What dietary supplements will help with arthrosis and arthritis

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What dietary supplements will help with arthrosis and arthritis: a detailed and comprehensive review

Table of contents

  1. Understanding arthrosis and arthritis: Differences, symptoms and causes

    • 1.1. Arthrosis: degenerative joint disease
    • 1.2. Arthritis: inflammatory joint disease
    • 1.3. Differences in the causes and pathogenesis
    • 1.4. Common symptoms of arthrosis
    • 1.5. Common symptoms of arthritis
    • 1.6. Diagnosis Arthrosis and Arthritis

  2. The role of dietary supplements in the complex therapy of arthrosis and arthritis: Opportunities and restrictions

    • 2.1. Additional support, not replacing the main treatment
    • 2.2. Symptoms Management and Improving the quality of life
    • 2.3. Potential slowdown in the progression of the disease
    • 2.4. Individual differences in the effectiveness of dietary supplements
    • 2.5. The importance of consulting a doctor

  3. Key components of dietary supplements to support the joints: Review and mechanisms of action

    • 3.1. Glucosamine: structural element of cartilage fabric
      • 3.1.1. Glucosamine mechanism
      • 3.1.2. Shapes glucosamina: sulfate, hydroxloride, n-acetilcycosamin
      • 3.1.3. Glucosamine dosage
      • 3.1.4. Side effects of glucosamine
      • 3.1.5. Clinical studies of glucosamine
    • 3.2. Chondroitin: water retention and elasticity of cartilage
      • 3.2.1. Chondroitin mechanism
      • 3.2.2. Sources of chondroitin: shark cartilage, cattle
      • 3.2.3. Chondroitin dosage
      • 3.2.4. Side effects of chondroitin
      • 3.2.5. Clinical studies of chondroitin
    • 3.3. MSM (methyl sulfonylmetatan): Sure for joint health
      • 3.3.1. MSM action mechanism
      • 3.3.2. The role of sulfur in collagen synthesis
      • 3.3.3. MSM dosage
      • 3.3.4. Side effects of MSM
      • 3.3.5. Clinical research of MSM
    • 3.4. Collagen: protein for restoration of cartilage fabric
      • 3.4.1. Types of collagen: I, II, III
      • 3.4.2. Type II collagen: specialized for cartilage
      • 3.4.3. Hydrolyzed collagen: easy assimilation
      • 3.4.4. Collagen dosage
      • 3.4.5. Side effects of collagen
      • 3.4.6. Clinical studies of collagen
    • 3.5. Hyaluronic acid: joint lubricant
      • 3.5.1. Hyaluronic acid action mechanism
      • 3.5.2. Intra -articular injections of hyaluronic acid
      • 3.5.3. Oral hyaluronic acid: effectiveness
      • 3.5.4. Dosage of hyaluronic acid
      • 3.5.5. Side effects of hyaluronic acid
      • 3.5.6. Clinical studies of hyaluronic acid
    • 3.6. Omega-3 fatty acids: anti-inflammatory effect
      • 3.6.1. EPA (ecosapentaenic acid) and DGC (docosahexaenic acid)
      • 3.6.2. Omega-3 action mechanism
      • 3.6.3. Sources Omega-3: Fish oil, linseed oil
      • 3.6.4. Omega-3 dosage
      • 3.6.5. Side effects Omega-3
      • 3.6.6. Clinical research Omega-3
    • 3.7. Kurkumin: powerful antioxidant and anti -inflammatory agent
      • 3.7.1. The mechanism of action of turcumumin
      • 3.7.2. Problems with bioavailability of curcumin
      • 3.7.3. Improved forms of curcumin: with piperin, liposomal curcumin
      • 3.7.4. Kurkumin dosage
      • 3.7.5. Side effects of curcumin
      • 3.7.6. Clinical studies of curcumin
    • 3.8. S-adenosylmetionine (SAME): Support for cartilage and pain reduction
      • 3.8.1. Same mechanism
      • 3.8.2. Impact Same of Synthesis Protoglycanov
      • 3.8.3. Dosage Same
      • 3.8.4. Side effects SAME
      • 3.8.5. Clinical research SAME
    • 3.9. Boswellia serrata: Anti -inflammatory properties
      • 3.9.1. The mechanism of action of Boswellia
      • 3.9.2. Active components of Boswellion: Boswellial acids
      • 3.9.3. Dosage
      • 3.9.4. Side effects of Boswellia
      • 3.9.5. Clinical studies of Boswellion
    • 3.10. Vitamin D: The importance of bone health and joints
      • 3.10.1. Vitamin D action mechanism
      • 3.10.2. The influence of vitamin D on inflammation
      • 3.10.3. The optimal level of vitamin D in the blood
      • 3.10.4. Vitamin D dosage
      • 3.10.5. Side effects of vitamin D
      • 3.10.6. Clinical studies of vitamin D

  4. Features of the choice of dietary supplements: What to pay attention to when buying

    • 4.1. The quality of the ingredients and the purity of the product
    • 4.2. Availability of quality certificates (GMP, NSF)
    • 4.3. Reputation
    • 4.4. Release form (capsules, tablets, powders, liquids)
    • 4.5. Dosage and reception scheme
    • 4.6. Interaction with other drugs and dietary supplements
    • 4.7. Individual tolerance and allergic reactions
    • 4.8. Reviews and recommendations of doctors
    • 4.9. Composition: the presence of additional ingredients (vitamins, minerals)
    • 4.10. Best before date

  5. A combination of dietary supplements with other treatment methods: A comprehensive approach

    • 5.1. Physiotherapy: exercises and massage to improve mobility
    • 5.2. Medical physical education (exercise therapy): muscle strengthening and joint stabilization
    • 5.3. Proper nutrition: anti -inflammatory diet
    • 5.4. Weight control: decrease in the load on the joints
    • 5.5. Pharmacological treatment: painkillers, NSAIDs, chondroprotectors
    • 5.6. Injections of corticosteroids and hyaluronic acid
    • 5.7. Alternative methods: acupuncture, acupuncture
    • 5.8. Surgical intervention: endoprosthetics

  6. Anti -inflammatory diet with arthrosis and arthritis: Products that help and harm

    • 6.1. Products useful for joints: fatty fish, olive oil, nuts, seeds, fruits, vegetables
    • 6.2. Products that should be avoided: sugar, treated foods, red meat, alcohol, gluten (for some)
    • 6.3. The importance of sufficient water consumption
    • 6.4. Individual intolerance to products
    • 6.5. The role of dietary fibers in maintaining joint health

  7. Scientific research and evidence base: Review of clinical trials

    • 7.1. Systematic reviews and meta analyzes
    • 7.2. Randomized controlled studies (RCTs)
    • 7.3. Study of efficiency and safety of dietary supplements
    • 7.4. Interpretation of research results: statistical significance and clinical significance
    • 7.5. Dad research restrictions: quality, sample size, financing

  8. Bad for arthrosis: Specific recommendations

    • 8.1. Glucosamine and chondroitin: the basis of cartilage support
    • 8.2. Type II collagen: Restoring the structure of the cartilage
    • 8.3. Hyaluronic acid: improvement of joint lubrication
    • 8.4. MSM: Support for collagen synthesis
    • 8.5. Vitamin D: Bone strengthening

  9. Bad for arthritis: Specific recommendations

    • 9.1. Omega-3 fatty acids: decrease in inflammation
    • 9.2. Kurkumin: powerful anti -inflammatory effect
    • 9.3. Boswellion: suppression of inflammatory processes
    • 9.4. Same: Reducing pain and inflammation
    • 9.5. Probiotics: maintaining a healthy intestinal microflora and a decrease in inflammation

  10. Bad for the elderly: Features of application and dosage

    • 10.1. Age -related changes in metabolism and assimilation of dietary supplements
    • 10.2. Interaction with other drugs
    • 10.3. Increased risk of side effects
    • 10.4. The need to consult a doctor
    • 10.5. Dosage optimization for elderly patients

  11. Bad for athletes: Joint support for intense loads

    • 11.1. Injury prevention and recovery after training
    • 11.2. Acceleration of the restoration of cartilage
    • 11.3. Reduction of inflammation and pain
    • 11.4. Dosages of dietary supplements for athletes
    • 11.5. The importance of balanced nutrition and hydration

  12. Bades with autoimmune diseases: Role in complex therapy (rheumatoid arthritis, psoriatic arthritis)

    • 12.1. Support for the immune system
    • 12.2. Decrease in inflammation
    • 12.3. Improving the quality of life
    • 12.4. Interaction with immunosuppressors
    • 12.5. The need to consult a rheumatologist

  13. Dangerous dietary supplements and fakes: How to avoid fraud

    • 13.1. Unverified ingredients
    • 13.2. Excessed promises
    • 13.3. Lack of information about the manufacturer
    • 13.4. Buying from unofficial distributors
    • 13.5. Signs of fake
    • 13.6. Checking the authenticity of the product

  14. Legal aspects and regulation of dietary supplements: What the consumer needs to know

    • 14.1. Differences in the regulation of dietary supplements in different countries
    • 14.2. Responsibility of the manufacturer
    • 14.3. Consumer rights
    • 14.4. The importance of checking the product information

  15. The future of the dietary supplements for the joints: New developments and prospects

    • 15.1. Nanotechnology in the delivery of dietary supplements
    • 15.2. Personalized approach to the choice of dietary supplements
    • 15.3. The use of artificial intelligence to analyze data and predict effectiveness
    • 15.4. Research in genetic therapy and regenerative medicine

1. Understanding of arthrosis and arthritis: differences, symptoms and causes

It is important to understand the difference between arthrosis and arthritis, since the approaches to treatment, including the use of dietary supplements, may vary.

1.1. Arthrosis: degenerative joint disease

Arthrosis (osteoarthritis) is a chronic degenerative disease characterized by the gradual destruction of cartilage tissue covering the surface of the bones in the joint. Cartoon acts as a shock absorber, providing smooth movement of the joint. With arthrosis, cartilage is thinner and can completely disappear over time, which leads to friction of bones against each other.

1.2. Arthritis: inflammatory joint disease

Arthritis is a common name for a group of diseases characterized by inflammation of one or more joints. There are many types of arthritis, including rheumatoid arthritis (autoimmune disease), osteoarthritis (mentioned above), psoriatic arthritis, gout and others.

1.3. Differences in the causes and pathogenesis

  • Arthrosis: The main cause of arthrosis is the wear of the cartilage over time. Risk factors include age, genetic predisposition, joint injuries, obesity and repeating loads on the joints. The pathogenesis of arthrosis includes the destruction of cartilage, the formation of bone growths (osteophytes) and inflammation.

  • Arthritis: The causes of arthritis depend on the type of disease. Rheumatoid arthritis is an autoimmune disease in which the immune system attacks its own joint tissue. Gout is caused by the accumulation of uric acid crystals in the joints. Infectious arthritis occurs as a result of a bacterial, viral or fungal infection.

1.4. Common symptoms of arthrosis

  • The pain in the joint, which intensifies when moving and subsides at rest
  • Restriction of joint mobility
  • Joints of the joint, especially in the morning or after the period of inaction
  • Crunch or clicks in the joint when moving
  • Swelling and soreness around the joint
  • Education of bone growths (osteophytes)

1.5. Common symptoms of arthritis

  • Joint pain
  • Joint inflammation (edema, redness, heat)
  • The stiffness of the joints, especially in the morning (can last more than 30 minutes)
  • Restriction of joint mobility
  • Fatigue
  • Fever (with some types of arthritis)
  • General malaise

1.6. Diagnosis Arthrosis and Arthritis

Diagnosis of arthrosis and arthritis includes:

  • Medical examination: The doctor evaluates the symptoms, medical history and conducts a physical examination of the joints.
  • X -ray research: Allows you to identify signs of cartilage destruction, osteophytes, and other changes in the joints.
  • Magnetic resonance tomography (MRI): A more detailed study that can show damage to cartilage, ligaments and other soft tissues.
  • Blood tests: They can help identify signs of inflammation, autoimmune diseases or infections.
  • Analysis of synovial fluid: The fluid obtained from the joint can be examined for the presence of uric acid crystals (with gout) or signs of infection.

2. The role of dietary supplements in the complex therapy of arthrosis and arthritis: opportunities and restrictions

Bades (biologically active additives) can play an auxiliary role in the complex therapy of arthrosis and arthritis, but it is important to understand their capabilities and restrictions.

2.1. Additional support, not replacing the main treatment

Bades are not a replacement for standard medical treatment, which may include medicines (painkillers, NSAIDs, chondroprotectors, immunosuppressors), physiotherapy, physiotherapy exercises and, in some cases, surgical intervention. Bades should be considered as an addition to the main treatment aimed at alleviating symptoms and improving the quality of life.

2.2. Symptoms Management and Improving the quality of life

Many dietary supplements used for arthrosis and arthritis have anti -inflammatory and analgesic properties, which can help reduce pain, stiffness and edema in the joints. This, in turn, can improve the mobility of the joints and the quality of the patient’s life.

2.3. Potential slowdown in the progression of the disease

Some studies show that certain dietary supplements, such as glucosamine and chondroitin, can help slow down the progression of arthrosis, protecting cartilage tissue from further destruction. However, these data are not always unambiguous, and additional studies are needed.

2.4. Individual differences in the effectiveness of dietary supplements

The effectiveness of dietary supplements can vary from person to person. What helps one patient may not help another. This is due to the individual characteristics of the body, the severity of the disease, the presence of concomitant diseases and other factors.

2.5. The importance of consulting a doctor

Before taking any dietary supplements, it is necessary to consult a doctor. The doctor will be able to evaluate the patient’s health, take into account possible contraindications and interactions with other medicines, as well as give recommendations for the choice of the most suitable dietary supplements and their dosage.

3. Key components of dietary supplements to support joints: review and mechanisms of action

There are a number of key components of dietary supplements that are often used to support joint health for arthrosis and arthritis. Consider them in more detail:

3.1. Glucosamine: structural element of cartilage fabric

Glucosamine is an aminosaccharide, which is an important building block for cartilage. It is naturally produced in the body and is involved in the synthesis of glycosaminoglycans (GAG), which are the main components of cartilage.

3.1.1. Glucosamine mechanism

Glucosamine stimulates the formation of GAG and proteoglycans, which are necessary to maintain the structure and function of cartilage. It can also have anti -inflammatory properties, suppressing the production of some inflammatory mediators.

3.1.2. Shapes glucosamina: sulfate, hydroxloride, n-acetilcycosamin

There are various forms of glucosamine, the most common are glucosamine sulfate, hydrochloride glucosamine and n-acetylhlucosamine. Glucosamine sulfate is considered the most studied form, and many clinical studies have shown its effectiveness.

3.1.3. Glucosamine dosage

The usually recommended dosage of glucosamine is 1,500 mg per day, divided into several tricks.

3.1.4. Side effects of glucosamine

Glucosamine is usually well tolerated, but some people may have side effects, such as nausea, diarrhea, heartburn and constipation. Glucosamine can affect blood sugar, so people with diabetes should use it with caution.

3.1.5. Clinical studies of glucosamine

Clinical studies of glucosamine showed conflicting results. Some studies have shown that glucosamine can help reduce pain and improve joint function in people with arthrosis, while other studies have not revealed a significant effect.

3.2. Chondroitin: water retention and elasticity of cartilage

Chondroitin is glycosaminoglican, which is also an important component of cartilage. It helps the cartilage to hold water and maintain elasticity.

3.2.1. Chondroitin mechanism

Chondroitin inhibits enzymes that destroy cartilage and stimulates the production of hyaluronic acid, which is an important component of synovial fluid, lubricating the joints.

3.2.2. Sources of chondroitin: shark cartilage, cattle

Chondroitin is obtained from various sources, including sharks of cartilage and cattle cartilage. It is important to choose products from reliable manufacturers to make sure of their quality and safety.

3.2.3. Chondroitin dosage

The usually recommended chondroitin dosage is 800-1200 mg per day, divided into several tricks.

3.2.4. Side effects of chondroitin

Chondroitin is usually well tolerated, but some people may have side effects, such as nausea, diarrhea and headache. Chondroitin can increase the risk of bleeding, so people taking anticoagulants should use it with caution.

3.2.5. Clinical studies of chondroitin

Clinical studies of chondroitin showed conflicting results, similarly to glucosamine. Some studies have shown that chondroitin can help reduce pain and improve joint function in people with arthrosis, while other studies have not revealed a significant effect.

3.3. MSM (methyl sulfonylmetatan): Sure for joint health

MSM (methyl sulfonylmetatan) is an organic compound of sulfur, which is naturally found in plants, animals and humans. Sure is an important component for many biological processes, including collagen synthesis, which is necessary for joint health.

3.3.1. MSM action mechanism

MSM has anti -inflammatory and antioxidant properties. It can help reduce pain and inflammation in the joints, as well as improve their mobility.

3.3.2. The role of sulfur in collagen synthesis

Sure plays an important role in the formation of disulfide bonds that stabilize the structure of collagen. Collagen is the main structural protein of cartilaginous tissue, so sulfur wealth is important to maintain joint health.

3.3.3. MSM dosage

Usually the recommended dosage of MSM is 1000-3000 mg per day, divided into several techniques.

3.3.4. Side effects of MSM

MSM is usually well tolerated, but some people may have side effects, such as nausea, diarrhea and headache.

3.3.5. Clinical research of MSM

Clinical studies of MSM have shown that it can help reduce pain and improve joint function in people with arthrosis.

3.4. Collagen: protein for restoration of cartilage fabric

Collagen is the main structural protein, which is contained in the skin, bones, tendons, ligaments and cartilage. It provides the strength and elasticity of these tissues.

3.4.1. Types of collagen: I, II, III

There are several types of collagen, but the most common are the types of I, II and III. Type I collagen is found in the skin, bones and tendons. Type II collagen is the main component of cartilage. Type III collagen is found in the skin and blood vessels.

3.4.2. Type II collagen: specialized for cartilage

To support joint health, type II collagen is especially important, since it is the main component of cartilage.

3.4.3. Hydrolyzed collagen: easy assimilation

Hydrolyzed collagen is a collagen that was divided into smaller peptides, which facilitates its absorption by the body.

3.4.4. Collagen dosage

The usually recommended dosage of hydrolyzed collagen is 10-20 grams per day.

3.4.5. Side effects of collagen

Collagen is usually well tolerated, but some people may have side effects, such as nausea, diarrhea and heartburn.

3.4.6. Clinical studies of collagen

Clinical studies of collagen showed that it can help reduce pain and improve joint function in people with arthrosis.

3.5. Hyaluronic acid: joint lubricant

Hyaluronic acid is a natural substance contained in the joint fluid (synovial fluid). It acts as a lubricant, reducing friction between bones in the joint.

3.5.1. Hyaluronic acid action mechanism

Hyaluronic acid helps to improve the viscosity and elasticity of the synovial fluid, which facilitates the movement of the joint and reduces the pain.

3.5.2. Intra -articular injections of hyaluronic acid

Hyaluronic acid can also be administered directly into the joint in the form of injections. This can ensure rapid relief of pain and improving the joint function, but the effect is usually temporary.

3.5.3. Oral hyaluronic acid: effectiveness

There are also dietary supplements with hyaluronic acid for oral use. The effectiveness of oral hyaluronic acid is the subject of discussions, but some studies show that it can help improve cartilage hydration and reduce inflammation.

3.5.4. Dosage of hyaluronic acid

The usually recommended dosage of hyaluronic acid is 100-200 mg per day.

3.5.5. Side effects of hyaluronic acid

Hyaluronic acid is usually well tolerated, but some people may have side effects, such as nausea, diarrhea and headache.

3.5.6. Clinical studies of hyaluronic acid

Clinical studies of hyaluronic acid showed that both intra -articular injections and oral additives can help reduce pain and improve joint function in people with arthrosis.

3.6. Omega-3 fatty acids: anti-inflammatory effect

Omega-3 fatty acids are polyunsaturated fatty acids that have anti-inflammatory properties.

3.6.1. EPA (ecosapentaenic acid) and DGC (docosahexaenic acid)

The most important omega-3 fatty acids for the health of the joints are EPK (eicopascentaenoic acid) and DGK (non-oxaexaic acid).

3.6.2. Omega-3 action mechanism

Omega-3 fatty acids reduce the production of inflammatory mediators, such as prostaglandins and leukotrienes, which can help reduce pain and inflammation in the joints.

3.6.3. Sources Omega-3: Fish oil, linseed oil

The main sources of omega-3 fatty acids are fatty fish (salmon, mackerel, sardines) and linseed oil. Fish oil contains EPK and DGC, and linseed oil contains alpha-linolenic acid (ALK), which can be transformed into EPK and DHC in the body, but this process is not very effective.

3.6.4. Omega-3 dosage

Usually the recommended dosage of omega-3 fatty acids is 1000-3000 mg per day containing at least 500 mg of EPK and DGK.

3.6.5. Side effects Omega-3

Omega-3 fatty acids are usually well tolerated, but some people may have side effects, such as fish taste, nausea, diarrhea and heartburn. Omega-3 fatty acids can increase the risk of bleeding, so people taking anticoagulants should use them with caution.

3.6.6. Clinical research Omega-3

Clinical studies of omega-3 fatty acids showed that they can help reduce pain and inflammation in the joints in people with arthritis.

3.7. Kurkumin: powerful antioxidant and anti -inflammatory agent

Kurkumin is an active substance contained in turmeric, spices widely used in Indian cuisine. Kurkumin has powerful antioxidant and anti -inflammatory properties.

3.7.1. The mechanism of action of turcumumin

Kurkumin inhibits the activity of inflammatory molecules, such as NF-KB and cyclooxygenase-2 (COX-2), which can help reduce pain and inflammation in the joints.

3.7.2. Problems with bioavailability of curcumin

Kurkumin has low bioavailability, which means that it is poorly absorbed by the body.

3.7.3. Improved forms of curcumin: with piperin, liposomal curcumin

To increase the bioavailability of curcumin, it is often combined with piperin, an active substance contained in black pepper. There are also liposomal forms of curcumin, which also have higher bioavailability.

3.7.4. Kurkumin dosage

The usually recommended dosage of curcumin is 500-2000 mg per day, depending on the shape of the product and its bioavailability.

3.7.5. Side effects of curcumin

Kurkumin is usually well tolerated, but some people may have side effects, such as nausea, diarrhea and headache.

3.7.6. Clinical studies of curcumin

Clinical studies of Kurkumin showed that it can help reduce pain and inflammation in the joints in people with arthritis and arthrosis.

3.8. S-adenosylmetionine (SAME): Support for cartilage and pain reduction

S-adenosylmetionine is a natural substance contained in all living cells. It participates in many biochemical processes, including the synthesis of cartilage and neurotransmitters that regulate mood and pain.

3.8.1. Same mechanism

Same is involved in the synthesis of proteoglycans, which are the main components of cartilage. It can also have anti -inflammatory and analgesic properties.

3.8.2. Impact Same of Synthesis Protoglycanov

Same stimulates the synthesis of proteoglycans, which can help restore cartilage tissue and improve the function of the joints.

3.8.3. Dosage Same

Usually recommended same dosage is 200-40

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