side effects:
MSM is usually considered safe, but can cause some side effects, such as nausea, diarrhea, bloating and headache.
Dosage:
The recommended MSM dosage is usually 1-3 grams per day, divided into several tricks. It is important to follow the instructions on the packaging of the product and consult a doctor before the reception.
Section 4: Kurkumin: powerful anti -inflammatory agent
Kurkumin is an active compound contained in turmeric, spices widely used in Indian cuisine. Kurkumin is known for its powerful anti -inflammatory and antioxidant properties. It is widely used as a dietary supplement to relieve joint pain, reduce inflammation and improve the general state of health.
The mechanism of action:
Kurkumin has many mechanisms of action that can be useful for joint health:
- Inhibition of inflammatory pathways: Kurkumin inhibits various inflammatory pathways, including NF-κB, COX-2 and 5-Lox.
- Antioxidant action: Kurkumin has antioxidant properties that can help protect cells from damage to free radicals.
- Reducing the activity of enzymes destroying cartilage: Kurkumin can help reduce the activity of enzymes that destroy cartilage, such as matrix metal proproteinase (MMP).
- Improving collagen synthesis: Kurkumin can contribute to the synthesis of collagen, an important protein, which forms the basis of cartilage, ligaments and tendons.
Research:
Numerous studies have shown that Kurkumin can help reduce pain and improve joint function in people with osteoarthritis and rheumatoid arthritis. For example, one study showed that Kurkumin is as effective as Ibuprofen, in relief of pain in people with osteoarthritis of the knee joint.
Bioavailability:
One of the problems with turmeric is its low bioavailability, that is, it is poorly absorbed by the body. To improve the bioavailability of curcumin, it is often combined with piperin, a compound contained in black pepper. Piperin increases the absorption of curcumin in the intestines. There are also various forms of curcumin with improved bioavailability, such as liposomal curcumin and turmeric with phytosomes.
Side effects:
Kurkumin is usually considered safe, but can cause some side effects, such as nausea, diarrhea and stomach disorder.
Dosage:
The recommended dosage of curcumin varies depending on the form of curcumin and individual needs. It is important to follow the instructions on the packaging of the product and consult a doctor before the reception.
Section 5: Omega-3 fatty acids: the key to the anti-inflammatory effect
Omega-3 fatty acids is a type of polyunsaturated fatty acids that are important to human health. The most important omega-3 fatty acids are eicopascentaenoic acid (EPK) and daily oxaenoic acid (DGK). Omega-3 fatty acids are found in fatty fish, such as salmon, tuna and sardines, as well as in plant sources, such as flaxseed, chia seeds and walnuts. Omega-3 fatty acids have anti-inflammatory properties and can be useful to relieve joint pain.
The mechanism of action:
Omega-3 fatty acids have an anti-inflammatory effect, inhibiting the production of inflammatory mediators, such as prostaglandins and leukotrienes. They can also contribute to the production of anti -inflammatory mediators, such as resolvines and protective.
Research:
Numerous studies have shown that omega-3 fatty acids can help reduce pain and improve joint function in people with rheumatoid arthritis and osteoarthritis. For example, one study showed that taking omega-3 fatty acids for 12 weeks significantly reduced the pain and improved joint function in people with rheumatoid arthritis.
Sources:
There are two main sources of omega-3 fatty acids:
- Fish oil: Fish oil is a rich source of EPK and DGK. It is available in the form of capsules and liquids.
- Plant sources: Plant sources, such as linen seeds, chia seeds and walnuts, contain alpha-linolenic acid (Alc), which can be transformed into EPK and DHC in the body. However, the transformation of the ALK into EPC and the DGK is not very effective.
Side effects:
Omega-3 fatty acids are usually considered safe, but can cause some side effects, such as fish belching, nausea and diarrhea.
Dosage:
The recommended dosage of omega-3 fatty acids varies depending on individual needs. It is important to follow the instructions on the packaging of the product and consult a doctor before the reception.
Section 6: S-adenosylmetionine (SAME): Alternative for cartilage
S-adenosylmetionine is a natural compound that is produced in the body and is involved in many biochemical reactions. Same plays an important role in the synthesis of cartilage, neurotransmitters and DNA. It is used as a dietary supplement to relieve joint pain, improve mood and maintain liver function.
The mechanism of action:
Same has several mechanisms of action that can be useful for joint health:
- Synthesis of cartilage: Same can stimulate the synthesis of proteoglycans, important cartilage components.
- Anti -inflammatory action: Same has anti -inflammatory properties that can help reduce pain and edema in the joints.
- Anesthetic effect: Same can help reduce pain sensitivity.
Research:
Some studies have shown that SAME can help reduce pain and improve joint function in people with osteoarthritis. For example, one study showed that Same is as effective as NSAIDs in relief of pain in people with osteoarthritis of the knee joint.
Side effects:
Same can cause some side effects, such as nausea, diarrhea, constipation and headache. People with bipolar disorder should avoid taking SAME, as it can cause mania.
Dosage:
The recommended same dosage varies depending on individual needs. It is important to follow the instructions on the packaging of the product and consult a doctor before the reception.
Section 7: Boswellion: Ancient remedy for inflammation
Boswellion is an extract from the resin of wood Boswellia Serrata, which grows in India and in the Middle East. Boswellia is used in traditional Ayurvedic medicine to treat various diseases, including arthritis. Boswellia contains bosvelic acids that have anti -inflammatory properties.
The mechanism of action:
Bosvevel acids inhibit the 5-lipoxygenase enzyme (5-Lox), which is involved in the production of leukotrienes, inflammatory mediators. Inhibiting 5 -lox, Boswelliya can help reduce inflammation and joint pain.
Research:
Some studies have shown that Boswellion can help reduce pain and improve joint function in people with osteoarthritis and rheumatoid arthritis. For example, one study showed that taking Boswellial extract for 8 weeks significantly reduced the pain and improved joint function in people with an osteoarthritis of the knee joint.
Side effects:
Boswellia is usually considered safe, but can cause some side effects, such as nausea, diarrhea and stomach disorder.
Dosage:
The recommended bosvellia dosage varies depending on the concentration of bosvelic acids in the extract. It is important to follow the instructions on the packaging of the product and consult a doctor before the reception.
Section 8: Avocado and soye unhumbered compounds (ACU): A unique approach
Avocado and soy in neo -smashed compounds (ACU) are an extract obtained from avocados and soybeans. ACS contains various compounds that can be useful for joint health, including phytosterins, vitamin E and omega-3 fatty acids.
The mechanism of action:
ACS has several mechanisms of action that can be useful for joint health:
- Inhibition of inflammatory mediators: ACU can inhibit the production of inflammatory mediators, such as prostaglandins and leukotrienes.
- Synthesis of cartilage: ACU can stimulate the synthesis of collagen and proteoglycans, important cartilage components.
- Carriage protection from destruction: ACS can help protect the cartilage from destruction by inhibiting enzymes, such as matrix metal proproteinase (MMP).
Research:
Some studies have shown that ACS can help reduce pain and improve joint function in people with osteoarthritis. For example, one study showed that the aircraft reception for 3 months significantly reduced the pain and improved the joint function in people with osteoarthritis of the knee joint.
Side effects:
ACS is usually considered safe, but can cause some side effects, such as stomach disorder and allergic reactions.
Dosage:
The recommended ACS dosage is usually 300 mg per day. It is important to follow the instructions on the packaging of the product and consult a doctor before the reception.
Section 9: Collagen: Building material for the joints
Collagen is the main structural protein in the body, which forms the basis of the skin, bones, tendons, ligaments and cartilage. With age, the production of collagen in the body decreases, which can lead to a deterioration in the condition of the joints, wrinkles on the skin and other problems. Reception of additives with collagen can help maintain joint health and improve the skin condition.
Types of collagen:
There are several types of collagen, but the most common are:
- Type and: The most common type of collagen contained in the skin, bones, tendons and ligaments.
- Type II: The main type of collagen contained in the cartilage.
- Type III: Contained in the skin, muscles and blood vessels.
The mechanism of action:
Reception of collagen in the form of additives can help stimulate the production of its own collagen in the body. Collagen can also help reduce inflammation and joint pain.
Research:
Some studies have shown that collagen intake can help reduce pain and improve joint function in people with osteoarthritis. For example, one study showed that taking type II collagen for 6 months significantly reduced the pain and improved joint function in people with an osteoarthritis of the knee joint.
Side effects:
Collagen is usually considered safe, but can cause some side effects, such as stomach disorder and allergic reactions.
Dosage:
The recommended collagen dosage varies depending on the type of collagen and individual needs. It is important to follow the instructions on the packaging of the product and consult a doctor before the reception.
Section 10: Other potential dietary supplements and plant remedies
In addition to the above, there are other dietary supplements and plant agents that can be useful for treating joint pain:
- Hyaluronic acid: Natural substance contained in joint fluid and cartilage. Hyaluronic acid helps to lubricate the joints and soften blows.
- Green tea extract: Contains antioxidants that can help reduce inflammation.
- Ginger: It has anti -inflammatory properties and can help reduce joint pain.
- Claw Devil: A plant used in traditional African medicine to treat joint pain.
- Nettle: It has anti -inflammatory properties and can help reduce joint pain.
Section 11: Important considerations and warnings
Before taking any dietary supplements for treating joint pain, it is important to consider the following points:
- Consult a doctor: Before taking any dietary supplements, especially if you have any diseases or take any medication, be sure to consult your doctor.
- Choose quality products: Buy dietary supplements from reliable manufacturers who test their products for cleanliness and efficiency.
- Observe the dosage: Do not exceed the recommended dosage of dietary supplements.
- Be patient: Bades do not work instantly. It may take several weeks or months to see the results.
- Follow side effects: If you experience any side effects, stop taking a dietary supplement and consult a doctor.
- Bades are not a replacement for traditional treatment: Bades can be useful to relieve joint pain, but they should not replace the traditional treatment prescribed by a doctor.
Section 12: Integrative approach to joint treatment
The most effective approach to treating joint pain often includes a combination of various methods, including:
- Medication: Anesthetizing, NSAIDs, corticosteroids.
- Physiotherapy: Exercises to strengthen muscles and improve joint mobility.
- Bad: Glucosamine, chondroitin, MSM, curcumin, omega-3 fatty acids and others.
- Life change change: Weight loss, regular exercises, healthy nutrition.
- Alternative treatment methods: Acupuncture, massage, yoga.
An integrative approach allows you to adapt treatment to the individual needs of the patient and achieve the best results.
Section 13: Future research areas
Studies in the field of dietary supplements for the treatment of joints continue. In the future, we can see new and more effective dietary supplements, as well as a better understanding of the mechanisms of action of existing dietary supplements. Important areas of research include:
- Identification of new targets for dietary supplements: The study of new molecular targets that can be used to develop new dietary supplements to treat joint pain.
- Development of dietary supplements with improved bioavailability: The development of new forms of dietary supplements with improved bioavailability so that they can be more effectively learned by the body.
- Conducting large -scale clinical research: Conducting large -scale clinical research to assess the effectiveness and safety of dietary supplements for treating joint pain.
- Studying interactions between dietary supplements and medicines: The study of possible interactions between dietary supplements and medicines in order to avoid undesirable side effects.
Continuation of research will allow us to better understand the role of dietary supplements in treating joint pain and develop more effective and safe treatment strategies.