Dietrs for the joints: reviews of doctors and buyers
I. Anatomy and joint physiology: brief review
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The main components of the joint:
- Joint cartilage: A hyaline cartilage covering bone surfaces in the joint. Consists of chondrocytes, extracellular matrix (collagen, proteoglycans, hyaluronic acid). Functions: depreciation, friction reduction.
- Synovial fluid: A viscous fluid filling the joint cavity. Contains hyaluronic acid, lubricin. Functions: lubrication, cartilage power, removal of decay products.
- The joint capsule: Fibrous membrane surrounding the joint. Contains ligaments that strengthen the joint. Function: joint stabilization, limitation of the range of movements.
- Blues: Connective tissues connecting bones. Function: joint stabilization, limitation of the range of movements.
- Muscles and tendons: Provide movement in the joint. The tendons connect the muscles to the bones. Function: movement, stabilization.
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Joint cartilage nutrition mechanisms:
- Diffusion: Nutrients from synovial fluid are diffused in cartilage.
- Impiece: Absorption of synovial fluid with cartilage during movement (compression and relaxation).
- Peripheral blood supply: Minor blood supply near the border of cartilage and bone.
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Carthing degeneration processes:
- Reducing the synthesis of proteoglycans: Reducing the content of chondroitin and glucosamine in a cartilage matrix.
- Collagen degradation: The destruction of collagen fibers that ensure the strength of the cartilage.
- Inflammation: The release of inflammatory mediators (cytokines, prostaglandins) in the articular cavity.
- Osteophytic formation: The formation of bone growths (osteophytes) along the edges of the joint.
- Reducing the viscosity of synovial fluid: Reducing the content of hyaluronic acid.
II. The main diseases of the joints:
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Osteoarthritis (osteoarthritis, arthrosis):
- Definition: Chronic degenerative joint disease, characterized by the destruction of cartilage, changes in bone tissue and inflammation.
- Etiology: Age, genetic predisposition, injury, obesity, repeated loads.
- Pathogenesis: Destruction of cartilage, inflammation, osteophytic formation, changes in the subchondral bone.
- Symptoms: Pain, stiffness, limitation of mobility, crunch in the joint, deformation.
- Diagnosis: Radiography, MRI, arthroscopy, synovial analysis.
- Treatment: Painkillers, anti -inflammatory, physiotherapy, physiotherapy exercises, chondroprotectors, hyaluronic acid injections, surgical intervention (endoprosthetics).
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Rheumatoid arthritis:
- Definition: Chronic autoimmune disease affecting joints and other organs.
- Etiology: Unknown, a genetic predisposition and impact of environmental factors is assumed.
- Pathogenesis: Autoimmune reaction, inflammation of the synovial membrane, destruction of cartilage and bone.
- Symptoms: Pain, stiffness (especially morning), swelling of the joints, symmetrical damage, weakness, fatigue.
- Diagnosis: Blood test (rheumatoid factor, antibodies to the cyclic citrollinized peptide – ACCP), radiography, MRI.
- Treatment: Basis therapy (methotrexate, sulfasalazine, leflunomide), biological preparations (FNO inhibitors, IL-6 inhibitors, inhibitors of co-stimulations of T-lymphocytes), painkillers, anti-inflammatory.
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Gout:
- Definition: The disease caused by the deposition of uric acid crystals in the joints and other tissues.
- Etiology: Increased uric acid in the blood (hyperuricemia), a violation of the metabolism of purines.
- Pathogenesis: The deposition of uric acid crystals in the joints, inflammation, destruction of cartilage and bones.
- Symptoms: Sharp attacks of pain, redness, swelling, fever in the affected joint (most often the thumb of the foot), the formation of tofus (uric acid deposits) in the tissues.
- Diagnosis: Blood test (uric acid level), analysis of synovial fluid (detection of uric acid crystals).
- Treatment: Painkillers, anti -inflammatory (colchicin), drugs that reduce uric acid levels (allopurinol, phyubuxostat), diet.
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Other joint diseases:
- Psoriatic arthritis: Inflammatory joint disease associated with psoriasis.
- Reactive arthritis: Joint inflammation, developing after infection.
- Anquilizing spondylitis (Bekhtereva’s disease): Chronic inflammatory disease that affects the spine and sacral-illegal joints.
- System red lupus: Autoimmune disease that affects various organs, including joints.
- Septic arthritis: Joint infection.
III. Dietrs for the joints: an overview of the main components and mechanisms of action
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Glucosamine:
- Description: Aminosaccharide, natural component of cartilage.
- The mechanism of action: Presumably stimulates the synthesis of proteoglycans and hyaluronic acid in cartilage, has an anti -inflammatory effect.
- Forms: Glucosamine sulfate, glucosamine hydrochloride, n-acetylhlucosamine.
- Dosage: Usually 1500 mg per day.
- Side effects: Rarely – dyspepsia, nausea, diarrhea.
- Contraindications: Individual intolerance, pregnancy, lactation.
- Clinical research: The results are contradictory. Some studies show a moderate decrease in pain and improving the function of joints with osteoarthritis, others do not reveal a significant effect. Efficiency may depend on the form of glucosamine and the stage of the disease.
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Chondroitin:
- Description: Glycosaminoglican, natural component of cartilage.
- The mechanism of action: Presumably inhibits enzymes that destroy cartilage, stimulates the synthesis of proteoglycans and hyaluronic acid, has an anti -inflammatory effect.
- Forms: Chondroitin Sulfate.
- Dosage: Usually 800-1200 mg per day.
- Side effects: Rarely – dyspepsia, nausea, diarrhea.
- Contraindications: Individual intolerance, pregnancy, lactation.
- Clinical research: The results are contradictory. Some studies show a moderate decrease in pain and improving the function of joints with osteoarthritis, others do not reveal a significant effect. Efficiency may depend on the quality of chondroitin and the stage of the disease.
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Methyl sulfonylmetatan (MSM):
- Description: Organic compound of sulfur.
- The mechanism of action: Presumably has an anti -inflammatory and antioxidant effect, is involved in the synthesis of collagen.
- Dosage: Usually 1500-3000 mg per day.
- Side effects: Rarely – dyspepsia, nausea, diarrhea, headache.
- Contraindications: Individual intolerance, pregnancy, lactation.
- Clinical research: Some studies show a decrease in pain and improving joint function for osteoarthritis, especially in combination with glucosamine and chondroitin.
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Hyaluronic acid:
- Description: Glycosaminoglican, the main component of the synovial fluid.
- The mechanism of action: It improves the viscosity of synovial fluid, lubricates the joint, reduces friction, has an anti -inflammatory effect.
- Forms: It is taken inside (in the form of capsules or solution) or introduced directly into the joint (in the form of injections).
- Dosage: Depends on the form of release.
- Side effects: When taking orally – rarely dyspepsia. With injections – pain, swelling at the injection site.
- Contraindications: Individual intolerance, pregnancy, lactation, infection in the joint.
- Clinical research: Injections of hyaluronic acid show the effectiveness in decreasing pain and improving the function of joints with osteoarthritis, especially the knee joint. Supporting is less effective, but some studies show an improvement in cartilage hydration.
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Collagen (hydrolyzed):
- Description: The main protein of connective tissue, including cartilage.
- The mechanism of action: Presumably contributes to the restoration of cartilage, stimulates the synthesis of collagen.
- Types of collagen: Type I collagen (contained in the skin, bones, ligaments), type II collagen (contained in cartilage). For joints, type II collagen is usually used.
- Dosage: Usually 5-10 g per day.
- Side effects: Rarely – dyspepsia.
- Contraindications: Individual intolerance, pregnancy, lactation.
- Clinical research: Some studies show a decrease in pain and improving the function of joints for osteoarthritis, especially when using a non -aatured collagen type II.
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Omega-3 fatty acids:
- Description: Polyunsaturated fatty acids contained in fish oil.
- The mechanism of action: They have an anti -inflammatory effect, reduce the level of inflammatory mediators.
- Dosage: Usually 1-3 g per day (EPA and DHA).
- Side effects: Fish taste, dyspepsia, blood thinning.
- Contraindications: Individual intolerance, blood coagulation, taking anticoagulants.
- Clinical research: Some studies show a decrease in pain and improving the function of joints with osteoarthritis and rheumatoid arthritis.
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Vitamin D:
- Description: Fatable vitamin, necessary for the health of bones and joints.
- The mechanism of action: Participates in the regulation of the metabolism of calcium and phosphorus, necessary for the formation of bone tissue, has an immunomodulating effect.
- Dosage: Depends on the level of vitamin D in the blood. Usually 1000-2000 IU per day.
- Side effects: With an overdose – nausea, vomiting, weakness, hypercalcemia.
- Contraindications: Hypercalcemia, hypervitaminosis D.
- Clinical research: Vitamin D deficiency is associated with an increased risk of development of osteoarthritis and rheumatoid arthritis. Taking vitamin D can improve the condition of bones and joints, especially in people with deficiency.
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Kurkumin (turmeric extract):
- Description: The active substance contained in the turmeric.
- The mechanism of action: It has an anti -inflammatory and antioxidant effect, inhibits enzymes involved in inflammation.
- Dosage: Usually 500-1000 mg per day.
- Side effects: Rarely – dyspepsia, diarrhea.
- Contraindications: Individual intolerance, gallstone disease, taking anticoagulants.
- Clinical research: Some studies show a decrease in pain and improving the function of joints with osteoarthritis. The bioavailability of curcumin is low, so it is recommended to use drugs with improved bioavailability (for example, with piperin).
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Boswelia (Boswellia Serrata):
- Description: The plant used in Ayurvedic medicine.
- The mechanism of action: It has an anti-inflammatory effect, inhibits the 5-lipoxygenase enzyme, which is involved in the synthesis of leukotrienes (inflammatory mediators).
- Dosage: Usually 300-400 mg per day.
- Side effects: Rarely – dyspepsia, nausea.
- Contraindications: Individual intolerance, pregnancy, lactation.
- Clinical research: Some studies show a decrease in pain and improving the function of joints with osteoarthritis.
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Avocado and soybean beans (Avocado-Sobean Unsaponifia Bybles-Asu):
- Description: Avocado extract and soybeans.
- The mechanism of action: Presumably inhibits enzymes that destroy cartilage, stimulates the synthesis of collagen and proteoglycans, has an anti -inflammatory effect.
- Dosage: Usually 300 mg per day.
- Side effects: Rarely – dyspepsia.
- Contraindications: Individual intolerance, pregnancy, lactation.
- Clinical research: Some studies show a decrease in pain and improving the function of joints with osteoarthritis.
IV. Reviews of doctors about the dietary supplement for joints
Doctors often take a cautious position in relation to the dietary supplements for the joints. These are the main points that they emphasize:
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Not enough evidence base: Most doctors admit that clinical studies of dietary supplements for joints often have a limited scale, conflicting results and do not correspond to strict criteria for evidence -based medicine. Many studies are financed by dietary supplements, which can affect the results.
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Individual effectiveness: Even if individual studies show a positive effect, doctors emphasize that the reaction to dietary supplements can vary from a person to a person. What helps one patient can be completely ineffective for another.
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Not replacing the main treatment: Doctors insist that dietary supplements should not be considered as a replacement for the traditional treatment of joint diseases (painkillers, anti -inflammatory drugs, physiotherapy, physiotherapy exercises, surgical intervention). Bades can only be used as an addition to the main treatment and only after consulting a doctor.
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Quality and safety control: Doctors are concerned that quality control of dietary supplements is often insufficient. The composition indicated on the label may not correspond to the real content. There is also a risk of contamination of dietary supplements by harmful substances. It is important to choose dietary supplements from well -known manufacturers with a good reputation.
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Possible side effects and interactions with drugs: Doctors warn about the possible side effects of dietary supplements and their interaction with other drugs that the patient takes. For example, omega-3 fatty acids can dilute blood and enhance the effect of anticoagulants. Kurkumin can interact with some drugs metabolized by the liver.
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Placebo effect: Doctors admit that a placebo effect can play an important role in positive reviews about dietary supplements. Faith in the effectiveness of the drug can in itself lead to an improvement in condition.
Specific comments of doctors on separate dietary supplements:
- Glucosamine and chondroitin: Some doctors believe that glucosamine and chondroitin can be useful in the early stages of osteoarthritis, but their effectiveness decreases as the disease progresses. They emphasize that it is important to use high -quality drugs and observe the recommended dosage.
- Hyaluronic acid: Injections of hyaluronic acid, according to many doctors, are an effective method of treating osteoarthrosis of the knee joint, but they require qualified execution and may have side effects. The intake of hyaluronic acid inward is considered less effective.
- Collagen: Some doctors recommend collagen to maintain joint health, especially collagen type II. They note that it is important to choose a hydrolyzed collagen for better absorption.
- Omega-3 fatty acids: Doctors often recommend omega-3 fatty acids to reduce inflammation in the joints, especially with rheumatoid arthritis.
- Vitamin D: Doctors emphasize the importance of maintaining the normal level of vitamin D in the blood for the health of bones and joints. They recommend taking an analysis for vitamin D and take additives in case of deficiency.
- Curcumin and Boswelia: Some doctors consider Kurkumin and Bosvelia as potentially useful means to reduce inflammation in the joints, but emphasize the need for further research.
General conclusion of doctors: Bad for joints can be useful in some cases, but they should not be considered as the main treatment. It is important to consult a doctor before taking dietary supplements in order to evaluate the risks and advantages, choose the right drug and dosage, as well as exclude possible interactions with drugs.
V. Customer reviews about the dietary supplement for joints
Customer reviews about the dietary supplement for joints are extremely diverse and often contradictory. Many positive reviews can be associated with a placebo effect. It is important to consider that the reviews are subjective and are not a replacement for consultation with a doctor.
General trends in the reviews:
- Positive reviews: Many buyers note a decrease in pain, improvement of mobility, reduction of stiffness in the joints after taking dietary supplements. Some note that dietary supplements help them return to an active lifestyle.
- Negative reviews: Many buyers do not see any effect from receiving dietary supplements. Some note side effects, such as dyspepsia, nausea, diarrhea. Some complain about the high cost of dietary supplements.
- The effect depends on the stage of the disease: Many buyers note that dietary supplements are more effective in the early stages of the disease, when the cartilage is not yet very destroyed.
- Combined technique: Many buyers note that a combined technique of several dietary supplements (for example, glucosamine, chondroitin, MSM) is more effective than taking one dietary supplement.
- The importance of regular reception: Many buyers note that in order to achieve the effect, it is necessary to take dietary supplements regularly and for a long time (at least 3 months).
- Different manufacturers are a different effect: Many buyers note that the effectiveness of dietary supplements may depend on the manufacturer and the quality of raw materials.
- Skeptical reviews: Some buyers believe that dietary supplements are a waste of money and that they do not have any real effect.
Examples of reviews on individual dietary supplements (fictional, but reflecting general trends):
- Glucosamine and chondroitin:
- “I have been taking glucosamine and chondroitin for 3 months. The pain in the knee has become less, I can walk longer without pain.”
- “I drank a course of glucosamine and chondroitin, but I did not feel any effect. Money is right.”
- “Glucosamine and chondroitin helped me reduce stiffness in the joints in the morning. But the effect is not immediately, I need to drink for a long time.”
- Hyaluronic acid:
- “I injured hyaluronic acid in the knee. The pain passed for several months, then I had to repeat.”
- “I took hyaluronic acid in capsules, but did not notice the effect.”
- Collagen:
- “I drink collagen for joints and for my skin. I noticed that the joints began to hurt less and the skin – more elastic.”
- “Collagen did not help me get rid of joint pain.”
- MSM:
- “MSM relieves inflammation and joint pain.”
- “MSM caused me a disorder of the stomach.”
- Omega-3:
- “Omega-3 helps me reduce inflammation in the joints with rheumatoid arthritis.”
- “From Omega-3 I have a fish taste in my mouth.”
- Curcumin:
- “Kurkumin relieves joint pain well, but it must be taken with piperin for better absorption.”
- “Kurkumin had no effect on me.”
Important points that should be considered when reading reviews:
- Individuality: The reaction to dietary supplements can vary from person to person.
- Stage of the disease: Bades can be more effective in the early stages of the disease.
- The reliability of reviews: Not all reviews are reliable. Some reviews can be registered.
- Complex approach: Bades should be used in combination with other treatment methods (physiotherapy exercises, diet, medicine).
General conclusion of customers: Customer reviews about dietary supplements for joints are contradictory. Some buyers note a positive effect, others do not see any effect. It is important to consider individual characteristics, stage of the disease, the reliability of reviews and use dietary supplements in combination with other treatment methods.
VI. Criteria for choosing dietary supplements for joints
The choice of dietary supplements for joints is a difficult task that requires a balanced approach. The following criteria will help make the right choice:
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Consultation with a doctor: The most important step is a consultation with a doctor. The doctor will be able to evaluate your condition, determine the cause of pain in the joints, exclude serious diseases and give recommendations for the choice of dietary supplements. The doctor will also be able to evaluate possible risks and advantages of bades, as well as exclude possible interactions with other drugs.
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Composition and dosage: Carefully study the composition of the dietary supplement. Make sure that it contains components whose efficiency is confirmed by clinical studies (glucosamine, chondroitin, MSM, hyaluronic acid, collagen, omega-3, vitamin D, curcumin, bosvelia, ASU). Pay attention to the dosage of the components. The dosage must correspond to the recommended.
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Output form: Bad for joints are available in various forms: capsules, tablets, powders, solutions, gels, creams. The choice of release form depends on your preferences and convenience of application. Capsules and tablets are conveniently taken inside. Gels and creams can be applied directly to the joint area. Injections of hyaluronic acid should only be performed by a doctor.
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Manufacturer: Choose dietary supplements from famous manufacturers with a good reputation. Find out how long the company works in the market, what reviews it has, whether it has quality certificates. Avoid buying dietary supplements from unknown manufacturers, especially on the Internet.
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Certification: Pay attention to the availability of quality certificates (for example, GMP – Good Manufacturing Practice). Certification ensures that the dietary supplement is made in accordance with quality and safety standards.
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Reviews: Read reviews about the diet. Pay attention to positive and negative reviews, what side effects buyers note. Keep in mind that the reviews are subjective and are not a replacement for a consultation with a doctor.
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Price: The price of dietary supplements is not always an indicator of its quality. Do not buy the most expensive dietary supplement in the hope that it will be the most effective. Compare the prices of dietary supplements from different manufacturers and select the best option for the price-quality ratio.
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Compatibility with other drugs: If you take any medication, be sure to consult a doctor to make sure that the dietary supplement is compatible with these drugs. Some dietary supplements can interact with medicines and enhance or weaken their effect.
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Contraindications: Carefully study the contraindications for the use of dietary supplements. If you have any diseases, be sure to consult a doctor to make sure that dietary supplements are not contraindicated to you.
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Best before date: Pay attention to the shelf life of the dietary supplement. Do not use dietary supplements with an expired shelf life.
An example of a bad selection (hypothetical):
Suppose you have an osteoarthrosis of the knee joint, and you want to try a dietary supplement based on glucosamine and chondroitin.
- Consultation with a doctor: You consult a doctor who confirms the diagnosis of osteoarthritis and recommends you to try dietary supplements based on glucosamine and chondroitin as an addition to the main treatment (physiotherapy physical education).
- Composition and dosage: You choose a dietary supplement containing glucosamine sulfate (1500 mg) and chondroitin sulfate (1200 mg) in a daily dose.
- Output form: You prefer capsules, as it is convenient to take them.
- Manufacturer: You choose a dietary supplement from a well -known manufacturer having a good reputation and quality certificates.
- Reviews: You read reviews about the dietary supplement and make sure that most buyers note a positive effect.
- Price: You compare the prices of dietary supplements from different manufacturers and choose the best option for the price-quality ratio.
- Compatibility with other drugs: You tell the doctor that you are taking other medicines, and the doctor confirms that the dietary supplement is compatible with these drugs.
- Contraindications: You study contraindications for the use of dietary supplements and are convinced that you have no contraindications.
- Best before date: You check the expiration date of the dietary supplement.
Following these criteria, you can make a conscious choice of dietary supplement for joints, which is more likely to have a positive effect and will not harm your health. Remember that dietary supplements are not a panacea, and they should be used in combination with other treatment methods and under the supervision of a doctor.
VII. Alternative methods of treating joint diseases
In addition to dietary supplements, there are many other methods of treating joint diseases that can be more effective or used in combination with dietary supplements. It is important to consider all possible treatment options and choose the most suitable approach with the doctor.
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Medication:
- Anesthetic drugs: Paracetamol, non -steroidal anti -inflammatory drugs (NSAIDs) – ibuprofen, diclofenac, ketoprofen, nimesulide. NSAIDs can cause side effects from the gastrointestinal tract, so they should be taken with caution and under the control of a doctor.
- Corticosteroids: Prednisolone, methylprednizolon. Used to reduce inflammation for rheumatoid arthritis and other inflammatory joint diseases. Corticosteroids have serious side effects, so they should be taken only as prescribed by a doctor and under his control.
- Disease drugs (DMARDS): Metotrexate, sulfasalazine, leflunomide. Used to treat rheumatoid arthritis and other autoimmune joint diseases. Dmards suppress the immune system and can cause side effects.
- Biological drugs: FNO inhibitors, IL-6 inhibitors, inhibitors of co-stimulation of T-lymphocytes. They are used to treat rheumatoid arthritis and other autoimmune joint diseases when DMARDS is ineffective. Biological drugs are expensive and can increase the risk of infections.
- Drugs that reduce uric acid levels: Allopurinol, Phoebeksostat. Used to treat gout.
- Hyaluronic acid injections: They are introduced directly into the joint to improve the viscosity of the synovial fluid and reduce friction.
- Injections of corticosteroids: Introduced directly into the joint to reduce inflammation and pain.
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Physiotherapy:
- Exercise: Therapeutic physical education (exercise therapy) helps strengthen the muscles surrounding the joint, improve mobility and reduce pain. It is important to perform exercises correctly and under the control of a physiotherapist.
- Massage: Massage helps to improve blood circulation, reduce muscle tension and pain.
- Thermal procedures: Thermal procedures (heating pads, compresses, paraffin baths) help reduce pain and stiffness.
- Cold procedures: Cold procedures (ice compresses) help reduce inflammation and pain.
- Electrotherapy: Electrotherapy (electrophoresis, ultrasound, laser therapy) can help reduce pain and inflammation.
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Orthopedic devices:
- Orthes: Orthes (knee pads, bandages) help stabilize the joint, reduce the load and pain.
- Carrows and crutches: Cables and crutches help redistribute the load and reduce pain when walking.
- Insoles: Insoles help to correctly distribute the load on the foot and reduce the pain in the knees and hip joints.
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Surgical treatment:
- Arthroscopy: The minimum invasive surgical procedure that allows you to examine the joint from the inside and perform the necessary manipulations (removal of damaged cartilage, meniscus, bone growths).
- Endoprosthetics: Replacement occasion