Chapter 1: Understanding of cognitive functions and factors affecting them
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1 Neurobiology of memory and attention:
- Brain structures: Consideration of key areas of the brain involved in the processes of memory and attention, such as hippocampus (the formation of new memories), prefrontal cortex (executive functions, attention, decision -making), amygdala (emotional memory) and cerebellum (motor memory and coordination). A detailed description of the functions of each area and their interaction. Illustrations and diagrams for clarity.
- Neurotransmitter: Description of the role of key neurotransmitters, such as acetylcholine (training, memory, attention), dopamine (motivation, concentration, pleasure), serotonin (mood, sleep, appetite), norepinephrine (vigilance, attention, stress reaction) and GABA (inhibition of neural activity, relaxation). Explanation of the mechanism of action of each neurotransmitter and its effect on cognitive functions.
- Neuroplasticity: An explanation of the concept of neuroplasticity – the ability of the brain to change its structure and functions in response to experience. Discussion of factors contributing to neuroplasticity, such as training, physical exercises, diet and additives. Consideration of neurogenesis (the formation of new neurons) and synaptic plasticity (strengthening or weakening of the connections between neurons).
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2 Factors affecting cognitive functions:
- Age: Discussion of natural age -related changes in the brain, such as a decrease in brain volume, a decrease in the level of neurotransmitters and a slowdown in the speed of information processing. Consideration of diseases associated with age, such as Alzheimer’s disease and Parkinson’s disease. Discussion of strategies for mitigating age -related cognitive functions.
- Stress: Description of the influence of chronic stress on cognitive functions. Explanation of the mechanism of action of cortisol (stress hormone) and its effect on the hippocampus and prefrontal bark. Consideration of stress management techniques, such as meditation, yoga and physical exercises.
- Dream: A detailed description of the importance of sleep for consolidation of memory and restoration of cognitive functions. An explanation of various stages of sleep (quick sleep and slow sleep) and their role in training and memorization. Consideration of sleep disorders, such as insomnia and apnea in a dream, and their influence on cognitive functions.
- Diet: Discussion of the effect of nutrition on the health of the brain. Consideration of key nutrients necessary for optimal cognitive function, such as omega-3 fatty acids, B vitamins, antioxidants and minerals. Discussion of the harmful effects of processed products, sugar and trans fats on the brain.
- Life: Consideration of the influence of physical activity, social interactions and mental stimulation on cognitive functions. Discussion of the advantages of regular physical exercises to improve blood circulation in the brain and stimulate neurogenesis. Consideration of the importance of social ties to maintain cognitive health. Discussion of mental exercises, such as puzzles, reading and teaching new skills.
- Genetics: A brief discussion of a genetic predisposition to some cognitive disorders, but with an emphasis on modified risk factors, such as lifestyle and nutrition.
Chapter 2: Effective dietary supplement to improve memory and concentration
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1 Nootropics:
- Definition and mechanism of action: A detailed explanation of the concept of nootropics – substances that improve cognitive functions, especially memory, training and attention. Description of various mechanisms of the action of nootropics, including an increase in blood circulation in the brain, improving neurotransmission, protection against neurotoxicity and increased neuroplasticity.
- Racetam:
- Piracetam: Overview of piracetam, the first synthesized nootropic. Description of its mechanism of action, potential advantages (improvement of memory, training, concentration) and side effects (headache, insomnia). Discussion of dosage and reception schemes.
- Aniracetam: Comparison of aniracetam with piracetam. Description of its higher bioavailability and a potentially more pronounced effect on mood and anxiety. Discussion of dosage and reception schemes.
- Oxiracetam: Comparison of oxyracetam with piracetam. Description of its stimulating effect and potential benefit to improve concentration and motivation. Discussion of dosage and reception schemes.
- Pramiracetam: Comparison of prarametam with piracetam. Description of its high potency and potential benefit for improving memory and learning. Discussion of dosage and reception schemes.
- Fenilpiracetam: Description of phenylpiRapetam, modified piracetam with the addition of a phenile group, which increases its lipophilicity and permeability through a hematoencephalic barrier. Discussion of its stimulating effect, improve the concentration of attention and physical performance. Discussion of dosage and reception schemes. Important warning about the possible development of tolerance.
- Cholengergic agents:
- Alfa-GFH (Alfa-Glycerylphosphereholin): Description of the alpha-μHfh as a source of choline necessary for the synthesis of acetylcholine. Discussion of its potential benefit for improving memory, training and concentration of attention. Discussion of dosage and reception schemes.
- Citicolin (CDP-Holin): Description of citicolin as a source of choline and citidine. Discussion of its potential benefit for improving memory, attention, cognitive functions and recovery after stroke. Discussion of dosage and reception schemes.
- DMAE (dimethylaminoethanol): Description DMAE as the predecessor of choline. Discussion of its potential benefit to improve mood, concentration and mental energy. Discussion of dosage and reception schemes. Important warning about potential side effects and the need to consult a doctor.
- Other nootropics:
- Noopept: Description of Noopepte as a synthetic nootropic, structurally similar to neuropeptide. Discussion of its potential benefit for improving memory, training, attention and mood. Discussion of dosage and reception schemes.
- Selank: Description of Selanka as a synthetic analogue of Peptide Taf (Tuftsin). Discussion of its anxiolytic (anti -aircraft) and nootropic effects. Discussion of dosage and reception schemes.
- Semax: Description of Semax as a synthetic analogue of ACTH (adrenocorticotropic hormone). Discussion of its potential benefit for improving memory, attention and training. Discussion of dosage and reception schemes.
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2 Plant adaptogens:
- Definition and mechanism of action: A detailed explanation of the concept of adaptogens – substances that increase the body’s resistance to stress and improve adaptation to adverse conditions. Description of various mechanisms of action of adaptogens, including the modulation of the hormonal system, immune system and antioxidant protection.
- Ginseng:
- Types of ginseng: Description of various types of ginseng, such as Panax Ginseng (Korean ginseng), Panax Quinquefolius (American ginseng) and Eleutherococcus senticosus (Siberian ginseng). Comparison of their chemical composition and pharmacological properties.
- Useful properties: Discussion of the potential benefits of ginseng to improve memory, concentration, mental and physical performance, reduce fatigue and stress. Discussion of dosage and reception schemes. Important warning about possible side effects and drug interactions.
- Rhodiola pink (Rhodiola rosea):
- Chemical composition: Description of the key active components of Rodiola Pink, such as Rosavin and Salidroside.
- Useful properties: Discussion of the potential benefit of Rodiola pink to improve cognitive functions, reduce fatigue, stress and anxiety, increase mood and physical performance. Discussion of dosage and reception schemes.
- Bacopa Monnieri:
- Chemical composition: Description of the key active components of the Monier Bakop, such as bacosides.
- Useful properties: Discussion of the potential benefit of Bakop Monier to improve memory, training and cognitive functions, especially with prolonged use. Discussion of dosage and reception schemes.
- Ashwaganda (withania somnifera):
- Chemical composition: Description of the key active components of Ashvaganda, such as vitanolides.
- Useful properties: Discussion of the potential benefits of Ashvaganda to reduce stress, anxiety and improve cognitive functions, especially memory and attention. Discussion of dosage and reception schemes. An important warning about possible side effects and interactions with drugs, especially with thyroid diseases.
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3 Vitamins and minerals:
- B vitamins B:
- Vitamin B1 (TIAMIN): Description of the role of vitamin B1 in the metabolism of glucose and the transmission of nerve impulses. Discussion of its deficiency and influence on cognitive functions.
- Vitamin B3 (Niacin): Description of the role of vitamin B3 in energy metabolism and the functioning of the nervous system. Discussion of its deficiency and influence on cognitive functions.
- Vitamin B5 (pantotenic acid): Description of the role of vitamin B5 in the synthesis of coenzyme A necessary for energy metabolism and the synthesis of neurotransmitters. Discussion of its deficiency and influence on cognitive functions.
- Vitamin B6 (Pyridoxin): Description of the role of vitamin B6 in the synthesis of neurotransmitters, such as dopamine, serotonin and GABK. Discussion of its deficiency and influence on cognitive functions.
- Vitamin B9 (folic acid): Description of the role of vitamin B9 in the synthesis of DNA and RNA, as well as in the metabolism of homocysteine. Discussion of its deficiency and influence on cognitive functions and the risk of dementia.
- Vitamin B12 (cobalamin): Description of the role of vitamin B12 in the functioning of the nervous system and the synthesis of myelin. Discussion of its deficiency and influence on cognitive functions, especially memory and attention. Discussion of the need to receive vitamin B12 for vegetarians and vegans.
- Vitamin D: Description of the role of vitamin D in the development and functioning of the brain. Discussion of its deficiency and connection with cognitive disorders, depression and Alzheimer’s disease. Discussion of the need to receive vitamin D, especially in winter.
- Magnesium: Description of the role of magnesium in the functioning of the nervous system and synaptic plasticity. Discussion of its deficiency and influence on cognitive functions, sleep and anxiety. Discussion of various forms of magnesium (for example, magnesium tronate) and their bioavailability.
- Zinc: Description of the role of zinc in the functioning of the nervous system, antioxidant protection and immune function. Discussion of its deficiency and influence on cognitive functions, mood and immunity.
- Iron: Description of the role of iron in the transfer of oxygen to the brain and the synthesis of neurotransmitters. Discussion of its deficiency (iron deficiency anemia) and influence on cognitive functions, fatigue and attention.
- B vitamins B:
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4 Omega-3 fatty acids:
- EY DHA: A detailed description of EPA (eicopascentenoic acid) and DHA (non-oxaexhenoic acid) as the main omega-3 fatty acids. Description of their role in the structure of cell membranes of the brain, neurotransmissance and inflammation.
- Omega-3 sources: Discussion of various sources of omega-3 fatty acids, such as fatty fish (salmon, sardins, mackerel), linen seed, chia seeds and walnuts. Discussion of the advantages and disadvantages of various sources.
- Useful properties: Discussion of the potential benefits of omega-3 fatty acids to improve memory, training, attention, mood and protection from neurodegenerative diseases. Discussion of dosage and reception schemes.
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5 Other useful dietary supplements:
- Coenzim Q10 (COQ10): Description of the role of Coenzyme Q10 in energy metabolism and antioxidant protection. Discussion of its potential benefit for improving cognitive functions and protecting against neurodegenerative diseases.
- Alpha-lipoic acid (ALA): Description of alpha-lipoic acid as a powerful antioxidant that can penetrate through a hematoencephalic barrier. Discussion of its potential benefit for improving cognitive functions and protecting against neurodegenerative diseases.
- Creatine: Description of the role of creatine in the energy metabolism of the brain. Discussion of its potential benefit for improving memory, attention and mental performance.
- Pyritinol: Description of Piritinol as a derivative of vitamin B6. Discussion of its potential benefit for improving cognitive functions and blood circulation in the brain.
- Ginkgo biloba (Ginkgo Biloba): Description of ginkgo bilobe as a plant extract that improves blood circulation in the brain and has antioxidant properties. Discussion of its potential benefit for improving memory and concentration.
Chapter 3: Rules for admission of dietary supplements and precautions
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1 Consultation with a doctor: The urgent recommendation of consultation with the doctor before taking any dietary supplements, especially in the presence of chronic diseases, medication or pregnancy. An explanation of the importance of assessing the individual state of health and possible interactions of dietary supplements with medicines.
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2 The choice of high -quality dietary supplements:
- Reputation manufacturer: Recommendations for the choice of dietary supplements from famous and reliable manufacturers with a good reputation.
- Certification: Pay attention to the availability of quality certificates confirming the safety and effectiveness of dietary supplements (for example, GMP, NSF).
- Composition: A careful study of the composition of dietary supplements and the avoidance of products with additives, dyes and artificial flavors.
- Third -party laboratory research: The preference of dietary supplements that have passed third -party laboratory tests for cleanliness and compliance with the declared composition.
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3 Dosage and reception scheme:
- Following the instructions: Strict adherence to the instructions for the dosage and the reception scheme indicated on the package of the dietary supplement.
- Start with small doses: The recommendation to start taking dietary supplements with small doses and gradually increase the dosage if necessary.
- Reception time: Discussion of the optimal time of admission of dietary supplements (for example, in the morning or evening) depending on their properties.
- Cycling: Discussion of the appropriateness of cycling of the reception of some dietary supplements (for example, nootropics) to prevent the development of tolerance.
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4 Side effects and interactions:
- Possible side effects: Description of the possible side effects of each dietary supplement, such as headache, insomnia, nausea, stomach disorder and allergic reactions.
- Interactions with drugs: A warning about the possible interactions of dietary supplements with drugs, especially with anticoagulants, antidepressants and drugs for the treatment of cardiovascular diseases.
- Continuation of reception with side effects: The recommendation immediately stop taking the dietary supplement and consult a doctor when any side effects appear.
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5 A comprehensive approach to improving cognitive functions:
- Bad as an addition: The emphasizing that dietary supplements are only an addition to a healthy lifestyle and cannot replace full nutrition, regular physical exercises, sufficient sleep and mental stimulation.
- Life: A reminder of the importance of maintaining a healthy lifestyle for an optimal cognitive function, including proper nutrition, regular physical exercises, sufficient sleep, stress and mental stimulation.
- Cognitive training: The recommendation of cognitive training, such as puzzles, games for the brain and teaching new skills, to maintain and improve cognitive functions.
Chapter 4: Research and evidence base
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1 Scientific research: A review of key scientific research confirming the effectiveness of dietary supplements to improve memory and concentration. Links to scientific articles and meta analyzes published in the reviewed magazines.
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2 Critical research assessments: Discussion of scientific research restrictions, such as small samples, lack of control groups and bias. Emphasizing the need to conduct additional research to confirm the efficiency and safety of dietary supplements.
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3 Meta-analyzes and systematic reviews: A review of meta-analyzes and systematic reviews that combine the results of several studies to assess the overall efficiency of dietary supplements.
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4 Individual results: The emphasis that the results of the use of dietary supplements can vary depending on the individual characteristics of the body, age, state of health and lifestyle.
Chapter 5: Prospects and future research
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1 New developments in the field of nootropics: A review of new developments in the field of nootropus and dietary supplements to improve cognitive functions, including studies of new compounds and mechanisms of action.
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2 Personalized nutrigenomy: Discussion of the prospects of personalized nutrigenomy – an approach based on the analysis of the genetic characteristics of a person to determine the optimal nutrition and take dietary supplements to improve cognitive functions.
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3 Clinical trials: Emphasizing the need to conduct large -scale clinical trials to evaluate the effectiveness and safety of new nootropes and dietary supplements.
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4 Ethical aspects: Discussion of ethical aspects of the use of nootropics and dietary supplements to improve cognitive functions, especially in the context of healthy people and competitive environments.
Chapter 6: Additional methods for improving memory and concentration of attention
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1 Mnemonics techniques:
- Lokusi method (memory palace): A detailed description of the method of loci, ancient mnemonics, based on visualization and association of information with specific places.
- Chain method: Description of the method of a chain based on the binding of information elements into a logical sequence or history.
- Acronyms and abbreviations method: Description of the use of acronyms and abbreviations for remembering lists and sequences.
- Method Riffm and Song: Description of the use of rhymes and songs to remember information.
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2 Meditation and Mindfulness:
- Brain effect: Description of the influence of meditation and mindfulness on the structure and function of the brain, including an increase in the volume of gray matter in the prefrontal bark and hippocampus.
- Improving attention and concentration: Discussion of the potential benefits of meditation and mindfulness to improve attention, concentration and reduce stress.
- Practical exercises: Description of simple meditation exercises and mindfulness, which can be performed daily.
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3 Cognitive training:
- Games for the brain: A review of popular brain games such as Lumosity, Cognifit and Elevate, and their potential benefits for improving cognitive functions.
- Puzzles: The recommendation of the solution of puzzles, such as Sudoku, crosswords and puzzles, to stimulate the brain and improve cognitive functions.
- Training in new skills: Description of the importance of teaching new skills, such as playing a musical instrument, learning a foreign language or art lesson, to maintain neuroplasticity and improve cognitive functions.
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4 Sleep optimization:
- Sleep hygiene: A detailed description of the rules of sleep hygiene, such as observing the regular sleep and wakefulness mode, creating a comfortable situation for sleeping, avoiding caffeine and alcohol before bedtime, and restricting the use of electronic devices before bedtime.
- Sleep disorders treatment: The recommendation of a doctor’s appeal for the diagnosis and treatment of sleep disorders, such as insomnia and apnea in a dream.
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5 Physical activity:
- Aerobic exercises: Description of the advantages of aerobic exercises, such as walking, running, swimming and riding a bicycle, to improve blood circulation in the brain and stimulate neurogenesis.
- Power exercises: Description of the advantages of strength exercises to maintain muscle mass and improve cognitive functions.
- Yoga and Tai Chi: Description of the advantages of yoga and Thai Chi to reduce stress, improve balance and cognitive functions.
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6 Social activity: Description of the importance of social interactions to maintain cognitive health and reduce the risk of dementia. Recommendation of active participation in social events, communicating with friends and family, and volunteer activities.
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