The article should be written in Russian.
Dietrs for the joints: myths and reality
Section 1: Anatomy and joint physiology – understanding of the basics
To evaluate the effectiveness and necessity of dietary supplements for joints, it is important to understand how these complex structures are arranged and function. The joint is a mobile connection of two or more bones, providing freedom of movement. The key joint components are:
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Cartilage: Smooth, elastic fabric covering the ends of the bones in the joint. It acts as a shock absorber, reducing friction and providing smooth gluing of bones relative to each other. The cartilage consists mainly of water, collagen and proteoglycans, including chondroitin sulfate and glucosamine. The cartilage does not have blood vessels, so its nutrition is carried out due to the synovial fluid.
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Synovial fluid: A viscous fluid filling the joint cavity. It serves as a lubricant, reducing friction, and provides nutrition of cartilage. The synovial fluid contains hyaluronic acid, which provides its viscosity and elasticity.
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The joint capsule: Strong fibrous membrane surrounding the joint. It provides joint stability and holds the synovial fluid inside.
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Blues: Hard strips of connective tissue connecting the bones to each other. They provide joint stability and limit its movements in certain directions.
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Muscles and tendons: The muscles surrounding the joint provide movement. Tendons are a connective tissue that attaches the muscles to the bones.
Joint damage mechanisms:
Various factors can lead to damage to the joints and the development of diseases, such as osteoarthritis (osteoarthrosis), rheumatoid arthritis and other arthropathy. The main mechanisms include:
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Exporting Horseback: The gradual destruction of the cartilage due to aging, excessive load, injuries or genetic predisposition. This leads to the exposure of bones, friction and inflammation.
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Inflammation: Activation of the immune system in the joint, leading to the release of inflammatory substances that damage cartilage and other tissues. Inflammation can be caused by autoimmune diseases, infections or injuries.
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Violation of blood supply: Inadequate blood supply to the joint can lead to a deterioration in the nutrition of cartilage and its degeneration.
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Injuries: Direct strikes, dislocations, ligaments and fractures can damage the joint and lead to the development of arthritis in the future.
Section 2: Review of common joint diseases
Knowing common joint diseases helps to understand what problems the dietary supplement can solve, and how effective they are in each case.
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Osteoarthritis (osteoarthritis): The most common joint disease, characterized by progressive destruction of cartilage. Symptoms include pain, stiffness, crunch in the joint and limitation of mobility. Risk factors include age, obesity, injury, genetic predisposition and repeating movements.
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Rheumatoid arthritis: Autoimmune disease in which the immune system attacks its own joint tissue, causing inflammation, pain, stiffness and deformation. Rheumatoid arthritis can affect several joints at the same time and lead to disability.
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Gout: Inflammatory disease caused by the accumulation of uric acid crystals in the joints. Most often it affects the thumb of the foot, but can affect other joints. Symptoms include acute pain, redness and joint swelling.
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Bursit: Inflammation of the synovial bag (Bursa) – a small bag filled with liquid, which is between bones, tendons and muscles. Bursitis causes pain, swelling and limitation of mobility in the area of the affected joint.
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Tendinitis: Inflammation of the tendon caused by excessive load, repeating movements or injury. Tendinite causes pain during movement and pain on palpation of the affected tendon.
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System red lupus (SLE): Another autoimmune disease that can affect various organs and systems, including joints. SLE can cause pain, stiffness and inflammation in the joints, similar to rheumatoid arthritis.
Section 3: What are dietary supplements and how do they differ from drugs?
Biologically active additives (dietary supplements) are concentrates of natural or identical to natural biologically active substances, designed for direct intake with food or introduction into food products in order to enrich the ration with individual food or biologically active substances or complexes of such substances.
The main differences in dietary supplements and medicines:
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Appointment: Bades are designed to maintain health and prevention of diseases, and not for treatment. Medicines are used to treat specific diseases and relieve symptoms.
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Regulation: Bades are subject to less strict regulation than medicines. For the withdrawal to the Bad market, clinical tests confirming its effectiveness and safety are not required.
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Dosage and composition: The composition of dietary supplements can vary from party to party, and the dosage of active substances is not always indicated. The composition of the drugs is strictly regulated and controlled.
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Evidence base: The effectiveness of drugs should be proved during clinical trials. For dietary supplements, the presence of an evidence base is not a prerequisite.
Section 4: The main components of dietary supplements for the joints and their estimated action
The market for joints offers a wide range of products containing various components. The most common of them:
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Glucosamine: Aminosahar, which is a building block for cartilage. It is assumed that glucosamine helps to restore cartilage and reduces pain in osteoarthritis.
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Chondroitin sulfate: Another important component of cartilage that holds water and provides its elasticity. It is assumed that chondroitin sulfate protects cartilage from destruction and reduces inflammation.
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Methyl sulfonylmetatan (MSM): The source of sulfur, which is necessary for the synthesis of collagen and other important molecules in cartilage. It is assumed that MSM has anti -inflammatory properties and reduces pain.
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Hyaluronic acid: The main component of the synovial fluid that provides its viscosity and lubricates the joint. It is assumed that hyaluronic acid improves joint mobility and reduces pain.
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Collagen: The main protein of connective tissue, including cartilage, ligaments and tendons. It is assumed that the intake of collagen helps to strengthen the joints and reduce pain. There are several types of collagen, and for joints the most important collagen type II.
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Curcumin: The active ingredient of turmeric has anti -inflammatory and antioxidant properties. It is assumed that Kurkumin reduces pain and inflammation in the joints.
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Omega-3 fatty acids: Polyunsaturated fatty acids contained in fish oil and some vegetable oils. It is assumed that omega-3 fatty acids have anti-inflammatory properties and reduce joint pain.
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Vitamin D: It is important for the health of bones and joints. Vitamin D deficiency can increase the risk of osteoarthritis and other joint diseases.
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Boswelia (Boswellia Serrata): Plant extract used in traditional medicine for the treatment of inflammatory diseases. It is assumed that the Boswielia has anti -inflammatory properties and reduces joint pain.
Section 5: Scientific research on the effectiveness of dietary supplements for joints: Review of evidence
The question of the effectiveness of dietary supplements for joints is the subject of numerous scientific research. The results of these studies are often contradictory and depend on the components used, dosage, duration of the reception and design of the study.
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Glucosamine and chondroitin: Many studies have shown that glucosamine and chondroitin can slightly reduce pain and improve joint function in patients with osteoarthritis, especially in the knees. However, the effect is often small and not always clinically significant. Some studies have not discovered any difference between the intake of glucosamine and chondroitin and the use of placebo. A major study by Gait (Glucosamine/Chondroitin Arthritis International Trial), conducted by the US National Institute of Health, showed that glucosamine and chondroitin can be effective for the subgroup of patients with moderate and severe knee pain. However, for most patients, the effect was insignificant. The meta-analyzes that combine the results of several studies also give ambiguous results.
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MSM: Some studies show that MSM can reduce pain and improve joint function in patients with osteoarthritis. However, additional studies are needed to confirm these results.
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Hyaluronic acid: Intra -articular injections of hyaluronic acid (hyaluronic implants) showed their effectiveness in relief of pain and improving the function of the knee joint in patients with osteoarthritis. However, the effectiveness of the oral administration of hyaluronic acid has been less studied, and the results of studies are contradictory. Some studies show that the oral intake of hyaluronic acid can improve cartilage hydration and reduce pain, but additional studies are needed.
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Collagen: Some studies show that taking type II collagen can reduce pain and improve joint function in patients with osteoarthritis and rheumatoid arthritis. It is assumed that type II collagen can modulate an immune response and reduce inflammation in the joints. However, additional studies are needed to confirm these results and determine the optimal dosage and duration of admission.
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Curcumin: Studies have shown that Kurkumin can reduce pain and joint inflammation in patients with osteoarthritis and rheumatoid arthritis. Kurkumin has powerful anti -inflammatory properties and can inhibit the activity of enzymes involved in inflammation. However, the bioavailability of curcumin is limited, therefore, to achieve the therapeutic effect, it is necessary to use special forms of curcumin with improved bioavailability.
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Omega-3 fatty acids: Studies have shown that omega-3 fatty acids can reduce pain and joint inflammation in patients with rheumatoid arthritis and other inflammatory joint diseases. Omega-3 fatty acids have anti-inflammatory properties and can modulate an immune response. To achieve the therapeutic effect, it is necessary to take quite high doses of omega-3 fatty acids.
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Vitamin D: Studies have shown that vitamin D deficiency can increase the risk of osteoarthritis and other joint diseases. Taking vitamin D can improve the health of bones and joints, especially in people with vitamin D.
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Boswellia: Studies have shown that Boswielia can reduce pain and joint inflammation in patients with osteoarthritis and rheumatoid arthritis. Bosvelia contains bosvelic acids that have anti -inflammatory properties.
It is important to note:
- The research results are often contradictory, and additional studies are needed to confirm the effectiveness of dietary supplements for the joints.
- The effect of dietary supplements can vary from person to person and depends on the individual characteristics of the body.
- Bades are not replaced by drugs and should not be used for self -medication.
- Before taking dietary supplements, you need to consult a doctor.
Section 6: Myths about the dietary supplement for joints
There are many myths related to the joints for the joints that need to be dispelled.
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Myth 1: Bades are a natural alternative to drugs. Although many dietary supplements contain natural ingredients, this does not mean that they are safe or effective. Some dietary supplements may contain impurities or interact with medicines. In addition, “natural” does not always mean safe.
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Myth 2: Dietary supplements are guaranteed to heal arthritis. No dietary supplement can cure arthritis. Bades can only relieve symptoms and improve the joint function in some cases.
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Myth 3: The larger the dose, the better the effect. Reception of dietary supplements in high doses can be dangerous and lead to side effects. It is necessary to observe the recommended dosage indicated on the packaging, or prescribed by a doctor.
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Myth 4: All dietary supplements are equally effective. The effectiveness of the dietary supplement depends on its composition, the quality of the ingredients and the individual characteristics of the body. Some dietary supplements can be more effective than others.
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Myth 5: Bades are safe because they are sold without a recipe. The lack of a recipe does not guarantee dietary supplement safety. Some dietary supplements can interact with medicines or be dangerous for people with certain diseases.
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Myth 6: Reviews on the Internet are a reliable source of information about the effectiveness of Bad. Reviews on the Internet can be subjective and not reflect the real effectiveness of dietary supplements. Some reviews can be fabricated or paid by manufacturers. It is necessary to critically evaluate the information received from the Internet.
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Myth 7: If dietary supplement helped one person, he will not help anyone. The effectiveness of dietary supplements, like drugs, is individual. What did not work for one person may be effective for another. There are many reasons for this: a different degree of joint damage, various metabolism, concomitant diseases, etc.
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Myth 8: Bades are absolutely harmless, since they are “natural”. Even natural components can cause allergic reactions or side effects, especially with prolonged use or in large doses.
Section 7: The reality of the dietary supplements for the joints: when they can be useful and when not
The reality is that dietary supplements for joints can be useful in some cases, but are not a panacea. They will not replace the full treatment prescribed by a doctor, but may become an addition to him.
When dietary supplements can be useful:
- As an addition to the main treatment of osteoarthritis. Glucosamine, chondroitin, MSM, curcumin and other dietary supplements can help reduce pain and improve joint function in patients with osteoarthritis, in addition to drugs, physiotherapy and other treatment methods.
- For the prevention of joint diseases in people with high risk. People with overweight involving sports or having a genetic predisposition to joint diseases, dietary supplements can help slow down the destruction of cartilage and prevent the development of arthritis.
- To maintain joint health in old age. With age, the cartilage loses its elasticity and the ability to restore. Bades can help slow down this process and maintain joint mobility.
- To relieve symptoms of inflammatory joint diseases (in addition to drug therapy). Omega-3 fatty acids, curcumin and bosvel can help reduce inflammation and pain in patients with rheumatoid arthritis and other inflammatory joint diseases.
When dietary supplements do not help:
- As a replacement for drugs with serious joint diseases. Bades cannot cure rheumatoid arthritis, gout or other serious joint diseases. In these cases, you must consult a doctor and follow his recommendations.
- In the absence of effect after prolonged administration. If after 2-3 months of admission of Bad there is no improvement, it is necessary to stop taking it and consult a doctor.
- In the presence of contraindications or side effects. Before taking a dietary supplement, you need to make sure that there are no contraindications and consult a doctor, especially if you have any chronic diseases or take other medicines.
- With advanced stages of osteoarthritis with severe destruction of cartilage. In such cases, dietary supplements may be ineffective, and surgical intervention may be required.
Section 8: Safety of dietary supplements for joints: side effects and contraindications
Although dietary supplements are considered relatively safe, they can cause side effects and have contraindications.
The most common side effects:
- Digestive disorders: Nausea, vomiting, diarrhea, constipation, abdominal pain.
- Allergic reactions: Skin rash, itching, Quincke’s edema.
- Headache.
Contraindications:
- Individual intolerance to dietary supplements.
- Pregnancy and breastfeeding.
- Childhood.
- Some diseases (for example, blood coagulation disorders, kidney and liver disease).
Important:
- Before taking Bad, you must carefully study the composition and make sure that there are no allergies to components.
- Do not exceed the recommended dosage.
- When side effects appear, it is necessary to stop taking the dietary supplement and consult a doctor.
- With caution, dietary supplements should be taken to patients taking anticoagulants (for example, warfarin) or other drugs that can interact with dietary supplements.
- In the presence of chronic diseases, it is necessary to consult a doctor before taking Bad.
Section 9: How to choose high -quality dietary supplements for the joints: expert advice
The choice of high -quality dietary supplements for the joints is an important task that requires an attentive approach. Follow these tips to make the right choice:
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Pay attention to the composition. Study the composition of the dietary supplement and make sure that it contains components whose effectiveness is confirmed by scientific research (glucosamine, chondroitin, MSM, type II collagen, curcumin, omega-3 fatty acids, etc.).
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Check the availability of quality certificates. Make sure that the dietary supplement is certified by an independent organization, for example, NSF International or USP. The presence of a certificate confirms that the product meets quality and safety standards.
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Choose famous brands. Give preference to dietary supplements from famous and reliable manufacturers who have a good reputation in the market.
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Study consumer reviews. Read consumer reviews about the dietary supplement on the Internet, but remember that they can be subjective.
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Consult a doctor. Before taking Bad, consult a doctor to make sure that he is safe for you and does not interact with other medicines that you take.
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Avoid products with dubious ingredients and high promises. Be careful with dietary supplements that contain ingredients that are not confirmed by scientific research, or promise incredible results.
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Pay attention to the release form. Bades are available in various forms: tablets, capsules, powders, liquids. Choose the form that is most convenient for you.
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Compare prices. Compare the prices of dietary supplements from different manufacturers, but do not choose the cheapest option. The quality of the ingredients and the production process can affect the price.
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Pay attention to the expiration date. Make sure that dietary supplements have not expired.
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Remember individual characteristics. What is suitable for one person may not be suitable for another. Listen to your body and pay attention to any side effects.
Section 10: Alternative approaches to maintaining joint health
In addition to taking dietary supplements, there are other, more effective and scientifically based approaches to maintaining joint health.
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Regular physical exercises: Moderate physical exercises, such as walking, swimming, cycling and yoga, strengthen the muscles around the joints, improve blood supply and flexibility of the joints. It is important to avoid excessive joint load.
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Weight control: Excessive weight creates an additional load on the joints, especially the knee and hip. Weight reduction can significantly reduce pain and improve the function of the joints.
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Proper nutrition: A balanced diet rich in fruits, vegetables, whole grain products and low -fat protein provides the body with the necessary nutrients for joint health. It is important to consume enough calcium, vitamin D and omega-3 fatty acids.
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Physiotherapy: Physiotherapy can help improve joint function, reduce pain and inflammation. The physiotherapist can develop an individual exercise program adapted to your needs.
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Using orthoses and auxiliary tools: Orthes (for example, knee pads) and auxiliary products (for example, cane) can help reduce the load on the joints and relieve pain.
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Injections of corticosteroids: Injections of corticosteroids can temporarily reduce pain and inflammation in the joint, but do not solve the problem in the long term.
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Intra -articular injections of hyaluronic acid: Injections of hyaluronic acid can improve the lubrication of the joint and reduce pain in patients with osteoarthritis.
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Surgical intervention: In severe cases of osteoarthritis, a joint replacement may be required.
Section 11: The role of a doctor in the choice of dietary supplements for the joints
Consulting with a doctor is a critical step before taking any dietary supplements, especially for the joints. The doctor can evaluate your state of health, determine the cause of pain in joints, exclude serious diseases and give individual recommendations for treatment and prevention.
Why is it necessary to consult a doctor:
- Diagnosis. Joint pain can be a symptom of various diseases, from osteoarthritis to rheumatoid arthritis and gout. Only a doctor can make an accurate diagnosis and prescribe the appropriate treatment.
- Exclusion of contraindications. The doctor can evaluate your state of health and exclude contraindications to the reception of certain dietary supplements.
- Prevention of drug interactions. The doctor can evaluate how dietary supplements can interact with other drugs that you take and prevent unwanted side effects.
- Individual selection of dietary supplements. The doctor may recommend a dietary supplement that is most suitable for your specific case, taking into account your individual characteristics and health status.
- Efficiency control. The doctor can control the effectiveness of dietary supplements and adjust the dosage or treatment regimen if necessary.
- Obtaining information about other treatment methods. The doctor can talk about other, more effective methods of treating joint diseases, such as physiotherapy, exercises, medicines and surgical intervention.
- Objective assessment of the state. Internet resources and advertising can be biased and give false hopes. The doctor will provide you with reliable and scientifically sound information.
What to ask the doctor:
- What dietary supplements can be useful in my case?
- What is the recommended dosage and duration of admission?
- Are there any side effects or contraindications?
- How will diet be interacting with other medicines that I take?
- What other treatment methods can I use to relieve joint pain?
- When should I see a doctor if my condition worsens?
Section 12: future areas of research in the field of dietary supplements for joints
Despite the existing studies, there are many questions unanswered regarding the efficiency and safety of dietary supplements for the joints. Future research should be aimed at:
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Carrying out large -scale, well -planned clinical trials. Larger and high -quality studies are needed to confirm the efficiency and safety of dietary supplements for the joints. Studies should include control groups, placebo and long -term observation.
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The study of the mechanisms of the action of dietary supplements at the molecular level. It is necessary to better understand how dietary supplements act on cartilage, synovial fluid and other components of the joint.
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Development of individual approaches to the use of dietary supplements. It is necessary to take into account the individual characteristics of the body, the degree of damage to the joints and other factors when choosing a dietary supplement and determining the dosage.
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Development of new forms of producing dietary supplements with improved bioavailability. It is necessary to develop new forms of prolonged dietary supplements, which are better absorbed by the body and provide a higher concentration of active substances in the joints.
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Studying the interaction of dietary supplements with medicines. It is necessary to study how dietary supplements interact with drugs that patients take to treat joint diseases and other conditions.
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The study of the effect of dietary supplements on the progression of joint diseases. It is necessary to study whether dietary supplements can slow down the progression of osteoarthritis and other joint diseases.
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The study of the effect of dietary supplements on the quality of life of patients with joint diseases. It is necessary to study whether dietary supplements can improve the quality of life of patients with joint diseases, reducing the pain by improving the function of the joints and increasing the level of activity.
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The use of new technologies in dietary supplements. It is necessary to use new technologies, such as genomics, proteomics and metabolomics, to study the influence of dietary supplements at the molecular level.
Only with the help of further research can it be possible to obtain more accurate and scientifically sound answers to questions about the effectiveness and safety of dietary supplements for the joints and develop more effective methods of treating and prevention of joint diseases.