Testosterone dietary supplements: improving sperm quality.
Section 1: testosterone, sperm and fertility – interconnection.
Testosterone, the main male sex hormone, plays a key role in various aspects of male health, including libido, muscle mass, bone density and, most importantly, fertility. The level of testosterone is closely related to the production of sperm, its quality and mobility of sperm. The low level of testosterone (hypogonadism) is often associated with problems with fertility, including a decrease in sperm concentration (oligospermia), asthenozoospermia (decrease in sperm mobility) and teratozoosperm (abnormal morphology of spermatozoa).
1.1 The role of testosterone in spermatogenesis.
Spermatogenesis, the process of forming sperm, occurs in the seed tubules. This complex process is under the control of several hormones, including luteinizing hormone (LH), follicle -stimulating hormone (FSH) and testosterone. LH stimulates Lydig’s cells in testicles to produce testosterone. Testosterone, in turn, is critical to maintain spermatogenesis. It contributes to the proliferation and differentiation of cell cells that support and nourish developing spermatozoa. Moreover, testosterone is necessary for the final stages of sperm maturation, ensuring their mobility and the ability to fertilize the egg.
1.2 The consequences of a low level of testosterone for sperm quality.
When the level of testosterone decreases, spermatogenesis is disturbed. This can lead to the following consequences:
- Reducing the concentration of sperm (oligospermia): An insufficient number of sperm in the ejaculate significantly reduces the likelihood of natural conception.
- Reduced mobility of sperm (asthenozoospermia): Spermatozoa are not able to move efficiently to the egg, which complicates fertilization.
- Anomalous morphology of sperm (teratozoospermia): Spermatozoa have structural defects that prevent their ability to penetrate into the egg.
- Reducing the volume of ejaculate: The total ejaculate can decrease, which can also affect fertility.
- Increased damage to sperm DNA: DNA of sperm can be damaged, which can lead to problems with the development of the embryo and increasing the risk of miscarriage.
1.3 Factors affecting testosterone levels and sperm quality.
Many factors can affect the level of testosterone and, therefore, the quality of sperm. These include:
- Age: The level of testosterone naturally decreases with age.
- Obesity: Excess weight and obesity are associated with a decrease in testosterone levels. The adipose tissue contains an enzyme aromatase that turns testosterone into estrogen (female sex hormone).
- Chronic diseases: Diabetes, cardiovascular diseases and other chronic conditions can negatively affect testosterone levels.
- Taking certain drugs: Some drugs, such as anabolic steroids, opioid painkillers and antidepressants, can reduce testosterone levels.
- The effects of toxins: The impact of certain toxins, such as pesticides, heavy metals and bisphenol A (BPA), can disrupt the hormonal balance and reduce testosterone levels.
- Stress: Chronic stress can suppress testosterone production.
- Inal meals: The deficiency of certain nutrients, such as zinc, selenium and vitamin D, can negatively affect the level of testosterone and sperm quality.
- Smoking and drinking alcohol: Smoking and excessive alcohol consumption are associated with a decrease in testosterone levels and a deterioration in sperm quality.
- Varicocele: The expansion of the veins of the seed cord (varicocele) can increase the temperature in the testicles and disrupt spermatogenesis.
Section 2: Bades to increase testosterone and improve sperm quality – a review.
Biologically active additives (dietary supplements) are widely used to increase testosterone levels and improve sperm quality. It is important to understand that the efficiency and safety of dietary supplements can vary, and care must be taken when using them. Before taking any dietary supplements, it is recommended to consult a doctor in order to exclude contraindications and interaction with other drugs.
2.1 additives confirmed by scientific research (with a moderate evidence level):
Some additives have stronger scientific support than others, with regard to their ability to increase testosterone levels and improve sperm quality. It is important to note that even for these additives, evidence is often limited by small studies and require further confirmation.
- D-paraginic acid (D-AA): D-AA is an amino acid that is involved in the regulation of testosterone production. Some studies have shown that D-AA can increase testosterone levels and improve sperm quality, especially in men with low testosterone levels. However, other studies did not show a significant effect. The dosage is usually 2-3 grams per day.
- Tribulus Terrestris Tribulus: Tribulus is a plant that is traditionally used in Ayurvedic medicine to increase libido and improve male sexual function. Although the tribulus is often advertised as a testosterone booster, the scientific data confirming this is limited. Some studies have shown that tribulus can improve sexual function and sperm quality, but does not necessarily increase testosterone levels. The dosage varies, but usually is 750-1500 mg per day. It is important to note that some studies have shown the lack of effect.
- Pajuk (Fenugreek): A fencth is a plant that is used as a seasoning and a drug. Some studies have shown that the fencing can increase testosterone levels, improve libido and sexual function. However, additional studies are needed to confirm these results. The dosage is usually 500-600 mg per day.
- Zinc: Zinc is an important trace element that plays a key role in the production of testosterone and sperm. Zinc deficiency can lead to a decrease in testosterone levels and a deterioration in sperm quality. Taking zinc as an additive can improve the level of testosterone and sperm quality in men with zinc deficiency. The dosage is usually 15-30 mg per day.
- Vitamin D: Vitamin D is important for many aspects of health, including reproductive function. Vitamin D deficiency is associated with a decrease in testosterone levels and a worsening of sperm quality. Taking vitamin D as an additive can improve the level of testosterone and sperm quality in men with vitamin D deficiency. The dosage varies depending on the level of vitamin D in the blood, but usually is 200-5000 IU per day.
- Coenzyme Q10 (CoQ10): COQ10 is an antioxidant that plays an important role in energy metabolism. Some studies have shown that COQ10 can improve the mobility and concentration of sperm. The dosage is usually 100-300 mg per day.
- L-Carnitin: L-carnitine is an amino acid that plays an important role in the energy metabolism of cells and the transport of fatty acids. Some studies have shown that L-carnitine can improve the mobility and concentration of sperm. The dosage is usually 1-3 grams per day.
- Selenium: Selenium is a trace element that is an important antioxidant. It is necessary for the normal functioning of the thyroid gland and reproductive function. Some studies have shown that selenium can improve sperm mobility. The dosage is usually 55-200 mcg per day.
2.2 additives with less unambiguous evidence (additional studies are required):
Some additives are advertised as testosterone booster and means to improve sperm quality, but scientific data confirming their effectiveness are limited or contradictory.
- Long -leaved eurecoma (Eurycoma Longifolia / Tongkat Ali): The eurecoma of long-leaved is a plant that is traditionally used in Southeast Asia to increase libido and improve male sexual function. Some studies have shown that a long -leaf euricome can increase testosterone levels and improve sperm quality, but other studies did not show a significant effect. Additional studies are needed to confirm these results.
- Maka Peruvian (Maca): Maca is a plant that grows in the Andes. It is used as a food supplement to increase energy, libido and fertility. Some studies have shown that poppy can improve libido and sexual function, but does not necessarily increase testosterone levels. Data on improving sperm quality is limited.
- INDOL-3-carbinol (i3c): I3c is a compound contained in cruciferous vegetables, such as broccoli and cabbage. It affects the metabolism of estrogen. Theoretically, it can help increase testosterone levels by reducing estrogen levels, but the data is limited.
- Resveratrol: Resveratrol is an antioxidant contained in red wine, grapes and berries. Some studies have shown that resveratrol can improve sperm quality, but additional studies are needed to confirm these results and its effect on testosterone levels.
- Brown: Bor is a trace element that plays a role in the metabolism of calcium and magnesium. Some studies have shown that Bor can increase testosterone levels, but other studies have not shown a significant effect.
2.3 risks and side effects of dietary supplements.
Reception of dietary supplements bears certain risks. It is important to know about possible side effects and interactions with other drugs.
- Quality and safety: Bades are not adjusted as strictly as medicines. This means that the quality and safety of dietary supplements can vary. Some dietary supplements may contain ingredients that are not indicated on the label, or contain pollutants.
- Side effects: Bades can cause side effects, especially when taking high doses or when interacting with other drugs.
- Interaction with drugs: Bades can interact with other drugs, which can strengthen or weaken their effect.
- Allergic reactions: Some people can be allergic to certain ingredients contained in dietary supplements.
- Influence on hormonal balance: Bades that affect the level of testosterone can disrupt the hormonal balance, which can lead to undesirable consequences.
2.4 The importance of consulting a doctor.
Before taking any dietary supplements, especially to increase the level of testosterone and improve sperm quality, you need to consult a doctor. The doctor can assess the state of health, determine the possible causes of low level of testosterone or problems with fertility, exclude contraindications and interaction with other drugs, and also give recommendations on the safe and efficient use of dietary supplements. Self -medication can be dangerous.
Section 3: Other ways to improve sperm quality, in addition to dietary supplements.
In addition to taking dietary supplements, there are other ways to improve the quality of sperm, which include changes in the lifestyle and diet.
3.1 Healthy lifestyle.
- Proper nutrition: A balanced diet rich in fruits, vegetables, whole grain products and low -fat sources of protein is important to health and fertility. Processed foods, sweet drinks and excessive consumption of saturated and trans fats should be avoided.
- Physical activity: Regular physical exercises are good for health and can increase testosterone levels. However, excessive training should be avoided, which can negatively affect hormonal balance.
- Weight loss: Excess weight and obesity are associated with a decrease in testosterone levels and a worsening of sperm quality. Weight reduction can improve the level of testosterone and sperm quality.
- Refusal of smoking and drinking alcohol: Smoking and excessive alcohol consumption are associated with a decrease in testosterone levels and a deterioration in sperm quality. Refusal of smoking and restriction of alcohol consumption can improve sperm quality.
- Stress management: Chronic stress can suppress testosterone production. Stress management techniques, such as yoga, meditation and deep breathing, can help improve hormonal balance.
- Sufficient sleep: A lack of sleep can reduce testosterone levels. It is important to sleep 7-8 hours a day.
- Avoid overheating of the testicles: High temperature in the testicular area can disrupt spermatogenesis. Frequent visits to saunas and jacuzzi, wearing close underwear and laptop on the laptop on the knees for a long time should be avoided.
- Avoid the effects of toxins: The effects of certain toxins, such as pesticides, heavy metals and bisphenol A (BPA), which can disrupt the hormonal balance and reduce testosterone levels should be avoided.
3.2 Diet to improve sperm quality.
Certain nutrients are important to the health of sperm. The inclusion in the diet of products rich in these nutrients can improve sperm quality.
- Antioxidants: Antioxidants, such as vitamin C, vitamin E, selenium and coenzyme Q10, protect sperm from damage to free radicals. Antioxidants are found in fruits, vegetables, nuts and seeds.
- Zinc: Zinc is necessary for the production of testosterone and sperm. Products rich in zinc include meat, poultry, seafood, nuts and seeds.
- Folic acid: Folic acid is important for the normal development of sperm DNA. Folic acid is found in dark green leafy vegetables, legumes and citrus fruits.
- Omega-3 fatty acids: Omega-3 fatty acids are important for the health of sperm. Omega-3 fatty acids are found in fatty fish, such as salmon, tuna and sardines, as well as in linen seeds and walnuts.
- Liquopin: Lycopine is an antioxidant contained in tomatoes and other red fruits and vegetables. Some studies have shown that lycopine can improve sperm mobility.
3.3 medical interventions.
In some cases, medical interventions may be required to improve sperm quality.
- Infection treatment: The infections of the genitourinary system can negatively affect the quality of sperm. Treatment of infections can improve sperm quality.
- Hormonal therapy: In cases of hypogonadism, hormonal therapy can increase testosterone levels and improve sperm quality. However, hormone therapy can have side effects and requires careful medical observation.
- Surgical treatment of varicocele: Surgical treatment of varicocele can improve the quality of sperm in men with varicocele.
- Auxiliary reproductive technologies (ART): If other methods of treatment are ineffective, it is possible to consider auxiliary reproductive technologies, such as extorporepical fertilization (ECO) or intracitoplasmic injection of sperm (ICSI).
Section 4: Scientific research and evidence – a detailed analysis.
The effectiveness of various dietary supplements to increase the level of testosterone and improve sperm quality is supported by varying degrees of scientific evidence. A critical analysis of available studies is necessary for making reasonable decisions. It is important to understand that many studies have restrictions, such as small sample size, lack of control groups or differences in the methodology.
4.1 detailed review of studies on d-asparaginic acid (D-AA).
D-paralgic acid (D-AA) is an amino acid that plays a role in neuroendocrine regulation, including the release of luteinizing hormone (LH) and testosterone.
- Positive results: The study published in the journal “Reproductive Biology and Endocrinology” (2009) showed that taking 3 grams of D-AA per day for 12 days increased the level of testosterone by 42% in men with oligoastenotenotesopermia (low concentration, mobility and morphology of sperm). An improvement in sperm mobility was also observed.
- Conflicting results: Another study published in the journal “Journal of the International Society of Sports Nutrition” (2013) showed that taking 3 grams of D-AA per day for 28 days did not have a significant impact on testosterone levels among trained men. However, an improvement in muscle force was noted.
- Additional considerations: The mechanism of action D-AA involves stimulating the release of LH, which then stimulates the production of testosterone in the testicles. Therefore, D-AA can be more effective in men with hypogonadism caused by insufficient stimulation of LG testicles.
4.2 Analysis of studies on the tribulus Terrestris (Tribulus Terrestris).
Tribulus Terrytris is a plant that is traditionally used in Ayurvedic medicine as an aphrodisiac.
- Ambiguous results: Many studies of the Tertrix tribulus were conducted on animals, and the results are not always applicable to people. Some studies have shown that tribulus can improve libido and sexual function, but does not have a significant effect on testosterone levels. For example, a study published in Journal of Ethnopharmacology (2008) showed that tribulus improves sexual function in men with erectile dysfunction, but does not increase testosterone levels.
- Potential improvement in sperm quality: Some studies suggest that tribulus can improve sperm quality, but additional studies are needed. The mechanism of action can be associated with the antioxidant properties of the tribulus and its ability to protect sperm from damage to free radicals.
- Risks: Tertrix tribulus is generally considered safe, but in rare cases it can cause side effects, such as stomach disorder.
4.3 Assessment of data on fenugree (Fenugreek).
A fencth is a plant that is used as a seasoning and a drug.
- Improving libido and sexual function: Some studies have shown that the fences can improve libido and sexual function in men. The mechanism of action can be associated with an increase in the level of testosterone and other androgens. For example, a study published in the journal Phytotherapy Research (2011) has shown that the fencing extract improves libido and sexual function in men.
- Potential influence on testosterone levels: Some studies suggest that the fencing can increase testosterone levels, but additional studies with larger samples and control groups are needed.
- Risks: The fencing can cause side effects, such as the disorder of the stomach and diarrhea. It can also interact with some drugs such as anticoagulants.
4.4 The role of zinc in fertility and research.
Zinc is an important trace element that plays a key role in many physiological processes, including reproductive function.
- Need for spermatogenesis: Zinc is necessary for normal spermatogenesis and maturation of sperm. He also plays a role in protecting sperm from damage to free radicals.
- Zinc deficiency and fertility: Zinc deficiency is associated with a decrease in testosterone levels and a deterioration in sperm quality. Studies have shown that zinc reception as an additive can improve the level of testosterone and sperm quality in men with zinc deficiency. For example, a study published in the journal Nutrition (2002) showed that zinc intake improves the concentration and mobility of sperm in men with infertility.
- Testosterone Impact: Zinc affects the production of LH and, therefore, on the production of testosterone.
- Risks: Taking high doses of zinc can cause side effects, such as stomach disorder and a decrease in copper levels.
4.5 Vitamin D and its connection with testosterone and sperm are a review of research.
Vitamin D is a fat -soluble vitamin that plays an important role in bone health, immune function and reproductive system.
- Vitamin D receptors in reproductive organs: Vitamin D receptors were found in testicles and other reproductive organs, which indicates its role in reproductive function.
- Vitamin D deficiency and fertility: Vitamin D deficiency is associated with a decrease in testosterone levels and a worsening of sperm quality. Studies have shown that the intake of vitamin D as an additive can improve the level of testosterone and sperm quality in men with vitamin D deficiency. For example, a study published in the journal Human Reproduction (2012) showed that vitamin D improves sperm mobility in men with infertility and vitamin D.
- Risks: Taking high doses of vitamin D can cause hypercalcemia (increased blood calcium levels).
4.6 Coenzyme Q10 (COQ10): antioxidant properties and effect on sperm.
Coenzyme Q10 (CoQ10) is an antioxidant that plays an important role in the energy metabolism of cells.
- Antioxidant Protection: COQ10 protects sperm from damage to free radicals.
- Improving mobility and concentration: Some studies have shown that COQ10 can improve the mobility and concentration of sperm. For example, a study published in the journal Fertility and Sterolyity (2009) showed that the COQ10 reception improves sperm mobility in men with infertility.
- The mechanism of action: COQ10 improves energy metabolism in sperm, which contributes to their mobility.
- Risks: COQ10 is generally considered safe, but in rare cases it can cause side effects, such as stomach disorder.
4.7 L-carnitine: metabolism of fatty acids and the role in sperm mobility.
L-carnitine is an amino acid that plays an important role in the transport of fatty acids in mitochondria, where they are used to produce energy.
- Energy for sperm mobility: L-carnitine provides sperm with the energy necessary for their mobility.
- Improving mobility and concentration: Some studies have shown that L-carnitine can improve the mobility and concentration of sperm. For example, a study published in the journal “Fertility and Stereility” (2004) showed that the intake of L-carnitine improves sperm mobility in men with asthenozoospermia.
- Risks: L-carnitine is generally considered safe, but in rare cases it can cause side effects, such as stomach disorder.
4.8 Selenium: antioxidant activity and support of fertility.
Selenium is a trace element that is an important antioxidant.
- Protection against oxidative stress: Selenium protects sperm from damage to free radicals.
- Support for thyroid function: Selenium is important for the normal function of the thyroid gland, which plays a role in reproductive function.
- Improving mobility: Some studies have shown that selenium can improve sperm mobility.
- Risks: Reception of high doses of selenium can cause selenosis, which is characterized by nausea, vomiting and hair loss.
4.9 Evricoma Long -leaved (Eurycoma Longifolia / Tongkat Ali): Analysis of a limited evidence base.
The eurecoma of long-leaved (Tongkat ali) is a plant that is traditionally used in Southeast Asia to increase libido and improve male sexual function.
- Lack of quality research: The evidence base for the effectiveness of long -leaf euricoma to increase testosterone levels and improve sperm quality is limited. Many studies were conducted on animals or have small samples.
- Potential improvement in libido and sexual function: Some studies suggest that a long -leaf euricome can improve libido and sexual function, but additional studies are needed.
- The mechanism of action: The mechanism of action of long -leaf euricoma is not completely studied, but it is assumed that it can affect the level of testosterone and other androgens.
- Risks: The long -leaved euricome is generally considered safe, but it is necessary to take into account possible interactions with other drugs.
4.10 Maca Peruvian (MACA): improvement of libido, but not always testosterone.
Peruvian poppy is a plant that grows in the Andes. It is used as a food supplement to increase energy, libido and fertility.
- Libido improvement: Studies have shown that poppy can improve libido and sexual function in men.
- A slight effect on testosterone: Most studies have not shown a significant influence of poppies on testosterone levels.
- Potential improvement in sperm quality: Data on improving sperm quality under the influence of poppies is limited and require further research.
- Risks: Poppy is generally considered safe, but it is necessary to take into account possible allergic reactions.
Section 5: Clinical recommendations and protocols.
Currently, there are no single clinical recommendations or protocols for the use of dietary supplements to increase testosterone levels and improve sperm quality. Recommendations should be individual and based on assessing the state of health, the level of hormones and sperm quality.
5.1 Algorithm for decision -making.
- Assessment of health: The doctor must collect an anamnesis, conduct a physical examination and prescribe the necessary tests, including determining the level of testosterone, LH, FSH, prolactin, estradiol and sperm analysis.
- Exclusion of other reasons: The doctor should exclude other causes of a low level of testosterone or problems with fertility, such as hypogonadism, infections, varicocele and genetic disorders.
- Changes in the lifestyle: The doctor should recommend changes in lifestyle, such as proper nutrition, physical activity, weight loss, rejection of smoking and drinking alcohol, stress management and sufficient sleep.
- Consideration of dietary supplements: If changes in lifestyle do not lead to improvement, the doctor may consider using dietary supplements. The choice of dietary supplement should be based on individual needs and preferences of the patient, as well as on scientific evidence and safety.
- Monitoring: The doctor should regularly monitor the level of hormones and sperm quality to evaluate the effectiveness and safety of treatment.
5.2 Recommendations for dosage and duration of admission.
The dosages and duration of the reception of dietary supplements should be determined by the doctor individually. It is important to follow the doctor’s recommendations and not exceed the recommended doses.
5.3 Interaction with other drugs.
It is necessary to take into account the possible interactions of dietary supplements with other drugs that the patient takes. The doctor must analyze the list of drugs in order to exclude undesirable interactions.
5.4 Contraindications.
Dietary supplements have contraindications. It is necessary to take into account the individual contraindications of each dietary supplement.
Section 6: Future research areas.
Additional studies are needed to assess the effectiveness and safety of dietary supplements to increase testosterone levels and improve sperm quality. Future research should be larger, using control groups and standardized protocols. It is also necessary to study the mechanisms of the action of dietary supplements and their impact on various aspects of reproductive function.
6.1 Study of battles’ combinations.
It is necessary to study the effectiveness and safety of battles. The combination of several dietary supplements can be more effective than using one dietary supplement.
6.2 personalized medicine.
Future studies should take into account the individual characteristics of patients, such as genetics, lifestyle and health status. A personalized approach to the choice of dietary supplements can be more effective.
6.3 Development of new dietary supplements.
It is necessary to develop new dietary supplements that would be more effective and safe to increase testosterone levels and improve sperm quality.
6.4 mechanisms for the action of dietary supplements at the molecular level.
It is necessary to study the mechanisms of the action of dietary supplements at the molecular level. This will develop more effective and targeted treatment methods.
Section 7: Final considerations.
The use of dietary supplements to increase testosterone levels and improve sperm quality is a difficult issue. It is important to understand that the efficiency and safety of dietary supplements can vary, and care must be taken when using them. Before taking any dietary supplements, it is recommended to consult a doctor in order to exclude contraindications and interaction with other drugs. Changes in the lifestyle and diet can also play an important role in improving the quality of sperm.