Collagen in dietary supplements: which is better absorbed
Section 1: What is collagen and why is it important?
Collagen is a fibrillar protein, which is the main structural component of connective tissue in the body of the human and animals. It accounts for about 30% of the total mass of protein in the body and is responsible for the strength, elasticity and elasticity of tissues, such as leather, bones, cartilage, tendons, ligaments, blood vessels and even the cornea of the eye. The name “collagen” comes from the Greek word “
Collagen is synthesized by fibroblasts, connective tissue cells that produce protein collagen molecules. Collagen synthesis is a complex process that requires the participation of various vitamins, minerals and amino acids, such as vitamin C, Prain, Lizin and glycine. With age, collagen synthesis slows down, which leads to age -related changes, such as wrinkles, loss of skin elasticity, joint pain and a decrease in bone density.
1.1 Collagen structure
The collagen molecule has a unique structure, which is a triple spiral formed by three polypeptide chains called alpha-phones. Each alpha cod consists of a repeating sequence of amino acids, in which glycine usually occupies every third position. The most common sequence is Gly-XY, where X and Y are often represented by a project and hydroxyproline, respectively. Hydroxyproline is a modified amino acid formed as a result of hydroxylation of a proline with the participation of vitamin C.
The triple spiral provides collagen with high strength and resistance to stretching. Several collagen molecules are combined, forming collagen fibrils, which then gather in larger collagen fibers. These fibers form a three -dimensional network that provides structural support for the tissues of the body.
1.2 Types of collagen
There are about 28 different types of collagen, each of which has its own specific structure and function. However, the most common and important types are:
- Type and: The most common type of collagen is about 90% of the total collagen in the body. It is contained in the skin, bones, tendons, ligaments, teeth and blood vessels. He is responsible for the strength and elasticity of these tissues.
- Type II: The main type of collagen contained in cartilage. It provides shock absorption and smooth sliding of the articular surfaces.
- Type III: Contained in the skin, muscles, blood vessels and internal organs. It plays an important role in the healing of wounds and maintaining the structure of organs.
- Type IV: The main component of basal membranes, thin layers supporting epithelial and endothelial cells. It provides structural support and filtering.
- Type V: Contained in the skin, hair and placenta. It participates in the formation of collagen fibers and regulates their structure.
1.3 The role of collagen in the body
Collagen plays a vital role in maintaining the health and functioning of various organs and systems of the body. Its main functions include:
- Support for the structure of the skin: Collagen provides elasticity, elasticity and moisturizing the skin, preventing the formation of wrinkles and supporting its youth.
- Strengthening bones: Collagen forms the basis of bone tissue, ensuring its strength and resistance to fractures.
- Maintaining joint health: Collagen is the main component of cartilage, providing depreciation and smooth sliding of the joint surfaces, preventing the development of osteoarthritis and other joint diseases.
- Strengthening tendons and ligaments: Collagen provides the strength and elasticity of the tendons and ligaments connecting the muscles with bones and bones with bones, respectively.
- Maintaining the health of blood vessels: Collagen is a component of the walls of blood vessels, ensuring their strength and elasticity, preventing the development of atherosclerosis and other cardiovascular diseases.
- Improving digestion: Collagen can maintain the health of the intestinal mucosa, improving digestion and absorption of nutrients.
- Support for the immune system: Collagen is involved in the regulation of an immune response and can help in the fight against infections.
Section 2: Sources of collagen for dietary supplements
Collagen for the production of biologically active additives (dietary supplements) is obtained from various sources, mainly animal origin. The most common sources are:
- Cattle (cows): Collagen from cow raw materials, including skin, bones and cartilage, is one of the most affordable and common sources. It contains mainly collagen types I and III, which are useful for the skin, bones and muscles.
- Pigs: Collagen made of pork leather and bones is also a common source. It contains mainly collagen types I and III, similar to the cow collagen.
- Fish (sea collagen): Collagen extracted from leather, bones and scales of fish is a popular choice due to its high bioavailability and lower risk of allergic reactions compared to collagen from cattle or pigs. Sea collagen consists mainly of type I collagen, which is useful for the skin.
- Bird (chicken collagen): Collagen made of chicken, especially sternum, is a rich source of type II collagen, which is important for joint health.
- Eggs: Egg shell membranes contain various types of collagen, including types I, V and X. They are used in dietary supplements to maintain the health of the skin, joints and connective tissue.
2.1 differences between collagen sources
Various sources of collagen differ in their composition of amino acids, the types of collagen and the degree of bioavailability. These differences can affect the effectiveness of collagen additives for various purposes.
- Cow and pork collagen: These sources are rich in collagen of types I and III, which makes them suitable for maintaining the health of the skin, bones and muscles. However, some people may experience allergic reactions to beef or pork.
- Sea collagen: Sea collagen has a lower molecular mass compared to collagen from cattle or pigs, which can improve its absorption. It is also considered a more environmentally friendly source.
- Chicken collagen: Chicken collagen is an excellent source of type II collagen, which specifically supports joint health. It is often used in dietary supplements for the treatment of osteoarthritis and other joint diseases.
- Egg collagen: Egg collagen contains a mixture of various types of collagen and can be useful for the overall health of connective tissue.
2.2 Ethical and environmental considerations
When choosing a collagen additive, it is important to consider ethical and environmental aspects related to the source of collagen.
- Sustainable agriculture and fishing: Choose products obtained from animals grown in accordance with the principles of sustainable agriculture, or from fish caught in accordance with the principles of sustainable fishing.
- Brief handling of animals: Make sure that the collagen was received from animals that were addressed humanely.
- Ecological trace: Consider the environmental trace of various sources of collagen, including greenhouse gas emissions, water consumption and the use of land. Sea collagen is often considered a more environmentally friendly option.
Section 3: Collagen forms in dietary supplements
Collagen is represented in dietary supplements in various forms, each of which has its own characteristics regarding assimilation and effectiveness. The most common forms of collagen include:
- Hydrolyzed collagen (collagen peptides): This is the most common form of collagen in dietary supplements. Hydrolysis is the process of splitting collagen molecules into smaller fragments called peptides using enzymes or acids. This facilitates the absorption of collagen by the body.
- Non-unauthorized collagen type II (UC-II): This is a form of collagen, which retains its natural triple spiral structure. It is considered more effective for maintaining joint health, since it interacts with the immune system and helps reduce inflammation in the joints.
- Gelatin: This is a form of collagen obtained by partial hydrolysis of collagen. It has a gel -like consistency and is often used in the food industry. Gelatin can be useful for the health of the intestine, but its assimilation can be less effective compared to the hydrolyzed collagen.
3.1 hydrolyzed collagen (collagen peptides): Advantages and features
The hydrolyzed collagen, also known as collagen peptides, is the most popular form of collagen in dietary supplements due to its high bioavailability and versatility.
- Improved assimilation: The process of hydrolysis breaks down the collagen molecules into smaller peptides, which are easier to absorb into the bloodstream and reach target tissues.
- Collagen synthesis stimulation: Collagen peptides stimulate fibroblasts, cells responsible for the synthesis of collagen, increasing the production of collagen in the skin, bones and joints.
- Various health benefits: Hydrolyzed collagen can have a wide range of favorable health effects, including improving skin elasticity, reduction of wrinkles, strengthening bones, relief of joint pain and improving the health of the intestine.
- Easy to use: The hydrolyzed collagen is easily dissolved in water and other liquids, which makes it convenient for adding to drinks, smoothies and other products.
3.2 Nonuinatured collagen type II (UC-II): mechanism of action and advantages
The non-reinvented collagen type II (UC-II) differs from hydrolyzed collagen with its mechanism of action and specific advantages for joint health.
- The mechanism of immune modulation: UC-II interacts with the immune system in the intestines, reducing inflammation in the joints. It contributes to the “oral tolerance”, the process in which the immune system ceases to attack the collagen in cartilage.
- Reducing joint pain and improvement of mobility: UC-II is clinically proven that reduces joint pain, improves mobility and flexibility in people with osteoarthritis and other joint diseases.
- Lower dosage: UC-II is usually taken in much less doses than a hydrolyzed collagen, usually about 40 mg per day.
3.3 Gelatin: Provitations and Restrictions
Gelatin is a partially hydrolyzed form of collagen, which has a gel -like consistency.
- Lower cost: Gelatin is usually cheaper than a hydrolyzed collagen.
- Intestinal health: Gelatin can be useful for the health of the intestine due to the content of amino acids, such as glycine and praise, which support the health of the intestinal mucosa.
- Less effective assimilation: The assimilation of gelatin can be less effective in comparison with a hydrolyzed collagen, since collagen molecules are not split into such small peptides.
- Inconvenience of use: Gelatin can be less convenient to use than a hydrolyzed collagen, since it requires dissolution in hot water and can form lumps.
Section 4: Factors affecting the assimilation of collagen
The assimilation of collagen depends on a number of factors, including the form of collagen, the source of collagen, individual characteristics of the body and the presence of other nutrients.
4.1 molecular weight of collagen
The molecular weight of collagen plays an important role in its assimilation. Collagen with a lower molecular mass, such as a hydrolyzed collagen, is easier to suck into the bloodstream than collagen with a higher molecular weight, such as gelatin.
4.2 Collagen source
Various sources of collagen may differ in bioavailability. Sea collagen, as a rule, has a lower molecular mass and can be better absorbed compared to collagen from cattle or pigs.
4.3 Individual characteristics of the body
Individual factors, such as age, state of health and digestive function, can affect the absorption of collagen. In the elderly and people with diseases of the digestive system, the assimilation of collagen can be reduced.
4.4 The presence of other nutrients
The presence of certain nutrients, such as vitamin C, amino acids (praise, lysine and glycine) and minerals (copper and zinc), is necessary for the synthesis of collagen. Vitamin C is an important cofactor for enzymes participating in the hydroxylating of the proline and lysine, necessary for the formation of a stable triple collagen spiral. Amino acids, such as Prain, Lizin and Glycine, are building collagen blocks. Minerals, such as copper and zinc, are involved in the formation of collagen fibers.
4.5 Combination of collagen with vitamin C
The joint use of collagen with vitamin C can significantly improve the absorption and effectiveness of collagen. Vitamin C is necessary for collagen synthesis and helps strengthen collagen fibers.
Section 5: How to choose the best collagen supplement for assimilation
When choosing a collagen additive for optimal assimilation, the following factors should be taken into account:
- Choose a hydrolyzed collagen (collagen peptides): This is the most absorbed form of collagen.
- Consider the source of collagen: Sea collagen can be more preferable due to its lower molecular mass and high bioavailability.
- Look for additives containing vitamin C: Vitamin C improves collagen absorption and stimulates collagen synthesis.
- Pay attention to the quality and purity of the product: Choose products from reliable manufacturers who have been tested for cleanliness and safety.
- Consider your individual needs: If you have joint diseases, consider the possibility of taking a non-aatured collagen type II (UC-II).
5.1 Reading labels and composition analysis
It is important to carefully read the labels and analyze the composition of collagen additives to make sure that they contain the necessary ingredients and do not contain harmful additives.
- The amount of collagen per portion: Pay attention to the amount of collagen contained in each portion. The recommended dose of collagen varies depending on the purpose of use.
- Type of collagen: Make sure the additive contains a type of collagen suitable for your needs. For example, for joint health it is better to choose additives with a collagen type II.
- Other ingredients: Check the presence of other ingredients such as vitamin C, hyaluronic acid and antioxidants that can improve the absorption and effectiveness of collagen.
- Lack of harmful additives: Avoid additives containing artificial dyes, flavors, preservatives and other harmful additives.
5.2 Choosing a reliable manufacturer
The choice of a reliable manufacturer is crucial for ensuring the quality and safety of the collagen supplement.
- Company reputation: Explore the reputation of the company and check for consumer reviews.
- Quality certificates: Look for products that have quality certificates such as GMP (good manufactoring practices) or NSF International.
- Testing Third side: Make sure that the products have been tested by the third party to cleanliness, safety and efficiency.
5.3 Consultation with a doctor or nutritionist
Before taking collagen additives, it is recommended to consult a doctor or nutritionist, especially if you have any diseases or you take medications. A doctor or a nutritionist can help you choose the most suitable supplement and determine the optimal dosage.
Section 6: Additional ways to improve collagen assimilation
In addition to choosing the correct collagen additive, there are several additional ways to improve collagen absorption:
- Take a collagen on an empty stomach: Reception of collagen on an empty stomach can improve its assimilation, since at this time the stomach is less than other food substances that can compete for absorption.
- Combine collagen with vitamin C: Vitamin C improves collagen assimilation and stimulates its synthesis.
- Use products rich in collagen: Include products rich in collagen in your diet, such as bone broth, gelatin and poultry skin.
- Support for a healthy lifestyle: A healthy lifestyle, including a balanced nutrition, regular physical exercises and a sufficient amount of sleep, can improve collagen assimilation and support its synthesis in the body.
- Avoid factors that destroy collagen: Limit the consumption of sugar, processed foods and alcohol, which can destroy collagen and slow down its synthesis. Smoking also negatively affects the synthesis of collagen.
Section 7: Collagen dosage
The recommended dosage of collagen varies depending on the purpose of the application and individual characteristics of the body. In general, the dosages of hydrolyzed collagen are usually from 2.5 to 15 grams per day. The dosage of non-reinatured collagen type II (UC-II) is usually 40 mg per day. It is important to follow the instructions on the packaging of the product and consult a doctor or nutritionist to determine the optimal dosage for you.
Section 8: side effects and contraindications
Collagen additives are usually safe for most people. However, in some cases, side effects can occur, such as:
- Digestive disorders: Some people may experience digestive disorders, such as bloating, constipation or diarrhea, when taking collagen additives.
- Allergic reactions: People with allergies to fish, cattle, pigs or poultry may occur allergic reactions to collagen additives obtained from these sources.
- Calcium increase: Collagen supplements obtained from bones can increase the level of calcium in the blood. People with hypercalcemia should be careful when taking these additives.
Collagen additives are contraindicated to people with allergies to any of the product ingredients. Pregnant and lactating women should consult a doctor before taking collagen additives.
Section 9: Interaction with drugs
Collagen additives can interact with some drugs, such as:
- Anticoagulants: Collagen additives can enhance the effect of anticoagulants, increasing the risk of bleeding.
- Preparations for the treatment of thyroid gland: Collagen additives can reduce the effectiveness of drugs for the treatment of thyroid gland.
If you take any medicine, consult a doctor before taking collagen additives.
Section 10: Conclusion
Collagen is an important protein necessary to maintain the health and functioning of various organs and systems of the body. Collagen additives can be useful for improving skin elasticity, strengthening bones, maintaining joint health and improving the general state of health.
For optimal assimilation of collagen, it is important to choose a hydrolyzed collagen (collagen peptides) from a reliable source and combine it with vitamin C. It is also important to take into account the individual characteristics of the body and consult a doctor or nutritionist before taking collagen additives.