New dietary supplements for the joints in the market

New dietary supplements for the joints in the market: a complete review, scientific analysis and prospects

I. New generation chondroprotectors: rethinking classics

1. Glucosamine and chondroitin: improved formulas and combinations

   a. Glucosamine sulfate against glucosamine hydrochloride (HCL): bioavailability and effectiveness. The study of bioavailability of glucosamine sulfate compared to glucosamine hydrochloride. A meta-analysis of studies that compare the effectiveness of various forms of glucosamine in relief of pain and improving the mobility of the joints. An overview of the influence of a sulfate group on absorption and metabolism of glucosamine. Pharmacokinetic studies that demonstrate differences in the concentration of glucosamine in synovial fluid after taking various forms. Clinical studies that evaluate the effect of glucosamine sulfate on a slowdown in the progression of osteoarthritis compared to HCl glucosamine.

   b. Chondroitin sulfate: low molecular weight and high molecular weight. The degree of sulfate. Analysis of differences between low molecular weight and high molecular weight chondroitin sulfate. A review of the influence of molecular mass on the penetration of chondroitin sulfate into cartilage tissue. Discussion of the degree of sulfate of chondroitin sulfate and its influence on biological activity. Scientific data on the role of chondroitin sulfate in the inhibiting of matrix metalloproteinase (MMP) that destroy cartilage. Clinical trials comparing the effectiveness of various molecular masses and degrees of chondroitin sulfate sulfate in reducing pain and improving joint function. Studies that evaluate the effects of chondroitin sulfate on the synthesis of proteoglycans and collagen in cartilage cells.

   c. Synergy of glucosamine and chondroitin: scientific justification of the combination. The study of the synergistic effect of glucosamine and chondroitin in improving joint health. Mechanisms of interaction between glucosamine and chondroitin at the cellular level. Analysis of studies that demonstrate the superiority of combined therapy with glucosamine and chondroitin over monotherapy in reducing pain and inflammation in osteoarthritis. An overview of the influence of a combination of glucosamine and chondroitin on structural changes in cartilage, such as increasing the thickness of the cartilage and a decrease in cartilage defects. Assessment of safety and tolerance of combination therapy with glucosamine and chondroitin.

   d. Innovative forms of delivery: liposomes, nanoparticles, microcapsules. Description of new technologies for the delivery of glucosamine and chondroitin, such as liposomes, nanoparticles and microcapsules. The advantages of using these technologies to increase bioavailability and targeted delivery of chondroprotectors to the joints. Studies that demonstrate improved penetration of chondroprotectors into cartilaginous tissue when using liposomal or nanistisic delivery. Assessment of the stability and effectiveness of these innovative forms of delivery in vitro and in vivo. Clinical studies that evaluate the influence of new forms of glucosamine and chondroitin to reduce pain, improve the function of the joints and slow down the progression of osteoarthritis.

   e. Clinical research and meta analysis: objective assessment of effectiveness. A review of current clinical studies and meta-analyzes that evaluate the effectiveness of glucosamine and chondroitin in osteoarthritis. Analysis of factors affecting research results, such as dosage, duration of treatment, stage of the disease and characteristics of patients. Discussion of conflicting research results and the need for further research to clarify the role of glucosamine and chondroine in the treatment of osteoarthritis. Analysis of the effect of various protocols of treatment with glucosamine and chondroitin on clinical outcomes. Assessment of the economic efficiency of glucosamine and chondroitin in the treatment of osteoarthritis.

2. Methyl sulfonylmetatan (MSM): sulfur for the health of the joints.

   a. MSM action mechanism: anti -inflammatory effect and synthesis of collagen. Description of the mechanism of action of methyl sulfonylmetan (MSM) in the body. The role of MSM in a decrease in inflammation and joint pain. The effect of MSM on the synthesis of collagen, the main component of cartilage. Studies that demonstrate the antioxidant properties of MSM and its ability to protect cartilage cells from damage to free radicals. An overview of the influence of MSM on the immune system and its role in the modulation of an inflammatory response.

   b. MSM in combination with glucosamine and chondroitin: synergistic effect. The study of the synergistic effect of MSM in combination with glucosamine and chondroitin. Analysis of studies demonstrating the superiority of combined MSM therapy, glucosamine and chondroitin over monotherapy in reduction in pain and improving joint function. Discussion of mechanisms through which MSM enhances the effect of glucosamine and chondroitin. Clinical studies that evaluate the influence of the combination of MSM, glucosamine and chondroitin on structural changes in cartilage.

   c. Safety and side effects of MSM: dosage and duration of admission. Assessment of safety and tolerance of MSM. Review of possible side effects of MSM and precautions. Recommendations for the dosage and duration of MSM. Studies that evaluate the influence of MSM on the function of the liver and kidneys. Analysis of the interaction of MSM with other drugs.

   d. Clinical research of MSM: results and prospects. A review of current clinical studies that evaluate the effectiveness of MSM for osteoarthritis and other joint diseases. Analysis of the results of studies demonstrating a decrease in pain, improvement of joint function and decrease in inflammation when taking MSM. Discussion of the prospects for the use of MSM as a component of the complex therapy of joint diseases. Meta-analyzes that evaluate the efficiency and safety of MSM in osteoarthritis.

3. Non-unauthorized type II collagen (UC-II): an innovative approach to the treatment of osteoarthritis.

   a. UC-II action mechanism: immunomodulation and tolerance to collagen. Description of the mechanism of action of the non-reinvented type II collagen (UC-II) in the body. The role of UC-II in immunomodulation and the development of oral tolerance to collagen. An explanation of how UC-II helps reduce an autoimmune attack on cartilage tissue with osteoarthritis. Studies demonstrating the influence of UC-II on the regulation of immune cells, such as T cells and B cells. Overview of the influence of UC-II on the synthesis of anti-inflammatory cytokines.

   b. UC-II against glucosamine and chondroitin: Comparative effectiveness. Comparison of UC-II effectiveness with glucosamine and chondroitin in the treatment of osteoarthritis. Analysis of studies demonstrating the superiority of UC-II over glucosamine and chondroitin in reducing pain and improving joint function. Discussion of the advantages of UC-II in terms of dosage and reception frequency. Clinical studies that evaluate the influence of UC-II on structural changes in cartilage.

   c. UC-II dosage and safety: recommendations and warnings. Recommendations for the dosage of UC-II. Safety and tolerance assessment UC-II. A review of possible side effects UC-II and precautions. Studies that evaluate the influence of UC-II on the function of the liver and kidneys. Analysis of the interaction of UC-II with other drugs.

   d. Clinical studies UC-II: promising results. A review of current clinical studies that evaluate the effectiveness of UC-II in osteoarthritis and other joint diseases. Analysis of the results of studies demonstrating a decrease in pain, improvement of joint function and a decrease in inflammation when taking UC-II. Discussion of the prospects for using UC-II as a component of the complex therapy of joint diseases. Meta-analyzes that evaluate the effectiveness and safety of UC-II in osteoarthritis.

II. Plant extracts and antioxidants: natural support for joints

1. Curcumin: powerful anti -inflammatory agent.

   a. The mechanism of action of turcuminal: inhibiting inflammatory pathways. Description of the mechanism of action of curcumin in the body. The role of curcumin in inhibiting the inflammatory pathways, such as NF-q and COX-2. An explanation of how curcumin helps reduce pain and inflammation in the joints. Studies that demonstrate the antioxidant properties of curcumin and its ability to protect cartilage cells from damage to free radicals. An overview of the influence of Kurkumin on the immune system and its role in the modulation of an inflammatory response.

   b. Bioavailability of curcumin: improved formulas and combinations (piperin, liposomes). Discussion of the problem of low bioavailability of turcumin and ways to solve it. Description of the improved Kurkumin formulas, such as kurkumin with piperin, liposomal curcumin and tarred -shaped micelle form. An explanation of how these formulas increase the absorption and absorption of turskumin in the body. Comparison of the bioavailability of various forms of curcumin.

   c. Kurkumin for osteoarthritis: clinical research and results. A review of clinical studies that evaluate the effectiveness of turcumin in osteoarthritis. Analysis of the results of studies demonstrating a decrease in pain, improvement of joint function and a decrease in inflammation when taking curcumin. A comparison of the effectiveness of turcumin with non -steroidal anti -inflammatory drugs (NSAIDs) in the treatment of osteoarthritis. Meta-analyzes that evaluate the effectiveness and safety of turcumin in osteoarthritis.

   d. Kurkumin and other plant extracts: synergistic effect. The study of the synergistic effect of curcumin in combination with other plant extracts, such as Boswellia, ginger and green tea. Analysis of studies that demonstrate the superiority of combined therapy with turmeric and other plant extracts over monotherapy in reducing pain and inflammation in osteoarthritis. Discussion of the mechanisms through which curcumin enhances the effect of other plant extracts.

2. Boswellia serrata: anti -inflammatory resin extract of incense.

   a. Boswellia action mechanism: inhibiting leukotrienes and 5 -lox. Description of the mechanism of action of Boswellion in the body. The role of Boswellion in the inhibiting of leukotrienes and 5-lipoxygenase (5-Lox), key inflammation factors. An explanation of how Boswellion helps reduce pain and inflammation in the joints. Studies that demonstrate the antioxidant properties of Boswellia and its ability to protect cartilage cells from damage to free radicals. An overview of the influence of Boswellion on the immune system and its role in the modulation of an inflammatory response.

   b. Boswellion and Osteoarthritis: clinical research and results. A review of clinical studies that evaluate the effectiveness of Boswellion with osteoarthritis. Analysis of the results of studies demonstrating a decrease in pain, improvement of joint function and a decrease in inflammation when taking Boswellion. Comparison of the effectiveness of Boswellia with non -steroidal anti -inflammatory drugs (NSAIDs) in the treatment of osteoarthritis. Meta-analyzes that evaluate the efficiency and safety of Boswellion with osteoarthritis.

   c. Boswellion safety and side effects: dosage and duration of admission. Bosvellia security and tolerance assessment. A review of the possible side effects of bosvellia and precautions. Recommendations for the dosage and duration of the bosvellia. Studies that evaluate the influence of Boswellion on the function of the liver and kidneys. Analysis of the interaction of Boswellia with other drugs.

   d. Standardization of Boswellial extracts: The importance of AKBA content (AKBA). Discussion of the importance of standardization of Boswellial extracts on the content of bosvellic acids, especially AKBA (acetyl-Cuto-Bota-boswellic acid). An explanation of how the standardization of extracts provides stable and predictable efficiency. Comparison of various extracts of Boswellion in the content of AKBA and their impact on clinical results.

3. Ginger (Ginger): a traditional remedy for inflammation and pain.

   a. Ginger action mechanism: COX and LOX inhibiting. Description of the mechanism of action of ginger in the body. The role of ginger in inhibiting cyclooxygenase (COX) and lipoxygenase (LOX), enzymes involved in inflammation. An explanation of how ginger helps reduce pain and inflammation in the joints. Studies that demonstrate the antioxidant properties of ginger and its ability to protect cartilage cells from damage to free radicals. An overview of the impact of ginger on the immune system and its role in the modulation of an inflammatory response.

   b. Ginger for osteoarthritis: clinical research and results. A review of clinical studies that evaluate the effectiveness of ginger with osteoarthritis. Analysis of research results demonstrating a decrease in pain, improving joint function and reduction of inflammation when taking ginger. Comparison of ginger effectiveness with non -steroidal anti -inflammatory drugs (NSAIDs) in the treatment of osteoarthritis. Meta-analyzes that evaluate the efficiency and safety of ginger with osteoarthritis.

   c. Forms of ginger: extracts, powder, butter. Discussion of various forms of ginger used in addition, such as extracts, powder and oil. Comparison of the effectiveness of various forms of ginger. The explanation of how ginger extracts standardized in terms of gingerols and shogaols provide more stable and predictable efficiency.

   d. Safety and side effects of ginger: dosage and warnings. Evaluation of safety and tolerance of ginger. Review of possible side effects of ginger and precautions. Recommendations for the dosage of ginger. Studies that evaluate the effect of ginger on the function of the gastrointestinal tract. Analysis of ginger interaction with other drugs.

4. Green tea (Green Tea): antioxidant protection for joints.

   a. The mechanism of action of green tea: polyphenols and EGCG (EGCG). Description of the mechanism of action of green tea in the body. The role of polyphenols and epallocatechin-3-llat (EGCG) in antioxidant protection and reduction of inflammation. An explanation of how green tea helps to protect cartilage cells from damage to free radicals. Studies demonstrating the effects of green tea on matrix metal proproteinase (MMP), destroying cartilage. An overview of the influence of green tea on the immune system and its role in the modulation of an inflammatory response.

   b. Green tea and osteoarthritis: clinical research and results. A review of clinical studies that evaluate the effectiveness of green tea in osteoarthritis. Analysis of research results demonstrating a decrease in pain, improvement of joint function and decrease in inflammation when taking green tea. Discussion of prospects for using green tea as a component of the prevention and treatment of osteoarthritis.

   c. Safety and side effects of green tea: dosage and warnings. Safety and tolerance assessment of green tea. Review of possible side effects of green tea and precautions. Recommendations for the dosage of green tea. Studies that evaluate the effect of green tea on the function of the liver and kidneys. Analysis of the interaction of green tea with other drugs.

5. Garpagophytum (Harpagophytum Procambens): «The Claw of the Devil» to relieve pain.

   a. The mechanism of action of harpagophytum: anti -inflammatory and analgesic effect. Description of the mechanism of the action of harpaggofitum in the body. The role of harpagoside, the main active component of the harpagofitum, in the anti -inflammatory and analgesic effect. An explanation of how harpagophatum helps reduce pain and inflammation in the joints. Studies that demonstrate the influence of harpaggofitum on the synthesis of prostaglandins, inflammation mediators.

   b. Garpagofitum for osteoarthritis: clinical research and results. A review of clinical studies that evaluate the effectiveness of harpagotum in osteoarthritis. Analysis of the results of studies demonstrating a decrease in pain, improvement of joint function and a decrease in inflammation when taking harpagofitum. Comparison of the effectiveness of harpagoofitum with non -steroidal anti -inflammatory drugs (NSAIDs) in the treatment of osteoarthritis. Meta-analyzes that evaluate the efficiency and safety of harpagofitum in osteoarthritis.

   c. Safety and side effects of garpagofitum: dosage and warnings. Assessment of safety and tolerance of harpagofitum. Review of possible side effects of harpagotum and precautions. Recommendations for the dosage of the harpagofitum. Studies that evaluate the effects of harpaggofitum on the function of the gastrointestinal tract. Analysis of the interaction of garpagofitum with other drugs. Contraindications to the use of harpagotum.

III. Vitamins and minerals: indispensable components for joint health

1. Vitamin D: regulation of inflammation and bone health.

   a. The role of vitamin D in bone metabolism and inflammation. Description of the role of vitamin D in bone metabolism and regulation of inflammation. An explanation of how vitamin D helps maintain bone strength and reduce the risk of osteoporosis. Studies demonstrating the influence of vitamin D on the immune system and its role in the modulation of an inflammatory response. An overview of the influence of vitamin D on the synthesis of anti -inflammatory cytokines.

   b. Vitamin D and osteoarthritis: clinical research and results. A review of clinical studies that evaluate the relationship between vitamin D level and the risk of development and progression of osteoarthritis. Analysis of the results of studies that demonstrate the benefits of taking vitamin D to reduce pain and improve joint function in patients with osteoarthritis. Recommendations for screening vitamin D deficiency in patients with joint diseases.

   c. Vitamin D dosage: recommendations and warnings. Recommendations for the dosage of vitamin D to maintain the health of bones and joints. Discussion of various forms of vitamin D, such as vitamin D2 (ergocalciferol) and vitamin D3 (cholegalciferol). Vitamin D safety assessment assessment and overview of possible side effects of vitamin D during an overdose. Analysis of the interaction of vitamin D with other drugs.

2. Vitamin K2: maintaining the health of cartilage and bones.

   a. The role of vitamin K2 in carboxylation of osteocalcine and MGP. Description of the role of vitamin K2 in carboxylation of osteocalcine and matrix GLA-white (MGP), proteins involved in bone metabolism and cartilage. An explanation of how vitamin K2 helps maintain bone strength and prevents cartilage calcification. Studies demonstrating the effects of vitamin K2 on the synthesis of collagen and proteoglycans in cartilage cells.

   b. Vitamin K2 and osteoarthritis: clinical research and results. A review of clinical studies that evaluate the relationship between vitamin K2 level and the risk of development and progression of osteoarthritis. Analysis of the results of studies that demonstrate the benefits of taking vitamin K2 to maintain the health of cartilage and bones in patients with osteoarthritis.

   c. Vitamin K2 dosage: recommendations and warnings. Recommendations for the dosage of vitamin K2 to maintain the health of bones and joints. Discussion of various forms of vitamin K2, such as Menakhinon-4 (MK-4) and Menakhinon-7 (MK-7). Safety and tolerance assessment of vitamin K2. Review of possible side effects of vitamin K2. Analysis of the interaction of vitamin K2 with anticoagulants, such as warfarin.

3. Magnesium: support for muscle function and reduction in pain.

   a. The role of magnesium in muscle function, nervous transmission and inflammation. Description of the role of magnesium in muscle function, nervous transmission and regulation of inflammation. An explanation of how magnesium helps reduce muscle cramps and pain associated with osteoarthritis. Studies demonstrating the effect of magnesium on the synthesis of nitrogen oxide (NO), which is involved in the regulation of blood circulation and inflammation. An overview of the influence of magnesium on the immune system and its role in the modulation of an inflammatory response.

   b. Magnesium and osteoarthritis: clinical research and results. A review of clinical studies that evaluate the relationship between magnesium level and the risk of development and progression of osteoarthritis. Analysis of research results that demonstrate the benefits of taking magnesium to reduce pain and improve joint function in patients with osteoarthritis.

   c. Forms of magnesium: citrate, oxide, glycinate. Bioavailability. Discussion of various forms of magnesium used in addition, such as citrate, oxide and glycinate. Comparison of bioavailability of various forms of magnesium. An explanation of how citrate and glycinate of magnesium have higher bioavailability compared to magnesium oxide.

   d. Magnesium dosage: recommendations and warnings. Recommendations for the dosage of magnesium to maintain the health of bones and joints. Magnesium security and tolerance assessment. A review of possible side effects of magnesium during an overdose, such as diarrhea. Analysis of the interaction of magnesium with other drugs.

4. Zinc: collagen synthesis and immune function.

   a. The role of zinc in the synthesis of collagen, immune function and antioxidant protection. Description of the role of zinc in the synthesis of collagen, immune function and antioxidant protection. An explanation of how zinc helps to maintain the structure and function of cartilage. Studies demonstrating the influence of zinc on the activity of enzymes involved in the synthesis of collagen. An overview of the influence of zinc on the immune system and its role in the modulation of an inflammatory response.

   b. Zinc and osteoarthritis: clinical research and results. A review of clinical studies that evaluate the relationship between zinc level and the risk of development and progression of osteoarthritis. Analysis of the results of studies that demonstrate the benefits of taking zinc to maintain joint health in patients with osteoarthritis.

   c. Forms of zinc: citrate, gluconate, picoline. Bioavailability. Discussion of various forms of zinc used in addition, such as citrate, gluconate and picoline. Comparison of bioavailability of various forms of zinc. An explanation of how a zinc picolinate has a higher bioavailability compared to other zinc forms.

   d. Zinc dosage: recommendations and warnings. Recommendations for the dosage of zinc to maintain the health of bones and joints. Evaluation of security and tolerance of zinc. A review of possible side effects of zinc during an overdose, such as nausea and vomiting. Analysis of zinc interaction with other minerals, such as copper.

5. Selenium: antioxidant protection and reduction of inflammation.

   a. The role of selenium in antioxidant protection and thyroid function. Description of the role of selenium in antioxidant protection and thyroid function. An explanation of how selenium helps to protect cartilage cells from damage to free radicals. Studies demonstrating the influence of selenium on the activity of glutathioneperoxidase, key antioxidant enzyme. A review of Selena’s influence on the immune system and its role in the modulation of an inflammatory response.

   b. Selenium and osteoarthritis: clinical research and results. A review of clinical studies that evaluate the relationship between selenium level and the risk of development and progression of osteoarthritis. Analysis of the results of studies that demonstrate the benefits of taking selenium to maintain joint health in patients with osteoarthritis.

   c. Selena’s forms: selenometyonin, selenite. Bioavailability. Discussion of various forms of selenium used in additions, such as selenometyonin and selenite. Comparison of bioavailability of various forms of selenium. An explanation of how selenometyonin has a higher bioavailability compared to selenite.

   d. Selena dosage: recommendations and warnings. Recommendations for the dosage of Selena to maintain the health of bones and joints. Evaluation of the security and tolerance of selenium. A review of possible side effects of selenium during an overdose, such as hair loss and skin lesion. Analysis of selenium interaction with other minerals.

IV. Omega-3 fatty acids: anti-inflammatory support for joints

1. Omega-3 action mechanism: inhibiting inflammation and synthesis of resolvines.

   a. The role of EPK (EPA) and DGK (DHA) in inhibiting inflammation. Description of the role of eicopascentaenic acid (EPK) and non-achexaenic acid (DGC), the main omega-3 fatty acids, in inhibiting inflammation. An explanation of how EPK and DGC help reduce the synthesis of inflammatory prostaglandins and leukotrienes. Studies demonstrating the influence of EPC and DGC on the immune system and their role in the modulation of an inflammatory response. An overview of the influence of EPC and DGK on the synthesis of anti -inflammatory resolvines and protectins.

   b. Omega-3 and osteoarthritis: clinical research and results. A review of clinical studies that evaluate the effectiveness of omega-3 fatty acids for osteoarthritis. Analysis of the results of studies demonstrating a decrease in pain, improvement of joint function and a decrease in inflammation when taking omega-3 fatty acids. Comparison of the effectiveness of omega-3 fatty acids with non-steroidal anti-inflammatory drugs (NSAIDs) in the treatment of osteoarthritis. Meta-analyzes that evaluate the effectiveness and safety of omega-3 fatty acids in osteoarthritis.

   c. Sources of Omega-3: Fish oil, Krill oil, plant springs (Alk). Discussion of various sources of omega-3 fatty acids, such as fish oil, crill oil and plant sources (alpha-linolenic acid-Alk). Comparison of the bioavailability and effectiveness of EPC and DGC from various sources. An explanation of how fish oil and krill oil are directly contained by EPC and DGK, while the ALK should be transformed into EPC and DGK in the body, which is a less effective process.

   d. Omega-3 dosage: recommendations and warnings. Recommendations for the dosage of omega-3 fatty acids to maintain the health of bones and joints. Omega-3 fatty safety and tolerance assessment. A review of the possible side effects of omega-3 fatty acids, such as fishing and liquefaction of blood. Analysis of the interaction of omega-3 fatty acids with anticoagulants, such as warfarin.

V. Peptides and amino acids: new horizons in support of the joints

1. Collagen peptides: building blocks for cartilage.

   a. The mechanism of action of collagen peptides: stimulation of collagen synthesis. Description of the mechanism of action of collagen peptides in the body. An explanation of how collagen peptides stimulate collagen synthesis in cartilage cells. Studies demonstrating the influence of collagen peptides on increasing the thickness of the cartilage and improving its structure. An overview of the influence of collagen peptides on the synthesis of proteoglycans, the main components of cartilage.

   b. Collagen peptides and osteoarthritis: clinical studies and results. A review of clinical studies that evaluate the effectiveness of collagen peptides in osteoarthritis. Analysis of the results of studies demonstrating a decrease in pain, improvement of joint function and a decrease in inflammation when taking collagen peptides. Discussion of the prospects for using collagen peptides as a component of the complex therapy of joint diseases. Meta-analyzes that evaluate the effectiveness and safety of collagen peptides in osteoarthritis.

   c. Various types of collagen peptides: type I, type II, type III. Discussion of various types of collagen peptides, such as type I, type II and type III. Comparison of the effectiveness of various types of collagen peptides depending on their origin and amino acid composition. The explanation is that type II collagen peptides are more specific for cartilage.

   d. Dosage of collagen peptides: recommendations and warnings. Recommendations for the dosage of collagen peptides to maintain the health of bones and joints. Assessment of safety and tolerance of collagen peptides. Review of possible side effects of collagen peptides. Analysis of the interaction of collagen peptides with other additives.

2. L-Prollyn and L Lizin: Amino acids for collagen synthesis.

   a. The role of L-Proline and L-lysine in the synthesis of collagen. Description of the role of L-Prolin and L-lysine, amino acids, in the synthesis of collagen. An explanation of how L-Prollyn and L Lizin are necessary for the formation of a stable structure of collagen. Studies demonstrating the influence of L-Proline and L-lysine on the synthesis of hydroxyproline and hydroxylizin, modified amino acids important for the strength of collagen.

   b. L-Prollyn and L-Lisin and Osteoarthritis: potential advantages. Review of studies that evaluate the potential advantages of taking L-professional and L-lysine for osteoarthritis. Analysis of the results of studies that demonstrate the benefits of taking L-professional and L-lysine to maintain the health of cartilage and bones in patients with osteoarthritis.

   c. Dosage of L-Proline and L-lysine: recommendations and warnings. Recommendations for the dosage of L-Proline and L-lysine to maintain the health of bones and joints. Safety and tolerance assessment of L-Proline and L-lysine. Overview of possible side effects of L-professional and