TOP dietary supplements for arthrosis

Top dietary supplement for joints with arthrosis: detailed analysis and recommendations

Arthrosis, a degenerative disease of the joints, affects millions of people around the world, leading to pain, stiffness and limiting mobility. Although pharmaceuticals play an important role in the treatment of arthrosis, many patients turn to biologically active additives (dietary supplements) as a potential way to alleviate symptoms, improve joint function and slowing down the progression of the disease. It is important to emphasize that dietary supplements are not medicines and should not replace consultation with a doctor or treatment prescribed by him. However, with the right approach and under the control of a specialist, some dietary supplements can be a useful addition to the complex therapy of arthrosis. In this article, we will consider the most promising and studied dietary supplements for arthrosis, we will analyze in detail their mechanisms of action, efficiency, dosage, possible side effects and interaction with other drugs.

1. Glucosamine and chondroitin:

Glucosamine and chondroitin are perhaps the most famous and widely used dietary supplements for joints. They are natural components of cartilage and play an important role in maintaining its structure and function.

• The mechanism of action: Glucosamine is the precursor of glycosaminoglycans, key components of cartilage matrix. It is believed that it stimulates the synthesis of glycosaminoglycans and hyaluronic acid, contributing to the restoration of cartilage and improving its amortizing properties. Chondroitin sulfate, in turn, inhibits enzymes that destroy cartilage fabric (for example, metal propriets) and helps to keep water in cartilage, ensuring its elasticity and stress resistance.

• Efficiency: Scientific data on the effectiveness of glucosamine and chondroitin with arthrosis are contradictory. Some studies show a significant decrease in pain and improving the joint function, especially with prolonged use, while others do not detect a significant difference between dietary supplements and placebo. It is important to note that research results can vary depending on the type of glucosamine (sulfate or hydrochloride), a source of chondroitin, dosage, duration of treatment and the severity of arthrosis.

• Dosage: The recommended dose of glucosamine is usually 1,500 mg per day, divided into several tricks. Chondroitin is usually taken at a dose of 800-1200 mg per day. The effect usually does not appear immediately, but after a few weeks or months of regular administration.

• Side effects: Glucosamine and chondroitin are usually well tolerated, but in some cases light side effects can cause, such as nausea, diarrhea, heartburn and constipation. Allergic reactions are rare.

• Interactions with drugs: Glucosamine can enhance the effect of anticoagulants (for example, warfarin), increasing the risk of bleeding. Therefore, patients taking anticoagulants should consult a doctor before taking glucosamine.

• Output forms: Glucosamine and chondroitin are available in various forms, including tablets, capsules and powders. Often they are produced in combination with each other, as well as with other components, such as MSM and hyaluronic acid.

2. Methyl sulfonylmetatan (MSM):

MSM is an organic compound of sulfur, which is found in nature in plants, animals and man. Sure plays an important role in the formation of collagen, which is necessary for the health of cartilage, bones and connective tissue.

• The mechanism of action: It is believed that MSM has anti -inflammatory and antioxidant properties, and also contributes to the formation of collagen and strengthen connective tissue. It can reduce pain and improve joint mobility.

• Efficiency: Some studies show that MSM can be effective in reducing pain and inflammation with arthrosis, especially in combination with glucosamine and chondroitin. However, additional studies are needed to confirm its effectiveness and determine the optimal dosage.

• Dosage: The recommended dose of MSM is usually 1500-3000 mg per day, divided into several receptions.

• Side effects: MSM is usually well tolerated, but in some cases can cause light side effects, such as nausea, diarrhea and headache.

• Interactions with drugs: Currently, it is not known about the significant interactions of MSM with other drugs.

3. Hyaluronic acid:

Hyaluronic acid is a natural component of the synovial fluid that lubricates the joints and provides their smooth sliding. With arthrosis, the concentration of hyaluronic acid in the synovial fluid decreases, which leads to an increase in friction and joint pain.

• The mechanism of action: Hyaluronic acid has a high ability to hold water, which provides its lubricating and shock -absorbing properties. When administered orally, hyaluronic acid can stimulate the synthesis of its own hyaluronic acid in the joints and reduce inflammation.

• Efficiency: Studies show that hyaluronic acid injections in the joint can be effective in reducing pain and improving the function of joints with arthrosis of the knee joint. However, the effectiveness of the oral administration of hyaluronic acid has been less studied. Some studies show that it can be effective in reducing pain and improving the joint function, while others do not find a significant difference between dietary supplements and placebo.

• Dosage: The recommended dose of hyaluronic acid for oral administration is usually 80-200 mg per day.

• Side effects: Hyaluronic acid is usually well tolerated, but in rare cases, allergic reactions can cause.

• Interactions with drugs: Currently, it is not known about significant interactions of hyaluronic acid with other drugs.

4. Curcumin:

Kurkumin is an active ingredient in turmeric, plants known for its anti -inflammatory and antioxidant properties.

• The mechanism of action: Kurkumin inhibits various inflammatory molecules and enzymes, such as cyclooxygenase-2 (COX-2) and lipoxygenase (log), which are involved in the development of inflammation and pain in arthrosis. It also has antioxidant properties, protecting the joints of the joints from damage by free radicals.

• Efficiency: Many studies show that curcumin can be effective in reducing pain and inflammation with arthrosis, comparable to the effect of non -steroidal anti -inflammatory drugs (NSAIDs). However, the bioavailability of curcumin during oral administration is low, so it is important to choose products containing bio -access forms of curcumin, such as kurkumin with pyperin (black pepper) or liposomal curcumin.

• Dosage: The recommended dose of curcumin varies depending on the form of release and concentration of the active substance. It is usually recommended to take 500-2000 mg of curcumin per day, divided into several tricks.

• Side effects: Kurkumin is usually well tolerated, but in some cases can cause light side effects, such as nausea, diarrhea and discomfort in the abdomen.

• Interactions with drugs: Kurkumin can enhance the effect of anticoagulants and anti -agents, increasing the risk of bleeding. Therefore, patients taking these drugs should consult a doctor before taking curcumin.

5. Omega-3 fatty acids:

Omega-3 fatty acids, such as eicopascentenoic acid (EPK) and daily oxaenoic acid (DGC), are contained in fish, linen seeds and other products. They have anti -inflammatory properties and can be useful for arthrosis.

• The mechanism of action: Omega-3 fatty acids inhibit the synthesis of inflammatory prostaglandins and leukotrienes, reducing inflammation and joint pain.

• Efficiency: Some studies show that omega-3 fatty acids can be effective in reducing the pain and stiffness of joints with arthrosis, as well as in improving the function of the joints.

• Dosage: The recommended dose of omega-3 fatty acids is usually 1000-3000 mg per day containing EPC and DGK.

• Side effects: Omega-3 fatty acids are usually well tolerated, but in some cases light side effects can cause, such as fish belching, nausea and diarrhea.

• Interactions with drugs: Omega-3 fatty acids can enhance the effects of anticoagulants and antiplatelet agents, increasing the risk of bleeding. Therefore, patients taking these drugs should consult a doctor before taking omega-3 fatty acids.

6. Boswellia Serrata Extract):

Boswellia is a plant growing in India and Africa. Boswellia extract contains bosvelic acids that have anti -inflammatory properties.

• The mechanism of action: Bosvevel acids inhibit the 5-lipoxygenase enzyme (5 -l), which is involved in the synthesis of leukotrienes, inflammatory molecules playing the role in the development of arthrosis.

• Efficiency: Some studies show that Boswellial extract can be effective in reducing pain and improving joint function with arthrosis.

• Dosage: The recommended dose of bosvellia extract is usually 300-500 mg per day containing 60-65% of bosvelic acids.

• Side effects: Boswellial extract is usually well tolerated, but in some cases can cause light side effects, such as nausea, diarrhea and heartburn.

• Interactions with drugs: Currently, it is not known about the significant interactions of Boswellial extract with other drugs.

7. Avocado-“non-combusable compounds (ASU):

ASU is an extract obtained from avocados and soy. It contains phytosterols, vitamins and other beneficial substances.

• The mechanism of action: ASU has anti -inflammatory and chondroprotective properties. It can stimulate the synthesis of collagen and other components of cartilage, as well as inhibit enzymes that destroy cartilage.

• Efficiency: Some studies show that ASU can be effective in reducing pain and improving joint function with arthrosis, especially with arthrosis of the knee joint.

• Dosage: The recommended ASU dose is usually 300 mg per day.

• Side effects: ASU is usually well tolerated, but in rare cases can cause light side effects, such as nausea and discomfort in the abdomen.

• Interactions with drugs: Currently, it is not known about significant ASU interactions with other drugs.

8. Collagen (Type II):

Collagen is the main structural protein of cartilage. Type II collagen is especially important for maintaining joint health.

• The mechanism of action: Type II collagen can stimulate the synthesis of its own collagen in the joints and reduce inflammation. Type II undlanaturated collagen, in particular, can work through a process called oral tolerance, helping to modulate an immune response and reduce an autoimmune attack on the articular cartilage.

• Efficiency: Some studies show that the intake of type II collagen can be effective in reducing pain and improving joint function with arthrosis.

• Dosage: The recommended dose of type II collagen varies depending on the type of product. Type ilgen -bungered collagen is usually taken at a dose of 40 mg per day. Type hydrolyzed collagen is usually taken in large doses, for example, 10 g per day.

• Side effects: Collagen is usually well tolerated, but in rare cases it can cause allergic reactions.

• Interactions with drugs: Currently, it is not known about the significant interactions of collagen with other drugs.

9. Vitamin D:

Vitamin D plays an important role in the health of bones and joints. Vitamin D deficiency can increase the risk of arthrosis and worsen its symptoms.

• The mechanism of action: Vitamin D helps to absorb the calcium necessary to maintain bone health. It also has anti -inflammatory properties and can affect the function of the immune system.

• Efficiency: Some studies show that maintaining an adequate level of vitamin D can reduce the risk of arthrosis and reduce its symptoms.

• Dosage: The recommended dose of vitamin D varies depending on the level of vitamin D in the blood and individual needs. It is usually recommended to take 600-2000 IU vitamin D per day.

• Side effects: When taking vitamin D in high doses, side effects can occur, such as nausea, vomiting and hypercalcemia.

• Interactions with drugs: Vitamin D can interact with some drugs such as thiazide diuretics and cardiac glycosides.

10. Same (s-adenosylmetionine):

Same is a natural compound that is found in the human body. It participates in many biochemical reactions, including the synthesis of cartilage and neurotransmitters.

• The mechanism of action: Same has anti -inflammatory and analgesic properties. It can stimulate the synthesis of proteoglycans, the main components of cartilage, and reduce joint pain.

• Efficiency: Some studies show that SAME can be effective in reducing pain and improving the joint function with arthrosis, comparable to the effect of NSAIDs.

• Dosage: The recommended dose of SAME is usually 600-1200 mg per day, divided into several doses.

• Side effects: Same can cause side effects, such as nausea, diarrhea and insomnia.

• Interactions with drugs: Same can enhance the effect of antidepressants, which can lead to the development of serotonin syndrome. Therefore, patients taking antidepressants should consult a doctor before taking SAME.

Important comments when choosing and using dietary supplements for joints for arthrosis:

• Consultation with a doctor: Before taking any dietary supplement, it is necessary to consult a doctor in order to make sure of his safety and the absence of contraindications. The doctor can also help determine the most suitable dietary supplement and dosage depending on individual needs and health status.

• Quality product: It is important to choose dietary supplements from reliable manufacturers that guarantee the quality and cleanliness of their products. Pay attention to the availability of quality certificates and independent laboratory research.

• Dosage and duration of the reception: Follow the instructions for use and do not exceed the recommended dosage. The effect of taking dietary supplements usually does not appear immediately, but after a few weeks or months of regular reception.

• Individual tolerance: Carefully follow your reaction to dietary supplements. When any side effects appear, it is necessary to stop taking and consult a doctor.

• Complex approach: Bades are not panacea and cannot replace the main treatment of arthrosis, such as physiotherapy, physiotherapy exercises and drug therapy. They should be considered as an addition to an integrated approach to the treatment of arthrosis.

• Evaluation of effectiveness: Evaluate the effectiveness of dietary supplements after a few months of regular reception. If you have not noticed improvement, consult a doctor about further treatment tactics.

• Interaction with other drugs: Inform your doctor about all the dietary supplements that you accept to avoid possible interactions with other drugs.

• Information: Carefully study the information about the dietary supplement, which you plan to accept, including its composition, mechanism of action, effectiveness, side effects and interaction with other drugs.

The choice of dietary supplement for joints with arthrosis is an individual process that requires consulting a doctor, a thorough study of information and an attentive attitude to your health. Remember that dietary supplements can be a useful addition to a comprehensive treatment of arthrosis, but they should not replace the main treatment and are not a panacea. The correct approach and compliance with the doctor’s recommendations will help you achieve the best results in the fight against this disease.