Dad for immunity: contraindications and side effects
I. Introduction: immunity and dietary supplement – a complex relationship
The immune system is a complex network of cells, tissues and organs that work together to protect the body from diseases. A healthy lifestyle, including a balanced diet, regular physical exercises and sufficient sleep, is the basis of strong immunity. However, in the modern world, when many people are faced with high stress, improper nutrition and exposure to environmental pollutants, maintaining the optimal functioning of the immune system can be a difficult task.
In this situation, many people turn to biologically active additives (Badam) for immunity, hoping to strengthen their protective forces. Bades are products designed to supplement the diet and containing vitamins, minerals, herbs, amino acids and other substances. They are available in various forms, including tablets, capsules, powders and liquids.
However, despite the wide popularity of dietary supplements for immunity, it is important to understand that they are not medicines and should not be used to treat diseases. In addition, dietary supplements can have contraindications and side effects, which you need to know before the start of admission.
In this article, we will examine in detail the most common dietary supplements used to maintain immunity, their alleged action mechanisms, contraindications and possible side effects. The purpose of this article is to provide readers with the comprehensive information necessary for making a conscious decision on the advisability of using dietary supplements for immunity.
II. Overview of the main dietary supplements for immunity
There is a wide range of dietary supplements that are advertised as means to strengthen immunity. Some of the most common include:
A. Vitamins:
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Vitamin C (ascorbic acid): One of the most famous and widely used vitamins to maintain immunity. Vitamin C is a powerful antioxidant that protects the cells from damage by free radicals. It also participates in the production of collagen, which is necessary for the health of the skin and mucous membranes, which are important barriers to penetrate infections.
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The alleged mechanism of action: Vitamin C supports the function of immune cells, such as phagocytes and T cells, and contributes to the production of antibodies. It can also reduce the duration and severity of colds.
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Contraindications: Individual intolerance, hypercoagulation, thrombophlebitis, tendency to thrombosis, diabetes mellitus (high doses). With caution in diseases of the kidneys and gastrointestinal tract.
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Side effects: With high doses, dyspeptic phenomena (nausea, vomiting, diarrhea), headache, increased excitability, sleep disturbance, increased blood pressure, formation of kidney stones (with prolonged use of high doses) are possible.
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Vitamin D (cholegalciferol): Fatable vitamin, playing an important role in the regulation of the immune system. Vitamin D helps the activation of immune cells and the production of antimicrobial peptides that help fight infections.
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The alleged mechanism of action: Vitamin D binds to vitamin D (VDR) receptors on immune cells, adjusting their function and contributing to the production of antimicrobial peptides.
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Contraindications: Hypervitaminosis D, hypercalcemia, hypercalciuria, urolithiasis, sarcoidosis, renal failure, the active form of pulmonary tuberculosis. With caution during pregnancy and breastfeeding.
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Side effects: With an overdose, nausea, vomiting, constipation, weakness, headache, increased blood pressure, heart rhythm, renal failure are possible.
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Vitamin E (Tokoferol): A powerful antioxidant that protects cells from damage by free radicals. Vitamin E also participates in the regulation of immune function and can improve the reaction of the immune system to infection.
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The alleged mechanism of action: Vitamin E protects cell membranes from oxidative damage, which can improve the function of immune cells. It can also stimulate antibodies.
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Contraindications: Individual intolerance, severe cardiosclerosis, myocardial infarction, increased risk of thromboembolism. With caution when taking anticoagulants.
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Side effects: With high doses, dyspeptic phenomena, weakness, headache, increased blood pressure, and impaired blood coagulation are possible.
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Vitamin A (Retinol): Fatable vitamin, necessary for the health of the skin, mucous membranes and immune system. Vitamin A maintains the integrity of epithelial barriers that protect the body from the penetration of infections.
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The alleged mechanism of action: Vitamin A maintains the integrity of epithelial barriers and contributes to the production of immune cells, such as T cells and B cells.
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Contraindications: Hypervitaminosis a, pregnancy (especially the first trimester), severe diseases of the liver and kidneys.
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Side effects: With an overdose, headache, nausea, vomiting, loss of appetite, dry skin, hair loss, visual impairment, hepatotoxicity are possible.
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B. Minerals:
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Zinc: An important trace element involved in many aspects of the immune function. Zinc is necessary for the development and functioning of immune cells, such as T cells, B-cells and NK cells.
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The alleged mechanism of action: Zinc is involved in the development and functioning of immune cells and contributes to the development of cytokines that regulate the immune response.
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Contraindications: Individual intolerance, renal failure. With caution when taking iron and copper preparations.
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Side effects: With high doses, dyspeptic phenomena, nausea, vomiting, diarrhea, decrease in appetite, flavor violation, and shortage of copper are possible.
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Selenium: An antioxidant that protects the cells from damage by free radicals. Selenium also plays an important role in the regulation of immune function and can improve the reaction of the immune system to infection.
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The alleged mechanism of action: Selenium is involved in the work of antioxidant enzymes that protect cells from oxidative damage. It can also stimulate antibodies.
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Contraindications: Individual intolerance. With caution when taking anticoagulants.
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Side effects: With an overdose, hair loss, fragility of nails, skin rash, nausea, vomiting, diarrhea, and garlic odor from the mouth are possible.
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Iron: An important trace element necessary for the production of hemoglobin, which tolerates oxygen to cells. Iron also plays an important role in the immune function.
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The alleged mechanism of action: Iron is necessary for the development and functioning of immune cells and promotes the production of cytokines.
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Contraindications: Hemochromatosis, hemosiderosis, anemia not associated with iron deficiency. With caution in diseases of the gastrointestinal tract.
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Side effects: When taking iron drugs, dyspeptic phenomena, constipation, nausea, vomiting, abdominal pain, darkening of feces are possible.
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C. Herbs and plant extracts:
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SOUTINATEA: One of the most popular plant tools to strengthen immunity. Echinacea contains active substances that can stimulate the immune system and help fight infections.
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The alleged mechanism of action: Echinacea stimulates phagocytosis (absorption of bacteria and other foreign substances with immune cells) and contributes to the production of cytokines.
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Contraindications: Individual intolerance, autoimmune diseases, progressive systemic diseases (tuberculosis, leukemia, multiple sclerosis), pregnancy and breastfeeding.
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Side effects: Allergic reactions (skin rash, itching, urticaria), dyspeptic phenomena, and headache are possible.
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Ginseng: Adaptogen, which can help the body adapt to stress and improve immune function. Ginseng contains active substances called ginzenosides, which have various biological effects.
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The alleged mechanism of action: Ginseng stimulates the immune system and promotes antibodies. It can also improve energy metabolism and reduce fatigue.
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Contraindications: Individual intolerance, arterial hypertension, increased excitability, insomnia, acute infectious diseases, bleeding.
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Side effects: An increase in blood pressure, headache, insomnia, dyspeptic phenomena, allergic reactions are possible.
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Garlic: It has antimicrobial and anti -inflammatory properties. Garlic contains allicin, an active substance that can kill bacteria, viruses and fungi.
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The alleged mechanism of action: Allicine contained in garlic has antimicrobial and anti -inflammatory properties. It can also stimulate the immune system.
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Contraindications: Individual intolerance, exacerbation of diseases of the gastrointestinal tract, liver and kidney disease, pregnancy and breastfeeding. With caution when taking anticoagulants.
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Side effects: Dyptic phenomena, heartburn, nausea, vomiting, unpleasant odor from the mouth, allergic reactions are possible.
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Black Buzina (Sambucus Nigra): Busy berries contain antioxidants and substances that can help reduce the duration and severity of colds and influenza.
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The alleged mechanism of action: Buzines extracts contain antioxidants and substances that can inhibit viruses replication and stimulate the immune system.
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Contraindications: Individual intolerance, pregnancy and breastfeeding. You can not use raw berries of an elderberry, as they contain cyanogenic glycosides.
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Side effects: Dyptic phenomena, nausea, vomiting, diarrhea are possible.
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D. Other dietary supplements:
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Probiotics: Living microorganisms, which, when used in sufficient quantities have a beneficial effect on the health of the owner. Probiotics can improve intestinal health, which plays an important role in the immune function.
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The alleged mechanism of action: Probiotics improve intestinal health, contribute to the growth of beneficial bacteria and suppress the growth of pathogenic bacteria. They can also stimulate the immune system.
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Contraindications: Individual intolerance, acute intestinal infections, immunodeficiency conditions. With caution in children and the elderly.
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Side effects: Dypeptic phenomena, bloating, flatulence are possible.
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Colostrum (colostrum): The first milk that is produced in mammals after childbirth. Mogamines are rich in antibodies, immune factors and growth factors.
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The alleged mechanism of action: Colostrum contains antibodies that can protect against infections. It can also stimulate the immune system and contribute to the growth and restoration of fabrics.
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Contraindications: Individual intolerance, allergies to dairy products, pregnancy and breastfeeding.
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Side effects: Diapeptic phenomena, allergic reactions are possible.
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Beta-glucan: Polysaccharides that are contained in the cell walls of mushrooms, bacteria and yeast. Beta-glucans can stimulate the immune system and improve the reaction to infection.
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The alleged mechanism of action: Beta-glucans activate immune cells, such as macrophages and NK cells, and contribute to the production of cytokines.
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Contraindications: Individual intolerance, autoimmune diseases.
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Side effects: Diapeptic phenomena, allergic reactions are possible.
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III. Risk factors and contraindications for receiving dietary supplements for immunity
Before taking dietary supplements for immunity, it is important to consider risk factors and contraindications that can increase the likelihood of developing side effects or interaction with drugs.
A. General risk factors:
- Age: Children and elderly people are more susceptible to side effects of dietary supplements. In children, the immune system is not yet fully developed, and in older people it can be weakened.
- Pregnancy and breastfeeding: Many dietary supplements are not recommended to be taken during pregnancy and breastfeeding, since their safety for the fetus or infants has not been established.
- Chronic diseases: People with chronic diseases, such as kidney diseases, liver, heart, diabetes and autoimmune diseases, should consult a doctor before taking dietary supplements.
- Taking drugs: Bades can interact with drugs by changing their effectiveness or increasing the risk of side effects.
B. Specific contraindications:
Section II described specific contraindications for each dietary supplement. It is important to carefully familiarize yourself with this information before the reception.
C. Interaction with drugs:
Bades can interact with various drugs, including:
- Anticoagulants (for example, warfarin): Some dietary supplements, such as vitamin E, garlic and ginseng, can enhance the effect of anticoagulants, increasing the risk of bleeding.
- Antiplatelet (eg, aspirin, clopidogrel): Some dietary supplements can enhance the effects of antiplatelet agents, increasing the risk of bleeding.
- Immunosuppressants (for example, cyclosporine, azathioprine): Some dietary supplements, such as echinacea, can stimulate the immune system and reduce the effectiveness of immunosuppressants.
- Antidiabetic drugs (for example, metformin, insulin): Some dietary supplements, such as ginseng, can affect blood sugar and change the need for antidiabetic drugs.
- Preparations for the treatment of cardiovascular diseases (for example, digoxin, antiarrhythmic drugs): Some dietary supplements can interact with drugs for the treatment of cardiovascular diseases and change their effectiveness or increase the risk of side effects.
IV. Side effects of dietary supplements for immunity
Side effects of dietary supplements for immunity can vary from lungs to serious and depend on the type of dietary supplement, dose, duration of admission and individual susceptibility.
A. The most common side effects:
- Dyspeptic phenomena: Nausea, vomiting, diarrhea, constipation, abdominal pain, heartburn, bloating, flatulence.
- Allergic reactions: Skin rash, itching, urticaria, Quincke’s edema, anaphylactic shock (rarely).
- Headache:
- Insomnia:
- Improving blood pressure:
- Interaction with drugs: Changing the effectiveness of drugs or increasing the risk of side effects.
B. Rare but serious side effects:
- Liver damage:
- Kidney damage:
- Bleeding:
- Cardiac violation:
- Autoimmune reactions: (rarely)
- Anaphylactic shock: (very rarely)
V. Recommendations for the safe reception of dietary supplements for immunity
To minimize the risk of side effects and ensure safe intake of dietary supplements for immunity, the following recommendations should be observed:
- Consult a doctor: Before taking dietary supplements, be sure to consult a doctor to make sure that they are safe for you and will not interact with your drugs.
- Choose quality products: Bad only from trusted manufacturers and in reliable pharmacies or stores. Pay attention to the certification of products and the availability of information about the composition and dosage.
- Follow the recommended doses: Do not exceed the recommended doses indicated on the product label or recommended by the doctor.
- Start with low doses: Start with a low dose of bad and gradually increase it, if necessary, to evaluate your tolerance.
- Carefully follow your condition: If you notice any side effects, stop taking a dietary supplement and consult a doctor.
- Tell the doctor about all the dietary supplements: When visiting a doctor, be sure to inform him of all the dietary supplements that you accept so that he can take into account possible interactions with drugs.
- Be especially careful during pregnancy and breastfeeding: Most dietary supplements are not recommended to be taken during pregnancy and breastfeeding. Consult a doctor before starting taking any dietary supplements during this period.
- Do not use dietary supplements to treat diseases: Bades are not medicines and should not be used to treat diseases. If you are sick, consult a doctor to receive medical care.
- Remember a healthy lifestyle: Bades can be a useful addition to a healthy lifestyle, but they do not replace a balanced diet, regular physical exercises and sufficient sleep.
VI. Badam alternatives to maintain immunity
Instead of relying exclusively on dietary supplements to maintain immunity, consider the following alternative approaches that can be more effective and safe:
- Balanced nutrition: Use a variety of products rich in vitamins, minerals, antioxidants and fiber. Include fruits, vegetables, whole grain products, legumes, nuts, seeds and low -fat protein sources in your diet.
- Regular physical exercises: Regular physical exercises can strengthen the immune system and reduce the risk of diseases. Try to engage in moderate physical activity at least 150 minutes a week.
- Sufficient sleep: The lack of sleep can weaken the immune system. Try to sleep at least 7-8 hours a day.
- Stress management: Chronic stress can weaken the immune system. Use relaxation techniques such as meditation, yoga or breathing exercises to control stress.
- Refusal of smoking and restriction of alcohol use: Smoking and excessive alcohol consumption can weaken the immune system.
- Compliance with hygiene rules: Wash your hands with soap and water regularly, especially after visiting public places and before eating.
- Vaccination: Vaccination is an effective way to protect against infectious diseases. Discuss with your doctor what vaccines you need.
VII. Conclusion
Bad for immunity can be a useful addition to a healthy lifestyle, but they are not medicines and should not be used to treat diseases. It is important to understand that dietary supplements can have contraindications and side effects that you need to know about before the start of the reception.
Before you start taking any dietary supplements for immunity, be sure to consult a doctor to make sure that they are safe for you and will not interact with your drugs. Follow the recommended doses and carefully monitor your condition.
Instead of relying exclusively on dietary supplements to maintain immunity, consider alternative approaches, such as balanced nutrition, regular physical exercises, sufficient sleep, stress and compliance with hygiene rules. These approaches can be more effective and safe to strengthen the immune system.
VIII. List of literature
- National Institutes of Health (NIH). Office of Dietary Supplements. Vitamin C. https://ods.od.nih.gov/factsheets/VitaminC-HealthProfessional/
- National Institutes of Health (NIH). Office of Dietary Supplements. Vitamin D. https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/
- National Institutes of Health (NIH). Office of Dietary Supplements. Zinc. https://ods.od.nih.gov/factsheets/Zinc-HealthProfessional/
- Echinacea. National Center for Complementary and Integrative Health (NCCIH). https://www.nccih.nih.gov/health/echinacea
- Probiotics. National Center for Complementary and Integrative Health (NCCIH). https://www.nccih.nih.gov/health/probiotics-what-you-need-to-know
- European Food Safety Authority (EFSA). Scientific Opinion on the substantiation of health claims related to vitamin C and protection of DNA, proteins and lipids from oxidative damage (ID 129, 138, 139, 149), maintenance of normal immune function (ID 134, 343), contribution to normal energy-yielding metabolism (ID 135, 145), maintenance of the normal function of the nervous system (ID 133), maintenance of normal collagen formation (ID 129, 138, 139, 149), reduction of tiredness and fatigue (ID 136, 146), increase of non-haem iron absorption (ID 132) and regeneration of the reduced form of vitamin E (ID 148) pursuant to Article 13(1) of Regulation (EC) No 1924/2006. EFSA Journal 2009; 7(9):1226.
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