Bades to protect the brain from aging: Detailed leadership
Section 1: Understanding the aging of the brain and its consequences
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1 Age -related changes in the brain:
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- 1 Neural losses: The aging is inevitably connected with the gradual loss of neurons, especially in areas that are critical for training and memory, such as hippocampus and prefrontal bark. These losses contribute to a decrease in cognitive functions.
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- 2 Reduced neuroplasticity: Neuroplasticity, the ability of the brain to adapt and form new connections, decreases with age. This makes it difficult to teach new skills and adaptation to changing circumstances.
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- 3 Violation of neurotransmission: The effectiveness of signal transmission between neurons is reduced due to changes in the levels and functions of neurotransmitters, such as acetylcholine, dopamine and serotonin. This can lead to problems with memory, attention and mood.
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- 4 Access of protein units: With age, abnormal protein units accumulate in the brain, such as beta-amyloid and tau-white, which are associated with the development of neurodegenerative diseases, such as Alzheimer’s disease.
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- 5 Reduced blood supply to the brain: With age, blood vessels that feed the brain can become less flexible and more susceptible to the formation of plaques, which leads to a decrease in blood supply and oxygen support for the brain.
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- 6 Increase in inflammation: Chronic inflammation in the brain caused by various factors, including oxidative stress and immune reactions, plays an important role in brain aging and the development of neurodegenerative diseases.
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- 7 Microglia changes: Microglia, the immune cells of the brain, become less effective in removing garbage and more prone to the release of pro -inflammatory substances, which contributes to non -sleeping.
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2 Factors affecting brain aging:
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- 1 Genetic predisposition: Genetics plays a significant role in determining the speed and degree of aging of the brain. Some genes can increase the risk of developing neurodegenerative diseases, while others can have a protective effect.
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- 2 Life: An unhealthy lifestyle, including poor nutrition, lack of physical activity, smoking and alcohol abuse, can accelerate brain aging.
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- 3 Diet: A high content of saturated fats, sugar and treated foods can contribute to inflammation and oxidative stress, negatively affecting the health of the brain.
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- 4 Physical activity: The absence of regular physical exercises is associated with the deterioration of cognitive functions and an increased risk of developing neurodegenerative diseases.
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- 5 Smoking: Smoking damages blood vessels and reduces blood supply to the brain, increasing the risk of dementia.
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- 6 Alcohol abuse: Excessive alcohol consumption can damage neurons and worsen cognitive functions.
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- 7 Stress: Chronic stress can lead to the release of cortisol, stress hormone that can damage neurons and worsen memory.
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- 8 Dream: The lack of sleep can violate the processes of memory consolidation and increase the risk of developing neurodegenerative diseases.
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- 9 Environment: The influence of pollutants and toxins in the environment can damage the brain and accelerate aging.
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- 10 Social isolation: Social isolation and lack of communication can negatively affect cognitive functions and increase the risk of dementia.
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3 The consequences of aging of the brain:
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- 1 Reducing cognitive functions: The aging of the brain leads to a decrease in cognitive functions, including memory, attention, speed of information processing and executive functions.
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- 2 Memory problems: For forgetfulness, difficulties with memorizing new information and recalling old events are common problems associated with brain aging.
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- 3 Reduced attention: Aging can complicate the concentration of attention and switching between tasks.
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- 4 Slow down the speed of information processing: With age, the brain can more slowly process information, which can lead to a slowdown in the reaction and difficulties in solving problems.
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- 5 Violation of executive functions: Executive functions, such as planning, making decisions and impulse control, can worsen with age.
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- 6 Increased risk of neurodegenerative diseases: Aging is the main risk factor for the development of neurodegenerative diseases, such as Alzheimer’s disease and Parkinson’s disease.
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- 7 Changes in mood: Aging can lead to changes in mood, such as depression, anxiety and irritability.
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- 8 Reducing social activity: Cognitive and physical changes associated with aging can lead to a decrease in social activity and isolation.
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- 9 Reducing the quality of life: All these consequences of the aging of the brain can negatively affect the quality of life and independence.
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Section 2: The role of dietary supplements in protecting the brain from aging
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1 Mechanisms for the action of dietary supplements to protect the brain:
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- 1 Antioxidant Protection: Many dietary supplements have antioxidant properties that help protect the brain from damage to free radicals formed in the process of oxidative stress.
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- 2 Anti -inflammatory action: Some dietary supplements have anti -inflammatory properties that help reduce inflammation in the brain associated with aging and neurodegenerative diseases.
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- 3 Improving blood supply to the brain: Some dietary supplements can improve the blood supply to the brain, providing it with a sufficient amount of oxygen and nutrients.
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- 4 Support for neurotransmissions: Some dietary supplements can support the function of neurotransmitters, such as acetylcholine, dopamine and serotonin, which play an important role in cognitive functions.
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- 5 Neurogenesis stimulation: Some dietary supplements can stimulate neurogenesis, the process of formation of new neurons in the brain.
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- 6 Protection against protein units: Some dietary supplements can help protect the brain from the accumulation of abnormal protein units, such as beta-amyloid and tau-white.
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- 7 Support for mitochondrial function: Some dietary supplements can support the function of mitochondria, cell energy stations that play an important role in brain health.
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2 The main dietary supplements to protect the brain from aging:
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- 1 Omega-3 fatty acids: Omega-3 fatty acids, especially DGK (non-achexaenoic acid), are important components of the cell membranes of the brain and play an important role in cognitive functions. They have anti -inflammatory properties and can protect the brain from damage.
- The mechanism of action: They are integrated into cell membranes, improve neurotransmission, have an anti -inflammatory effect, and reduce the risk of Alzheimer’s disease.
- Dosage: 1-2 grams of DHK per day is recommended.
- Sources: Fish oil, linseed oil, chia seeds, walnuts.
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- 2 Curcumin: Kurkumin, the active ingredient of turmeric, has powerful antioxidant and anti -inflammatory properties. It can protect the brain from damage by free radicals and reduce inflammation.
- The mechanism of action: Antioxidant, anti -inflammatory action, neurona protection, stimulation of neurogenesis.
- Dosage: 500-1000 mg per day, preferably in the form with improved bioavailability (for example, with piperin).
- Sources: Fears (Speece), bady with kady.
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- 3 Resveratrol: Resveratrol is a polyphenol contained in red wine, grapes and berries. It has antioxidant and anti -inflammatory properties and can protect the brain from damage.
- The mechanism of action: Antioxidant, activation of sirtuins (longevity genes), neurons protection, improvement of blood supply to the brain.
- Dosage: 150-500 mg per day.
- Sources: Red wine, grapes, berries, dietary supplements with resveratrol.
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- 4 Coenzim Q10 (COQ10): COQ10 is an antioxidant that plays an important role in the production of energy in cells. It can protect the brain from oxidative stress and maintain the function of mitochondria.
- The mechanism of action: Antioxidant, support for mitochondrial function, neuron protection.
- Dosage: 100-300 mg per day.
- Sources: Meat, fish, dietary supplements with COQ10.
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- 5 Ginkgo Biloba: Ginko biloba is a plant extract that improves blood supply to the brain and has antioxidant properties. It can improve memory and cognitive functions.
- The mechanism of action: Improving blood supply to the brain, antioxidant, protection of neurons.
- Dosage: 120-240 mg per day.
- Sources: Bades with Ginko Biloba.
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- 6 Phosphateidix (PS): Phosphatidylserin is a phospholipid, which is an important component of cell membranes of the brain. It can improve memory and cognitive functions.
- The mechanism of action: Support for the structure and functions of cell membranes, improvement of neurotransmission, improvement of memory.
- Dosage: 100-300 mg per day.
- Sources: Soy, fish, dietary supplements with phosphatidylserin.
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- 7 Acetyl-L-carnitine: Acetyl-L-carnitine is an amino acid that helps to transport fatty acids to mitochondria for energy production. It can improve cognitive functions and protect the brain from damage.
- The mechanism of action: Improving energy metabolism in the brain, antioxidant, protection of neurons.
- Dosage: 500-1500 mg per day.
- Sources: Meat, dietary supplements with acetyl-L-carnitine.
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- 8 B vitamins B: Group B vitamins, especially B12, B6 and folic acid, play an important role in brain health. They are necessary for the normal function of the nervous system and can protect the brain from damage.
- The mechanism of action: Support for the function of the nervous system, participation in the synthesis of neurotransmitters, protection of neurons.
- Dosage: According to the doctor’s recommendations or the instructions on the pack of dietary supplements.
- Sources: Meat, fish, dairy products, eggs, vegetables, dietary supplements with vitamins of group B.
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- 9 Vitamin D: Vitamin D plays an important role in brain health and can protect against neurodegenerative diseases.
- The mechanism of action: Support for the function of the nervous system, regulation of the immune system, protection of neurons.
- Dosage: According to the doctor’s recommendations, usually 1000-4000 IU per day.
- Sources: Sunlight, oily fish, egg yolk, dietary supplements with vitamin D.
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- 10 Magnesium: Magnesium plays an important role in the health of the brain and can protect against neurodegenerative diseases.
- The mechanism of action: Regulation of neurotransmissions, protection of neurons, decrease in inflammation.
- Dosage: 200-400 mg per day.
- Sources: Green leaf vegetables, nuts, seeds, whole grain products, dietary supplements with magnesium.
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- 11 Alpha-lipoic acid (ALA): ALA is a powerful antioxidant that can penetrate both the aqueous and the fat environment of cells, providing protection against oxidative stress. She also plays a role in energy metabolism.
- The mechanism of action: Antioxidant, improvement of energy metabolism, protection of neurons.
- Dosage: 200-600 mg per day.
- Sources: Bades with alpha lipoic acid.
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- 12 N-Acetylcistein (NAC): NAC is the predecessor of glutathione, one of the most important antioxidants in the body. It helps to protect the brain from oxidative stress and inflammation.
- The mechanism of action: Antioxidant, glutathione support, neurons protection.
- Dosage: 600-1800 mg per day.
- Sources: Bugs with n-acetilcyne.
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3 How to choose suitable dietary supplements:
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- 1 Consultation with a doctor: Before taking any dietary supplements, it is necessary to consult a doctor in order to make sure their safety and the absence of contraindications.
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- 2 Individual needs: The choice of dietary supplements should be based on individual needs and health status.
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- 3 Quality and safety: It is important to choose dietary supplements from reliable manufacturers that guarantee the quality and safety of their products.
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- 4 Study of research: Before buying Bad, it is useful to familiarize yourself with scientific research confirming its effectiveness.
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- 5 Composition: Carefully study the composition of Bad to make sure that there are no undesirable ingredients.
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- 6 Dosage: Follow the recommended dosage indicated on the pack of dietary supplements.
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- 7 Output form: Choose a convenient dietary supplement release form (tablets, capsules, powder, etc.).
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- 8 Reviews: Check out the reviews of other consumers about a particular diet.
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- 9 Combination with other drugs: Tell the doctor about all your medicines and dietary supplements to avoid unwanted interactions.
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- 10 Gradual introduction: Start taking dietary supplements with small doses, gradually increasing them to the recommended to evaluate tolerance.
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Section 3: Additional strategies to protect the brain from aging
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1 Healthy lifestyle:
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- 1 Proper nutrition: A balanced diet rich in fruits, vegetables, whole grain products, low -fat protein and healthy fats is necessary for brain health.
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- 2 Regular physical exercises: Physical activity improves blood supply to the brain, stimulates neurogenesis and reduces the risk of developing neurodegenerative diseases.
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- 3 Sufficient sleep: The lack of sleep can disrupt cognitive functions and increase the risk of dementia. It is recommended to sleep 7-8 hours a day.
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- 4 Stress management: Chronic stress can damage neurons and worsen memory. It is important to learn how to effectively manage stress with the help of relaxation, meditation or yoga techniques.
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- 5 Refusal of smoking and abuse of alcohol: Smoking and alcohol abuse damage the brain and accelerate aging.
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2 Cognitive training:
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- 1 Regular mental exercises: The solution of crosswords, puzzles, reading, studying new languages and other mental exercises help maintain brain activity and improve cognitive functions.
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- 2 Training in new skills: Training in new skills stimulates neuroplasticity and helps the brain adapt to changing circumstances.
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- 3 Social activity: Communication with other people, participation in social events and maintaining social ties help maintain cognitive functions and reduce the risk of dementia.
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3 Medical examinations:
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- 1 Regular examinations at the doctor: Regular medical examinations help to identify and treat diseases that can affect brain health.
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- 2 Control of blood pressure and cholesterol level: High blood pressure and high cholesterol can damage the blood vessels of the brain and increase the risk of dementia.
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- 3 Screening on neurodegenerative diseases: In the presence of risk factors or suspicions of neurodegenerative diseases, screening must be passed.
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Section 4: Scientific research and evidence of dietary supplements
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1 Clinical research:
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- 1 Omega-3 fatty acids: Numerous clinical studies have shown that the use of omega-3 fatty acids can improve cognitive functions, especially in the elderly.
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- 2 Curcumin: Studies have shown that Kurkumin can improve memory and attention, as well as reduce the risk of developing Alzheimer’s disease.
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- 3 Resveratrol: Some studies have shown that resveratrol can improve the blood supply to the brain and cognitive functions.
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- 4 Ginkgo Biloba: Clinical studies have shown that Ginko Biloba can improve memory and cognitive functions in people with dementia.
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- 5 Phosphateidixine: Studies have shown that phosphatidylserin can improve memory and cognitive functions in the elderly.
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2 Meta analysis:
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- 1 Omega-3 fatty acids: The meta-analyzes of clinical studies confirmed that the use of omega-3 fatty acids can improve cognitive functions.
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- 2 Ginkgo Biloba: The meta-analyzes have shown that ginko biloba can be effective for improving cognitive functions in people with dementia.
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3 Observatory studies:
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- 1 Mediterranean diet: Observatory studies have shown that compliance with the Mediterranean diet rich in fruits, vegetables, whole grain products and healthy fats is associated with improving cognitive functions and a decrease in the risk of developing neurodegenerative diseases.
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Section 5: Cautions and possible side effects
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1 Possible side effects:
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- 1 Omega-3 fatty acids: Digestive disorders are possible, such as nausea, diarrhea and heartburn.
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- 2 Curcumin: In rare cases, digestive disorders are possible.
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- 3 Resveratrol: In rare cases, digestive disorders are possible.
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- 4 Ginkgo Biloba: Headaches, dizziness and digestive disorders are possible.
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- 5 Phosphateidixine: Disgrace of digestion and insomnia are possible.
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2 Interaction with drugs:
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- 1 Omega-3 fatty acids: They can strengthen the effect of anticoagulants.
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- 2 Ginkgo Biloba: It can interact with anticoagulants and anti -signs.
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3 Contraindications:
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- 1 Pregnancy and breastfeeding: The safety of many dietary supplements during pregnancy and breastfeeding has not been established.
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- 2 Liver and kidney diseases: Some dietary supplements can be contraindicated in liver and kidney diseases.
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- 3 Allergies: Some people can be allergic to certain dietary supplements.
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4 The importance of consulting a doctor:
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- 1 Individual features: Before taking any dietary supplements, it is necessary to consult a doctor in order to verify their safety and the absence of contraindications, taking into account your individual characteristics and health status.
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Section 6: new directions in studies of aging of the brain and dietary supplements
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1 New molecules and compounds:
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- 1 Spermidin: Spermine is a polyamine that is contained in many foods and plays an important role in autophagy, the process of cell treatment. Studies show that spermin can improve cognitive functions and protect against neurodegenerative diseases.
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- 2 Pyrrolokhinolinhinone (PQ): PQq is a cofactor that plays an important role in mitochondrial function. Studies show that PQQ can improve cognitive functions and protect from oxidative stress.
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- 3 Nicotinamide riboside (NR): NR is the predecessor of nicotinin adenin dinucleotide (NAD+), a coofer, which plays an important role in energy metabolism and cellular health. Studies show that NR can improve cognitive functions and protect against neurodegenerative diseases.
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2 Targeting of specific aging mechanisms:
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- 1 Senolitics: Senolics are substances that selectively destroy aging cells that contribute to inflammation and damage to tissues. Studies show that haymaking can improve brain health and slow down aging.
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- 2 Activation of autophagy: Autophagy is the process of cellular cleaning that removes damaged organelles and proteins. Activation of autophagy can help protect the brain from aging and neurodegenerative diseases.
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3 Personalized approach:
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- 1 Genetic testing: Genetic testing can help determine the individual risks of developing neurodegenerative diseases and choose the most suitable dietary supplements and strategies to protect the brain.
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- 2 Assessment of cognitive functions: Regular assessment of cognitive functions can help monitor progress and adjust the strategies of brain protection.
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Section 7: Summary of key recommendations
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1 Compliance with a healthy lifestyle:
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- 1 Proper nutrition, regular physical exercises, sufficient sleep, stress management and rejection of bad habits.
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2 Reception of dietary supplements for brain protection:
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- 1 Omega-3 fatty acids, kurkumin, resveratrol, coenzyme Q10, ginko biloba, phosphatidylserin, acetyl-L-carnitine, vitamins of group B, vitamin D, magnesium, alpha-lipoic acid, n-acetylcystein.
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3 Regular cognitive training:
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- 1 Mental exercises, teaching new skills, social activity.
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4 Medical examinations and consultations with a doctor:
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- 1 Regular examinations at the doctor, control of blood pressure and cholesterol, screening at neurodegenerative diseases, consultation with a doctor before taking any dietary supplements.
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