Dietary supplements with plant extracts to relieve joint pain

Bades with plant extracts to relieve joint pain: exhaustive review

I. Understanding joint pain and the role of dietary supplements

The pain in the joints, or arthralgia, is a common phenomenon affecting millions of people around the world. It can be caused by various factors, including osteoarthritis, rheumatoid arthritis, injuries, infections and autoimmune diseases. Symptoms vary from slight discomfort to exhausting pain, limiting mobility and reducing the quality of life.

Traditional methods of treating joint pain often include non -steroidal anti -inflammatory drugs (NSAIDs), analgesics and in some cases corticosteroids. However, these drugs can cause side effects, especially with prolonged use. In this regard, many people turn to alternative approaches, such as biologically active additives (dietary supplements) based on plant extracts, to relieve joint pain.

Bades with plant extracts are concentrated sources of bioactive compounds obtained from plants, which are believed to have anti -inflammatory, analgesic and chondroprotective properties. They are available in various forms, including capsules, tablets, powders and fluids. It is important to note that dietary supplements are not medicines and are not intended for the diagnosis, treatment or prevention of diseases. Nevertheless, they can play an auxiliary role in a comprehensive approach to the control of pain in the joints.

II. Plant extracts with proven effectiveness in joint pain

A number of plant extracts were studied for their potential benefits for joint pain. Some of the most promising include:

A. Kurkuma (Curcuma long)

Turmeric is a plant of a ginger family, known for its powerful anti -inflammatory and antioxidant effects. The active component of turmeric is Kurkumin, which, as shown, inhibits the activity of inflammatory enzymes, such as cyclooxygenase-2 (COO-2) and lipoxygenase (log).

• The mechanism of action: Kurkumin acts on various molecular targets involved in the inflammatory process, including NF-κB, factor of tumor-alpha necrosis (FINED) and interleukins (IL-1, IL-6). It also helps to reduce oxidative stress, protecting the cells from damage caused by free radicals.
• Clinical research: Numerous clinical studies have shown that Kurkumin can be effective in facilitating pain, reducing stiffness and improving the function of joints in people with osteoarthritis. The meta-analyzes of randomized controlled studies (RCTs) confirmed that Kurkumin can be as effective as NSAIDs in a decrease in pain in osteoarthritis, but with fewer side effects.
• Bioavailability: Kurkumin has low bioavailability, which means that it is poorly absorbed in the intestines. To improve absorption, curcumin is often combined with piperin, a component of black pepper, which inhibits enzymes that destroy curcumin in the liver. There are also liposomal and micellar forms of curcumin, which have increased bioavailability.
• Dosage: The recommended dosage of curcumin varies depending on the form and concentration. It is usually recommended to take 500-2000 mg of curcumin per day, divided into several tricks.

B. Ginger (Zingiber Officinale)

Ginger is a widely used spice with a long -standing history of application in traditional medicine. It has anti -inflammatory, analgesic and antioxidant properties.

• The mechanism of action: Ginger contains active compounds, such as gingorols and shogaolas, which inhibit the synthesis of prostaglandins, inflammatory mediators involved in the development of pain. It can also reduce the activity of the COX-2 and the log.
• Clinical research: Studies have shown that ginger can be effective in relief of pain in osteoarthritis, rheumatoid arthritis and muscle pain after physical exercises. The meta-analysis of RCT showed that ginger can significantly reduce the pain with osteoarthritis of the knee joint.
• Forms: Ginger is available in various forms, including fresh root, powder, capsules and oil.
• Dosage: The recommended ginger dosage varies depending on the form. It is usually recommended to take 1-3 grams of fresh ginger per day or 250-1000 mg of ginger extract per day.

C. Boswellia serrata)

Boswellia is a tree growing in India and in the Middle East. Its resin contains bosvelic acids that have powerful anti -inflammatory properties.

• The mechanism of action: Bosvevelic acids inhibit 5-lipoxygenase (5 -og), an enzyme involved in the synthesis of leukotrienes, inflammatory mediators, which play a role in the development of arthritis. They can also suppress the activity of FNI α and IL-1.
• Clinical research: Studies have shown that Boswellion can be effective in relief of pain, reducing stiffness and improving the function of joints in people with osteoarthritis and rheumatoid arthritis. RCT showed that Boswellion can be as effective as NSAIDs in a decrease in pain in osteoarthritis, but with fewer side effects.
• Forms: Boswellia is available in the form of capsules, tablets and creams.
• Dosage: The recommended bosvellia dosage varies depending on the concentration of bosvelic acids. It is usually recommended to take 300-500 mg of Boswellial extract, standardized in content of bosvelic acids, two to three times a day.

D. White willow bark (Salix alba)

The crust of white willow contains sallicin, which is the predecessor of aspirin. Salitsin has painkillers and anti -inflammatory properties.

• The mechanism of action: Salitsin turns into salicylic acid in the body, which inhibits the TsOS-1 and COO-2, enzymes involved in the synthesis of prostaglandins.
• Clinical research: Studies have shown that the bark of white willow can be effective in relief of pain in osteoarthritis, back pain and headaches.
• Side effects: The bark of white willow can cause side effects similar to aspirin, including stomach disorder, heartburn and increased risk of bleeding. It should not be taken with allergies to aspirin or with blood coagulation disorders.
• Dosage: The recommended dosage of the bark of white willow varies depending on the content of salicycle. It is usually recommended to take 60-240 mg of salicycle per day.

E. Devil’s claw (Harpagophytum Procambens)

The devilish claw is a plant growing in South Africa. Its roots contain iridoid glycosides that have anti -inflammatory and analgesic properties.

• The mechanism of action: The devilish claw can inhibit the synthesis of prostaglandins and leukotrienes, as well as suppress the activity of the FZ-α.
• Clinical research: Studies have shown that the devilish claw can be effective in relief of pain in osteoarthritis, back pain and headaches. The meta-analysis of the RCT showed that the devilish claw can significantly reduce the pain with osteoarthritis of the knee and hip joints.
• Side effects: The devilish claw can cause side effects, such as stomach disorder, nausea and diarrhea. It should not be taken by people with an ulcer of the stomach or duodenum.
• Dosage: The recommended dosage of the devilish claw varies depending on the content of iridoid glycosides. It is usually recommended to take 50-100 mg of iridoid glycosides per day.

F. Avocado and SOI Extract of ASU (ASU)

ASU is a mixture of avocado and soy extracts, which are subjected to the non -humiliating process. ASU has chondroprotective and anti -inflammatory properties.

• The mechanism of action: ASU stimulates the synthesis of collagen and proteoglycans, the main components of cartilage. He also inhibits enzymes that destroy cartilage, such as collagenase and stromelizine. In addition, ASU has an anti-inflammatory effect, inhibiting the activity of FZ -α and IL-1.
• Clinical research: Studies have shown that ASU can be effective in relief of pain, reducing stiffness and improving the function of joints in people with osteoarthritis of the knee and hip joints.
• Safety: ASU is usually well tolerated.
• Dosage: The recommended ASU dosage is 300 mg per day.

G. Rosa Canina (Rosa Canina)

Rose Kanin, or Rosehip, is a rich source of vitamin C and antioxidants. It also contains galactolipids that have anti -inflammatory properties.

• The mechanism of action: Galactolipids inhibit the migration of leukocytes into the focus of inflammation and reduce the activity of inflammatory enzymes.
• Clinical research: Studies have shown that a canine rose can be effective in facilitating pain, reducing stiffness and improving the function of joints in people with osteoarthritis and rheumatoid arthritis.
• Safety: Rosa Kanina is usually well tolerated.
• Dosage: The recommended dosage of the canine rose extract varies depending on the content of galactolipids. It is usually recommended to take 2.5-5 grams of canine rose powder per day.

III. Other plant extracts used for joint pain

In addition to the above, there are other plant extracts that are traditionally used to relieve joint pain, although scientific evidence of their effectiveness may be less:

• Dioxa nettle (urtica dioica): It has anti -inflammatory and analgesic properties.
• Cat Claw (Uncaria Tomentosa): It has immunomodulating and anti -inflammatory properties.
• Black currant leaves (Ribes Nigrum): They contain anthocyans that have antioxidant and anti -inflammatory properties.
• Sables of the Swamp (Comarum Palustre): It has anti -inflammatory and analgesic properties.

IV. The importance of quality and safety of dietary supplements

When choosing dietary supplements with plant extracts to relieve joint pain, it is extremely important to take into account the quality and safety of products. Bades are not subject to the same strict regulation as drugs, so the quality and composition can vary significantly.

A. Factors that should be taken into account when choosing dietary supplements:

• Reliable manufacturer: Choose dietary supplements from well -known and reliable manufacturers who adhere to proper production practice (GMP).
• Friendly testing: Look for dietary supplements that have passed third -party testing, efficiency and safety. This guarantees that the product contains the declared ingredients in the indicated quantities and does not contain pollutants.
• Certification: Pay attention to certification from independent organizations such as NSF International, USP or Consumerlab.com.
• Composition: Carefully study the composition of the product to make sure that it contains the desired plant extracts in effective dosages.
• Reviews: Read the reviews of other users to get an idea of ​​the efficiency and safety of the product.
• Consultation with a doctor: Consult a doctor or a qualified medical worker before starting taking any dietary supplements, especially if you have any basic diseases or take other medicines.

B. Potential risks and side effects:

Although plant extracts are usually considered safe, they can cause side effects in some people. Some plant extracts can interact with drugs, so it is important to consult a doctor before taking them, especially if you take anticoagulants, antipassions or immunosuppressants.

Possible side effects of dietary supplements with plant extracts include:

• Indigestion
• Nausea
• Diarrhea
• Allergic reactions
• Interaction with drugs

V. An integrative approach to joint pain

Bades with plant extracts can be a useful addition to a comprehensive approach to joint pain. However, it is important to remember that they are not a replacement for traditional medical treatment.

An integrative approach to joint pain may include:

• Medication: NSAIDs, analgesics, corticosteroids (as prescribed by a doctor).
• Physiotherapy: Exercises to strengthen muscles, improve joint mobility and reduce pain.
• Ergotherapy: Adaptation of the environment and the use of auxiliary devices to facilitate everyday activity.
• Weight loss: Reducing the load on the joints, especially the knee and hip.
• Diet: The use of anti-inflammatory products, such as fruits, vegetables, fish, rich omega-3 fatty acids, and restriction of consumption of treated foods, sugar and saturated fats.
• Alternative treatment methods: Acupuncture, massage, yoga, tai-chi.
• Bades with plant extracts: As an auxiliary agent to relieve pain and inflammation.

VI. Conclusion

Bades with plant extracts can be a valuable addition to a comprehensive plan for treating joint pain. It is important to remember that the results can vary from person to person. Consider the possibility of consulting with a medical worker before starting to receive any new additives in order to verify their safety and compliance with your individual needs. Always choose quality products from reliable manufacturers. Take the solution of the problem of pain in the joints comprehensively, including diet, exercises and other treatment methods to achieve the best results.